GENE：PEX3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PEX3 |
| FullNmae | peroxisomal biogenesis factor 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:8858 |
| EnsembleID | ENSG00000034693 |
| Uniprot | P56589 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PEX3 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PEX3 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PEX3 | GO:0005515,GO:0005654,GO:0005777,GO:0005777,GO:0005778,GO:0005778,GO:0005778,GO:0005783,GO:0007031,GO:0008289,GO:0016020,GO:0030674,GO:0032991,GO:0032994,GO:0045046,GO:0045046 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PEX3 | hsa:8504 | path:hsa04146 | Peroxisome - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PEX3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | PEX3 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | PEX3 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | PEX3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | PEX3 | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| MYC | PEX3 | 12695333 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | PEX3 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | PEX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PEX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PEX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | PEX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PEX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| JUN | PEX3 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TFAP2A | PEX3 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| DHX15 | PEX3 | 25348397 | N/A | physical interaction | ComPPI |
| PEX3 | PEX19 | 10430017 10704444 11390669 11883941 12096124 14525934 16189514 16280322 19017643 19451657 19948495 21102411 22643220 24234451 25007327 25348397 25416956 26186194 27107012 27898060 29997244 9418908 | physical association | anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid,experimental interaction detection,far western blotting,pull down,surface plasmon resonance,ubiquitin reconstruction,x-ray crystallography,physical interaction,two hybrid array,two hybrid pooling approach,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| PEX3 | ABCD3 | 25348397 | N/A | physical interaction | ComPPI |
| PEX3 | ABCD1 | 25348397 | N/A | physical interaction | ComPPI |
| PEX3 | CHCHD4 | 25348397 | N/A | physical interaction | ComPPI |
| PEX3 | HNRNPR | 25348397 | N/A | physical interaction | ComPPI |
| PEX3 | PEX14 | 21525035 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
| PEX3 | PEX16 | 16280322 24234451 25348397 | N/A | anti tag coimmunoprecipitation | ComPPI,IntAct |
| PEX3 | PEX26 | 16280322 24234451 25348397 | N/A | anti tag coimmunoprecipitation | ComPPI,IntAct |
| PEX3 | HSCB | 24234451 25348397 28380382 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| HNRNPF | PEX3 | 25348397 | N/A | physical interaction | ComPPI |
| PCBP1 | PEX3 | 24234451 30021884 | physical association | cross-linking study | IntAct |