Gene Information gene info

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GENE：MTX2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTX2
FullNmae metaxin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7506
EnsembleID ENSG00000128654
Uniprot O75431

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTX2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MTX2 GO:0001401,GO:0001401,GO:0001401,GO:0005515,GO:0005730,GO:0005737,GO:0005739,GO:0005741,GO:0006839,GO:0007005,GO:0007007,GO:0045040,GO:0140275

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MTX2 hsa:10651 path:hsa04137 Mitophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 MTX2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 MTX2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 MTX2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 MTX2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MTX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CHCHD3 MTX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM22 MTX2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
C1QTNF2 MTX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KASH5 MTX2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SAMM50 MTX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHB MTX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1CA MTX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAQ MTX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBQLN2 MTX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VDAC2 MTX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHB2 MTX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RHOH MTX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CD244 MTX2 25348397 N/A physical interaction ComPPI
HNRNPR MTX2 25348397 N/A physical interaction ComPPI
IMMT MTX2 17624330 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2B4 MTX2 25348397 N/A physical interaction ComPPI
MTX1 MTX2 10381257 17510655 24234451 25348397 27898060 colocalization two hybrid,blue native page,in vitro ComPPI,IntAct,OmniPath
MTX2 SLC25A3 25348397 N/A physical interaction ComPPI
MTX2 MOV10 25348397 N/A physical interaction ComPPI
MTX2 APOOL 25348397 N/A physical interaction ComPPI
MTX2 NDUFA4 25348397 N/A physical interaction ComPPI
MTX2 AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MTX2 SCO1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MTX2 SFXN1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MTX2 ATP5F1A 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
COX4I1 MTX2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MTX2 EED 24234451 30021884 physical association cross-linking study IntAct

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