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GENE：POLR1E

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POLR1E
FullNmae RNA polymerase I subunit E
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17631
EnsembleID ENSG00000137054
Uniprot Q9GZS1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POLR1E immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
POLR1E GO:0001179,GO:0001188,GO:0001650,GO:0003677,GO:0005515,GO:0005654,GO:0005654,GO:0005730,GO:0005736,GO:0006362,GO:0042790

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
POLR1E hsa:64425 path:hsa03020 RNA polymerase - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 POLR1E 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 POLR1E 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 POLR1E 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000355E82 POLR1E 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A POLR1E 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 POLR1E 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 POLR1E 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 POLR1E 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C POLR1E 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00007455B8 POLR1E 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000812128 POLR1E 24297251 direct interaction,inhibition high throughput sequencing StarBase

Source Target Pmid Interactiontype Methods Database
UBTF POLR1E 25361965 interaction type N/A PTMCode2
POLR1E UBTF 25361965 interaction type N/A PTMCode2
NME1 POLR1E 25361965 interaction type N/A PTMCode2
POLR1E NME1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DDX6 POLR1E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3H POLR1E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LZTS2 POLR1E 25348397 N/A physical interaction ComPPI
MRM3 POLR1E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KBTBD7 POLR1E 25348397 N/A physical interaction ComPPI
DDX20 POLR1E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SKAP1 POLR1E 25348397 N/A physical interaction ComPPI
PAXIP1 POLR1E 25348397 N/A physical interaction ComPPI
UBTF POLR1E 11592397 11698641 14525934 15226435 16582105 25348397 27898060 8641287 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
POLR1G POLR1E 14525934 15226435 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
POLR1E TAF1C 25348397 N/A in vitro ComPPI
POLR1E POLR1B 14525934 15226435 25348397 9254723 N/A experimental interaction detection,in vitro ComPPI,HPRD
POLR1E NFKBIB 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
POLR1E HNRNPUL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1E QPCTL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1E POLR1C 14525934 17353931 24234451 25348397 9254723 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
POLR1E SUPT16H 19214185 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1E RRN3 19214185 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1E SMARCAD1 25348397 N/A physical interaction ComPPI
POLR1E CEBPA 25348397 N/A physical interaction ComPPI
POLR1E ARRB1 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1E CPSF3 25348397 N/A physical interaction ComPPI
POLR1E RNF2 25348397 N/A physical interaction ComPPI
POLR1E GPN3 25348397 N/A physical interaction ComPPI
POLR1E DDX18 25348397 N/A physical interaction ComPPI
POLR1E GRWD1 25348397 N/A physical interaction ComPPI
POLR1E NOP58 25348397 N/A physical interaction ComPPI
POLR1E POLR2F 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
POLR1E IKBKG 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
POLR1E WIZ 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
POLR1E POLR2E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1E RUNDC3A 25348397 N/A physical interaction ComPPI
POLR1E TENT5A 25348397 N/A physical interaction ComPPI
POLR1E ZNF692 25348397 N/A physical interaction ComPPI
POLR1E FOXA1 25348397 N/A physical interaction ComPPI
POLR1E MYO1C 16514417 24234451 25348397 colocalization electron microscopy,fluorescence microscopy ComPPI,IntAct
POLR1E SUN2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1E HNRNPA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1E IGF2BP3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1E HNRNPAB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1E HDX 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1E CDC37 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1E RADIL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1E RB1CC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLR1E ESR2 21182203 24234451 25348397 association cosedimentation through density gradient ComPPI,IntAct
POLR1E FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLR1A POLR1E 14525934 15226435 19214185 24234451 25348397 association experimental interaction detection,chromatography technology,physical interaction,in vitro ComPPI,HPRD,IntAct
IKZF5 POLR1E 25348397 N/A physical interaction ComPPI
TAF1D POLR1E 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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