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GENE：NUDT16L1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUDT16L1
FullNmae nudix hydrolase 16 like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28154
EnsembleID ENSG00000168101
Uniprot Q9BRJ7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUDT16L1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NUDT16L1 GO:0003723,GO:0005515,GO:0005634,GO:0005634,GO:0030515,GO:0030515,GO:2001033

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NUDT16L1 hsa:84309 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 NUDT16L1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 NUDT16L1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NUDT16L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NUDT16L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NUDT16L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NUDT16L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NUDT16L1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CRYAB NUDT16L1 25348397 N/A physical interaction ComPPI
TP53BP1 NUDT16L1 25348397 N/A physical interaction ComPPI
BMI1 NUDT16L1 25348397 N/A physical interaction ComPPI
MCM2 NUDT16L1 25348397 N/A physical interaction ComPPI
KRT31 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PNMA1 NUDT16L1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HNRNPH2 NUDT16L1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VEGFB NUDT16L1 25348397 N/A physical interaction ComPPI
JUN NUDT16L1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SMARCD1 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COPS5 NUDT16L1 25348397 N/A physical interaction ComPPI
CUL3 NUDT16L1 25348397 N/A physical interaction ComPPI
TRAF2 NUDT16L1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NEDD4L NUDT16L1 25348397 N/A physical interaction ComPPI
NEDD8 NUDT16L1 25348397 N/A physical interaction ComPPI
CUL4B NUDT16L1 25348397 N/A physical interaction ComPPI
CUL1 NUDT16L1 25348397 N/A physical interaction ComPPI
RNF2 NUDT16L1 25348397 N/A physical interaction ComPPI
GABARAP NUDT16L1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
IKZF3 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRAF4 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CUL7 NUDT16L1 25348397 N/A physical interaction ComPPI
CAND1 NUDT16L1 25348397 N/A physical interaction ComPPI
HNRNPF NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HNRNPH1 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CABP2 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HECW2 NUDT16L1 25348397 N/A physical interaction ComPPI
ZRANB1 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INCA1 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
APP NUDT16L1 25348397 N/A physical interaction ComPPI
TP53 NUDT16L1 22653443 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LRRK1 NUDT16L1 24234451 24947832 25348397 N/A protein array ComPPI,IntAct
TRIM68 NUDT16L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT16L1 NUDT16 25348397 N/A physical interaction ComPPI

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