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GENE：PACSIN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PACSIN1
FullNmae protein kinase C and casein kinase substrate in neurons 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8570
EnsembleID ENSG00000124507
Uniprot Q9BY11

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PACSIN1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PACSIN1 GO:0005515,GO:0005543,GO:0005543,GO:0005737,GO:0005737,GO:0005768,GO:0005829,GO:0005886,GO:0005886,GO:0007010,GO:0007015,GO:0008092,GO:0030100,GO:0030137,GO:0030659,GO:0032587,GO:0042802,GO:0043679,GO:0045202,GO:0045806,GO:0048471,GO:0048488,GO:0048812,GO:0048812,GO:0072657,GO:0072659,GO:0097320,GO:0097320,GO:0098684,GO:0098833,GO:1900006,GO:1900006

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FASLG PACSIN1 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 PACSIN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 PACSIN1 19559773 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PACSIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A405B PACSIN1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 PACSIN1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000237E04 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DABC0 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000059EB31 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075ADAC PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F9738 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004929F1 PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002373FD PACSIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PAK6 PACSIN1 22135298 phosphorylation N/A PhosphoSite
PACSIN1 PACSIN2 25361965 interaction type N/A PTMCode2
PACSIN2 PACSIN1 25361965 interaction type N/A PTMCode2
PACSIN1 ARHGAP17 25361965 interaction type N/A PTMCode2
ARHGAP17 PACSIN1 25361965 interaction type N/A PTMCode2
PACSIN1 DNM2 25361965 interaction type N/A PTMCode2
DNM2 PACSIN1 25361965 interaction type N/A PTMCode2
PACSIN1 DNM1 25361965 interaction type N/A PTMCode2
DNM1 PACSIN1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PLEKHF2 PACSIN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WASL PACSIN1 12426380 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
HSPA8 PACSIN1 25348397 N/A physical interaction ComPPI
PACSIN3 PACSIN1 11082044 14525934 24234451 25348397 25416956 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
CST1 PACSIN1 25348397 N/A physical interaction ComPPI
FTH1 PACSIN1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PPP2R1A PACSIN1 25348397 N/A physical interaction ComPPI
WAS PACSIN1 25348397 N/A physical interaction ComPPI
PACSIN1 SOS1 11352907 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
PACSIN1 DNM1 11082044 14525934 15252009 24234451 25348397 9950691 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PACSIN1 SYNJ1 11082044 11292345 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PACSIN1 PACSIN2 14525934 16189514 20936779 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PACSIN1 TRPV4 14525934 16627472 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PACSIN1 KAT7 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PACSIN1 HTT 12354780 14525934 17161366 17500595 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
PACSIN1 CARS1 25348397 N/A physical interaction ComPPI
PACSIN1 CYFIP2 25348397 N/A physical interaction ComPPI
PACSIN1 ASAP1 25348397 N/A physical interaction ComPPI
PACSIN1 DNM2 25348397 N/A physical interaction ComPPI
PACSIN1 HSPA1A 25348397 N/A physical interaction ComPPI
PACSIN1 HSPA1B 25348397 N/A physical interaction ComPPI
PACSIN1 KHDRBS1 25348397 N/A physical interaction ComPPI
PACSIN1 MICALL1 25348397 N/A physical interaction ComPPI
PACSIN1 APBB1IP 25348397 N/A physical interaction ComPPI
PACSIN1 WIPF1 25348397 N/A physical interaction ComPPI
PACSIN1 MT-ATP8 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 SPTBN1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 TPM4 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 GAS7 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 COBLL1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 COBL 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 EHBP1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 JADE2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 ANKRD24 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 RTKN2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PACSIN1 SYNM 25348397 N/A physical interaction ComPPI
PACSIN1 POT1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PACSIN1 MYC 25348397 N/A physical interaction ComPPI
PACSIN1 ITCH 25348397 N/A physical interaction ComPPI
PACSIN1 MPRIP 25348397 N/A physical interaction ComPPI
PACSIN1 RAI14 25348397 N/A physical interaction ComPPI
PACSIN1 TRIOBP 25348397 N/A physical interaction ComPPI
PACSIN1 FASLG 16318909 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
PACSIN1 NELFB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ARHGAP17 PACSIN1 11431473 14525934 20936779 24234451 25348397 physical association experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro ComPPI,HPRD,IntAct
PACSIN1 WASF2 14525934 9950691 N/A experimental interaction detection HPRD
PACSIN1 PACSIN1 11082044 14525934 N/A experimental interaction detection,two hybrid HPRD
FASLG PACSIN1 16318909 24291222 27898060 N/A N/A OmniPath
PAK6 PACSIN1 24204982 27898060 N/A N/A OmniPath

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