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GENE：PACSIN3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PACSIN3
FullNmae protein kinase C and casein kinase substrate in neurons 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8572
EnsembleID ENSG00000165912
Uniprot Q9UKS6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PACSIN3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PACSIN3 GO:0005515,GO:0005543,GO:0005737,GO:0005737,GO:0005768,GO:0005829,GO:0005886,GO:0005886,GO:0006897,GO:0007010,GO:0008092,GO:0008289,GO:0019855,GO:0030100,GO:0042802,GO:0045806,GO:0051044,GO:0051926,GO:0070062,GO:0097320,GO:0097320

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FASLG PACSIN3 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 PACSIN3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PACSIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PACSIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PACSIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PACSIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PACSIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PACSIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PACSIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PACSIN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PACSIN3 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
PACSIN3 ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 PACSIN3 25361965 interaction type N/A PTMCode2
PACSIN3 DNM2 25361965 interaction type N/A PTMCode2
DNM2 PACSIN3 25361965 interaction type N/A PTMCode2
PACSIN3 DNM1 25361965 interaction type N/A PTMCode2
DNM1 PACSIN3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
WASL PACSIN3 11082044 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct
HSPA8 PACSIN3 25348397 N/A physical interaction ComPPI
SPRY2 PACSIN3 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PACSIN3 PACSIN1 11082044 14525934 24234451 25348397 25416956 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PACSIN3 LGALS13 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PACSIN3 SOS1 14525934 14679214 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
PACSIN3 SOS2 14525934 14679214 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
PACSIN3 DNM1 11082044 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PACSIN3 PACSIN2 11082044 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
PACSIN3 ADAM15 10531379 14525934 16374509 24234451 25348397 physical association two hybrid,experimental interaction detection,filter binding,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PACSIN3 SYNJ1 11082044 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PACSIN3 ASAP1 14525934 15719014 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PACSIN3 ASAP2 14525934 15719014 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PACSIN3 ADAM12 12952982 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PACSIN3 TRPV4 14525934 16627472 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PACSIN3 PAK2 14525934 16374509 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PACSIN3 PYGM 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 RPL23A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 NOL3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 CARS1 25348397 N/A physical interaction ComPPI
PACSIN3 CYFIP2 25348397 N/A physical interaction ComPPI
PACSIN3 DNM2 25348397 N/A physical interaction ComPPI
PACSIN3 HSPA1A 25348397 N/A physical interaction ComPPI
PACSIN3 HSPA1B 25348397 N/A physical interaction ComPPI
PACSIN3 KHDRBS1 25348397 N/A physical interaction ComPPI
PACSIN3 MICALL1 25348397 N/A physical interaction ComPPI
PACSIN3 APBB1IP 25348397 N/A physical interaction ComPPI
PACSIN3 WIPF1 25348397 N/A physical interaction ComPPI
PACSIN3 SBK1 25348397 N/A physical interaction ComPPI
PACSIN3 ITSN1 25348397 N/A physical interaction ComPPI
PACSIN3 TERF2IP 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PACSIN3 FKBP3 25348397 N/A physical interaction ComPPI
PACSIN3 PAN2 25348397 N/A physical interaction ComPPI
PACSIN3 GCH1 25348397 N/A physical interaction ComPPI
PACSIN3 RAF1 25348397 N/A physical interaction ComPPI
PACSIN3 CCDC8 25348397 N/A physical interaction ComPPI
PACSIN3 COBL 25348397 N/A physical interaction ComPPI
PACSIN3 COBLL1 25348397 N/A physical interaction ComPPI
PACSIN3 ACTR1A 25348397 N/A physical interaction ComPPI
PACSIN3 ACTR1B 25348397 N/A physical interaction ComPPI
PACSIN3 DCTN1 25348397 N/A physical interaction ComPPI
PACSIN3 FNBP1L 25348397 N/A physical interaction ComPPI
PACSIN3 HSPA5 25348397 N/A physical interaction ComPPI
PACSIN3 HSPD1 25348397 N/A physical interaction ComPPI
PACSIN3 PCNA 25348397 N/A physical interaction ComPPI
PACSIN3 ST13 25348397 N/A physical interaction ComPPI
PACSIN3 ST13P4 25348397 N/A physical interaction ComPPI
PACSIN3 CLNK 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PACSIN3 XPO1 25348397 N/A physical interaction ComPPI
PACSIN3 CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 GJB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 MYH9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 PDGFRA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 POLH 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 RPL10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 IQGAP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 ATP6AP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 SYNPO 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 ANLN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PACSIN3 RAI14 25348397 N/A physical interaction ComPPI
PACSIN3 ADAM9 10531379 24234451 25348397 physical association two hybrid,pull down ComPPI,IntAct
PACSIN3 FBL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PACSIN3 GOT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PACSIN3 MAPK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PACSIN3 PEBP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PACSIN3 FASLG 16318909 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
PACSIN3 SMARCD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PACSIN3 KRTAP12-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PACSIN3 DDIT4L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WAS PACSIN3 25348397 N/A physical interaction ComPPI
PACSIN3 PACSIN3 24234451 physical association two hybrid array,two hybrid prey pooling approach IntAct
NCBP3 PACSIN3 24234451 26382858 association pull down IntAct
PDIA3 PACSIN3 24234451 30021884 physical association cross-linking study IntAct
PACSIN3 TRPV4 16627472 18174177 27898060 stimulant N/A OmniPath
FASLG PACSIN3 16318909 24291222 27898060 N/A N/A OmniPath

Visualization










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