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GENE：PLD3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLD3
FullNmae phospholipase D family member 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17158
EnsembleID ENSG00000105223
Uniprot Q8IV08

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLD3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLD3 GO:0000139,GO:0002376,GO:0004630,GO:0005515,GO:0005765,GO:0005789,GO:0006259,GO:0006954,GO:0014902,GO:0031901,GO:0031902,GO:0043202,GO:0045145,GO:0070062,GO:1900015

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLD3 hsa:23646 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
PLD3 hsa:23646 path:hsa00565 Ether lipid metabolism - Homo sapiens (human)
PLD3 hsa:23646 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PLD3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PLD3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PLD3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PLD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PLD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PLD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PLD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PLD3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D PLD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE PLD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD PLD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000031E12 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A07C1 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000B1C9 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000009A9A2 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000059EB31 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000019907A PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000137EDE PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000B989F PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00006097A6 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000037E170 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003758F0 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F9738 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000011A030 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000017EA6A PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A608 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 PLD3 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TK1 PLD3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BCL2L1 PLD3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPP1 PLD3 25348397 N/A physical interaction ComPPI
HGS PLD3 25348397 N/A physical interaction ComPPI
NTRK1 PLD3 25348397 N/A physical interaction ComPPI
CANX PLD3 24234451 25348397 29568061 association pull down ComPPI,IntAct
HNRNPL PLD3 25348397 N/A physical interaction ComPPI
CFTR PLD3 25348397 N/A physical interaction ComPPI
EVC2 PLD3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EGFR PLD3 25348397 N/A physical interaction ComPPI
FUBP1 PLD3 25348397 N/A physical interaction ComPPI
STK11 PLD3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EIF2S3 PLD3 25348397 N/A physical interaction ComPPI
CUL7 PLD3 25348397 N/A physical interaction ComPPI
NFKB1 PLD3 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
PPP5C PLD3 25348397 N/A physical interaction ComPPI
HNRNPH3 PLD3 25348397 N/A physical interaction ComPPI
FBXO6 PLD3 25348397 N/A physical interaction ComPPI
ANXA7 PLD3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLD3 LTN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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