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GENE：PACSIN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PACSIN2
FullNmae protein kinase C and casein kinase substrate in neurons 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8571
EnsembleID ENSG00000100266
Uniprot Q9UNF0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PACSIN2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PACSIN2 GO:0005515,GO:0005543,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005901,GO:0005911,GO:0005925,GO:0007010,GO:0008092,GO:0016607,GO:0030036,GO:0030100,GO:0032587,GO:0034451,GO:0036010,GO:0042802,GO:0043231,GO:0045296,GO:0045806,GO:0048858,GO:0050804,GO:0055038,GO:0070062,GO:0070300,GO:0070836,GO:0072584,GO:0097320,GO:0097320,GO:0097320,GO:0098978

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FASLG PACSIN2 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PACSIN2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 PACSIN2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 PACSIN2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PACSIN2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 PACSIN2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PACSIN2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PACSIN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PACSIN2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000AA464 PACSIN2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000358C16 PACSIN2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 PACSIN2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 PACSIN2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002EF20A PACSIN2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 PACSIN2 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PACSIN1 PACSIN2 25361965 interaction type N/A PTMCode2
PACSIN2 PACSIN1 25361965 interaction type N/A PTMCode2
PACSIN2 ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 PACSIN2 25361965 interaction type N/A PTMCode2
PACSIN2 DNM2 25361965 interaction type N/A PTMCode2
DNM2 PACSIN2 25361965 interaction type N/A PTMCode2
PACSIN2 FASLG 25361965 interaction type N/A PTMCode2
FASLG PACSIN2 25361965 interaction type N/A PTMCode2
PACSIN2 DNM1 25361965 interaction type N/A PTMCode2
DNM1 PACSIN2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
VASN PACSIN2 25348397 N/A physical interaction ComPPI
WASL PACSIN2 12426380 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
FTL PACSIN2 25348397 N/A physical interaction ComPPI
HSPA8 PACSIN2 25348397 N/A physical interaction ComPPI
PACSIN3 PACSIN2 11082044 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
CST1 PACSIN2 25348397 N/A physical interaction ComPPI
PBX4 PACSIN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FTH1 PACSIN2 25348397 N/A physical interaction ComPPI
PPP2R1A PACSIN2 25348397 N/A physical interaction ComPPI
WAS PACSIN2 25348397 N/A physical interaction ComPPI
MEOX2 PACSIN2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PACSIN1 PACSIN2 14525934 16189514 20936779 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
SWAP70 PACSIN2 25348397 N/A physical interaction ComPPI
TRPV4 PACSIN2 14525934 16627472 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
KHDRBS1 PACSIN2 25348397 N/A physical interaction ComPPI
CDH1 PACSIN2 25348397 N/A physical interaction ComPPI
DNM1 PACSIN2 25348397 N/A physical interaction ComPPI
APBB1IP PACSIN2 25348397 N/A physical interaction ComPPI
WIPF2 PACSIN2 25348397 N/A physical interaction ComPPI
HSPA1A PACSIN2 25348397 N/A physical interaction ComPPI
HSPA1B PACSIN2 25348397 N/A physical interaction ComPPI
PTGES3 PACSIN2 25348397 N/A physical interaction ComPPI
MYC PACSIN2 25348397 N/A physical interaction ComPPI
ST13 PACSIN2 25348397 N/A physical interaction ComPPI
PTPN12 PACSIN2 25348397 N/A physical interaction ComPPI
PPP2R5C PACSIN2 25348397 N/A physical interaction ComPPI
EWSR1 PACSIN2 25348397 N/A physical interaction ComPPI
MICALL1 PACSIN2 25348397 N/A physical interaction ComPPI
SPTBN1 PACSIN2 25348397 N/A physical interaction ComPPI
FASLG PACSIN2 12023017 14525934 16318909 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
HTT PACSIN2 25348397 N/A physical interaction ComPPI
GTF2E2 PACSIN2 25348397 N/A physical interaction ComPPI
ANKS1A PACSIN2 25348397 N/A physical interaction ComPPI
ASAP1 PACSIN2 16636290 24234451 25348397 N/A physical interaction,enzyme linked immunosorbent assay ComPPI,IntAct
RAI14 PACSIN2 25348397 N/A physical interaction ComPPI
ITCH PACSIN2 25348397 N/A physical interaction ComPPI
SYNJ1 PACSIN2 25348397 N/A physical interaction ComPPI
KAT7 PACSIN2 25348397 N/A physical interaction ComPPI
WIPF1 PACSIN2 25348397 N/A physical interaction ComPPI
CYFIP2 PACSIN2 25348397 N/A physical interaction ComPPI
TRIM25 PACSIN2 25348397 N/A physical interaction ComPPI
TERF1 PACSIN2 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
POT1 PACSIN2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
SYNM PACSIN2 25348397 N/A physical interaction ComPPI
GSC2 PACSIN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MPRIP PACSIN2 25348397 N/A physical interaction ComPPI
TERF2IP PACSIN2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TGOLN2 PACSIN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
UGP2 PACSIN2 25348397 N/A physical interaction ComPPI
TPM4 PACSIN2 25348397 N/A physical interaction ComPPI
ARHGAP17 PACSIN2 25348397 N/A physical interaction ComPPI
PACSIN2 CARS1 25348397 N/A physical interaction ComPPI
PACSIN2 DNM2 16551695 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
PACSIN2 SBK1 25348397 N/A physical interaction ComPPI
PACSIN2 MT-ATP8 25348397 N/A physical interaction ComPPI
PACSIN2 GAS7 25348397 N/A physical interaction ComPPI
PACSIN2 COBLL1 25348397 N/A physical interaction ComPPI
PACSIN2 COBL 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PACSIN2 EHBP1 25348397 N/A physical interaction ComPPI
PACSIN2 JADE2 25348397 N/A physical interaction ComPPI
PACSIN2 ANKRD24 25348397 N/A physical interaction ComPPI
PACSIN2 RTKN2 25348397 N/A physical interaction ComPPI
PACSIN2 CERT1 25348397 N/A physical interaction ComPPI
PACSIN2 PLOD2 25348397 N/A physical interaction ComPPI
PACSIN2 MOV10 25348397 N/A physical interaction ComPPI
PACSIN2 NXF1 25348397 N/A physical interaction ComPPI
PACSIN2 HSPD1 25348397 N/A physical interaction ComPPI
PACSIN2 ST13P4 25348397 N/A physical interaction ComPPI
PACSIN2 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PACSIN2 ERP44 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN2 TRIOBP 25348397 N/A physical interaction ComPPI
PACSIN2 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
PACSIN2 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PACSIN2 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SHBG PACSIN2 25348397 N/A physical interaction ComPPI
THG1L PACSIN2 25348397 N/A physical interaction ComPPI
PACSIN2 PACSIN2 14525934 16189514 20188097 24234451 25416956 physical association x-ray crystallography,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach,two hybrid HPRD,IntAct
FASLG PACSIN2 12023017 16318909 24291222 27898060 N/A N/A OmniPath
PACSIN2 FASLG 12023017 16318909 24291222 27898060 N/A N/A OmniPath

Visualization










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