Gene Information gene info

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GENE：PHYKPL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PHYKPL
FullNmae 5-phosphohydroxy-L-lysine phospho-lyase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28249
EnsembleID ENSG00000175309
Uniprot Q8IUZ5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PHYKPL immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PHYKPL GO:0005515,GO:0005759,GO:0008483,GO:0016829,GO:0030170,GO:0042802

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PHYKPL hsa:85007 path:hsa00310 Lysine degradation - Homo sapiens (human)
PHYKPL hsa:85007 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 PHYKPL 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PHYKPL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PHYKPL 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PHYKPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PHYKPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PHYKPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PHYKPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000075ADAC PHYKPL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 PHYKPL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F9738 PHYKPL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 PHYKPL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000048B5E9 PHYKPL 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
USO1 PHYKPL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HNRNPL PHYKPL 25348397 N/A physical interaction ComPPI
POT1 PHYKPL 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
LNX2 PHYKPL 25348397 N/A physical interaction ComPPI
PHYKPL ZNF684 25348397 N/A physical interaction ComPPI

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