Gene Information gene info

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GENE：NRXN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NRXN1
FullNmae neurexin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8008
EnsembleID ENSG00000179915
Uniprot P58400|Q9ULB1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NRXN1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NRXN1 GO:0005246,GO:0005509,GO:0005515,GO:0005730,GO:0005783,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0007158,GO:0007268,GO:0007269,GO:0007411,GO:0007416,GO:0007612,GO:0009986,GO:0030534,GO:0031965,GO:0031982,GO:0033130,GO:0035176,GO:0038023,GO:0042297,GO:0042734,GO:0042995,GO:0043025,GO:0050839,GO:0050885,GO:0051965,GO:0051968,GO:0071625,GO:0090129,GO:0097104,GO:0097109,GO:0097116,GO:0097118,GO:0097119,GO:2000463

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NRXN1 hsa:9378 path:hsa04514 Cell adhesion molecules - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 NRXN1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 NRXN1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 NRXN1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 NRXN1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NRXN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TCF7L2 NRXN1 22777675 trascriptional regulation,stimulation inferred by curator TFlink
TCF7L2 NRXN1 22777675 trascriptional regulation,stimulation inferred by curator TFlink
TCF4 NRXN1 22777675 trascriptional regulation,stimulation inferred by curator TFlink
TCF4 NRXN1 22777675 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005D986D NRXN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 NRXN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000010F787 NRXN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 NRXN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E NRXN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 NRXN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 NRXN1 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000393C7 NRXN1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001B9F58 NRXN1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003AD231 NRXN1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CASK NRXN1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
NLGN3 NRXN1 25348397 N/A physical interaction ComPPI
ARHGAP26 NRXN1 25348397 N/A physical interaction ComPPI
ARHGAP26 NRXN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ELOA NRXN1 25348397 N/A physical interaction ComPPI
ELOA NRXN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARHGAP10 NRXN1 25348397 N/A physical interaction ComPPI
ARHGAP10 NRXN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MACF1 NRXN1 25348397 N/A physical interaction ComPPI
MACF1 NRXN1 25348397 N/A two hybrid,physical interaction ComPPI
NLGN1 NRXN1 25348397 N/A physical interaction ComPPI
NLGN1 NRXN1 14522992 14525934 25348397 8576240 N/A experimental interaction detection,physical interaction ComPPI,HPRD
NLGN2 NRXN1 25348397 N/A physical interaction ComPPI
NLGN2 NRXN1 14525934 25348397 8576240 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SIPA1L1 NRXN1 25348397 N/A physical interaction ComPPI
SIPA1L1 NRXN1 12421765 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PDZD2 NRXN1 25348397 N/A physical interaction ComPPI
PDZD2 NRXN1 12421765 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MYO16 NRXN1 25348397 N/A physical interaction ComPPI
AFDN NRXN1 25348397 N/A physical interaction ComPPI
AFDN NRXN1 25348397 N/A physical interaction ComPPI
NRXN1 ATP13A2 25348397 N/A physical interaction ComPPI
NRXN1 TULP1 25348397 N/A physical interaction ComPPI
SYT13 NRXN1 11171101 25348397 27898060 N/A physical interaction ComPPI,OmniPath
NRXN1 SYT1 11243866 14525934 8901523 N/A experimental interaction detection HPRD
NRXN1 CASK 11036064 14525934 8786425 N/A experimental interaction detection,two hybrid HPRD
NRXN1 SYT4 14525934 8901523 N/A experimental interaction detection HPRD
NRXN1 SYT2 14525934 8901523 N/A experimental interaction detection HPRD
NRXN1 APBA1 11036064 14525934 N/A experimental interaction detection HPRD
NRXN1 APBA2 11036064 14525934 N/A experimental interaction detection HPRD
SYT7 NRXN1 14525934 8901523 N/A experimental interaction detection HPRD
RPH3A NRXN1 14525934 8901523 N/A experimental interaction detection HPRD
SDCBP2 NRXN1 11152476 14525934 N/A two hybrid HPRD
PRKDC NRXN1 24234451 30021884 physical association cross-linking study IntAct
CASK NRXN1 11036064 18423203 27898060 8786425 N/A N/A OmniPath
NXPH1 NRXN1 27898060 8699246 9856994 stimulant N/A OmniPath

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