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GENE：PIN4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PIN4
FullNmae peptidylprolyl cis/trans isomerase, NIMA-interacting 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8992
EnsembleID ENSG00000102309
Uniprot Q9Y237

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PIN4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PIN4 GO:0003677,GO:0003723,GO:0003755,GO:0005515,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005759,GO:0005819,GO:0006364

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PIN4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PIN4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 PIN4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 PIN4 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 PIN4 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
AIMP2 PIN4 25348397 N/A physical interaction ComPPI
ZBTB9 PIN4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAD21 PIN4 25348397 N/A physical interaction ComPPI
FATE1 PIN4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PNMA1 PIN4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EZH2 PIN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CHST15 PIN4 25348397 N/A physical interaction ComPPI
DNM1 PIN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RRBP1 PIN4 25348397 N/A physical interaction ComPPI
CSNK2A1 PIN4 12860119 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SPTAN1 PIN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSNK2A2 PIN4 12860119 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EGFR PIN4 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
CCT5 PIN4 25348397 N/A physical interaction ComPPI
TIMM44 PIN4 25348397 N/A physical interaction ComPPI
DYNC1H1 PIN4 25348397 N/A physical interaction ComPPI
MARS1 PIN4 25348397 N/A physical interaction ComPPI
ASCC2 PIN4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PIN4 FBL 11960984 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
PIN4 NDUFA7 25348397 N/A physical interaction ComPPI
PIN4 DNAJC8 25348397 N/A physical interaction ComPPI
PIN4 SLIRP 25348397 N/A physical interaction ComPPI
PIN4 RPS19 25348397 N/A physical interaction ComPPI
PIN4 DDX42 25348397 N/A physical interaction ComPPI
PIN4 SRPRB 25348397 N/A physical interaction ComPPI
PIN4 NDUFA2 25348397 N/A physical interaction ComPPI
PIN4 SCO2 25348397 N/A physical interaction ComPPI
PIN4 VDAC3 25348397 N/A physical interaction ComPPI
PIN4 UBE2S 25348397 N/A physical interaction ComPPI
PIN4 MAGEA11 25348397 N/A physical interaction ComPPI
PIN4 CEP72 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PIN4 FAM9B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PIN4 SHMT2 25348397 N/A physical interaction ComPPI
PIN4 EEF1AKNMT 25348397 N/A physical interaction ComPPI
PIN4 RTF2 25348397 N/A physical interaction ComPPI
PIN4 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PIN4 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PIN4 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
ERH PIN4 23236152 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHEK2 PIN4 15024067 27898060 N/A N/A OmniPath
CSNK2A1 PIN4 12860119 27898060 N/A N/A OmniPath
ZAP70 PIN4 12860119 27898060 N/A N/A OmniPath
CSNK2A2 PIN4 12860119 27898060 N/A N/A OmniPath

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