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GENE：PPP2R5D

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPP2R5D
FullNmae protein phosphatase 2 regulatory subunit B'delta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9312
EnsembleID ENSG00000112640
Uniprot Q14738

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPP2R5D mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPP2R5D immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPP2R5D GO:0000159,GO:0004721,GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0005829,GO:0006470,GO:0006470,GO:0007165,GO:0007399,GO:0010801,GO:0019888,GO:0035307,GO:0072542

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPP2R5D hsa:5528 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa04110 Cell cycle - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa04114 Oocyte meiosis - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa04728 Dopaminergic synapse - Homo sapiens (human)
PPP2R5D hsa:5528 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NEK1 PPP2R5D 14690447 23180781 physical association two hybrid InnateDB
PPFIA1 PPP2R5D 16189514 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
PPP2R5D CHEK2 20005715 interaction type N/A PSP
PPP2R5D PPP2CA 18782753 19156129 20005715 21071413 interaction type N/A PSP,SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 PPP2R5D 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PPP2R5D 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PPP2R5D 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA PPP2R5D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPP2R5D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PPP2R5D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PPP2R5D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPP2R5D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPP2R5D 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 PPP2R5D 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003ABC4 PPP2R5D 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 PPP2R5D 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 PPP2R5D 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA PPP2R5D 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA PPP2R5D 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000009A9A2 PPP2R5D 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 PPP2R5D 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00006097A6 PPP2R5D 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075AB14 PPP2R5D 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A608 PPP2R5D 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHEK1 PPP2R5D 22135298 phosphorylation N/A PhosphoSite
PRKACA PPP2R5D 22135298 phosphorylation N/A PhosphoSite
PPP2CA PPP2R5D 25361965 interaction type N/A PTMCode2
PPP2R5D PPP2CA 25361965 interaction type N/A PTMCode2
PPP2R1A PPP2R5D 25361965 interaction type N/A PTMCode2
PPP2R5D PPP2R1A 25361965 interaction type N/A PTMCode2
PPP2R1B PPP2R5D 25361965 interaction type N/A PTMCode2
PPP2R5D PPP2R1B 25361965 interaction type N/A PTMCode2
PPM1A PPP2R5D 25361965 interaction type N/A PTMCode2
PPP2R5D PPM1A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP2R5D HAND1 14525934 14636580 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PPP2R5D HAND2 14525934 14636580 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PPP2R5D PPFIA1 14525934 16189514 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
PPP2R5D CHEK2 14525934 15380617 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PPP2R5D PPP2R1B 14525934 16541025 17540176 23555304 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PPP2R5D PPP4C 14525934 18715871 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PPP2R5D ARL2 25348397 N/A physical interaction ComPPI
PPP2R5D PPP2CA 18782753 19156129 24234451 25348397 26496610 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
PPP2R5D PPP2R1A 18782753 19293187 23555304 24234451 25348397 26496610 27173435 28330616 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach,proximity-dependent biotin identification,inference by socio-affinity scoring ComPPI,IntAct
PPP2R5D PPP2CB 18782753 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PPP2R5D GSK3B 25348397 N/A physical interaction ComPPI
PPP2R5D SOX2 25348397 N/A physical interaction ComPPI
PPP2R5D YWHAB 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2R5D ARPC2 25348397 N/A physical interaction ComPPI
PPP2R5D NIF3L1 25348397 N/A physical interaction ComPPI
PPP2R5D ARPC1B 25348397 N/A physical interaction ComPPI
PPP2R5D DHPS 25348397 N/A physical interaction ComPPI
PPP2R5D FEN1 25348397 N/A physical interaction ComPPI
PPP2R5D GOPC 25348397 N/A physical interaction ComPPI
PPP2R5D HECTD1 25348397 N/A physical interaction ComPPI
PPP2R5D LPP 25348397 N/A physical interaction ComPPI
PPP2R5D PRDX1 25348397 N/A physical interaction ComPPI
PPP2R5D PRDX2 25348397 N/A physical interaction ComPPI
PPP2R5D RANGAP1 25348397 N/A physical interaction ComPPI
PPP2R5D RPA2 25348397 N/A physical interaction ComPPI
PPP2R5D SH3GLB1 25348397 N/A physical interaction ComPPI
PPP2R5D TPD52L2 25348397 N/A physical interaction ComPPI
PPP2R5D USHBP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP2R5D FSD2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP2R5D CLOCK 25348397 N/A physical interaction ComPPI
PPP2R5D CSNK2B 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP2R5D DELEC1 25348397 N/A physical interaction ComPPI
PPP2R5D RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP2R5D CRY2 25348397 N/A physical interaction ComPPI
PPP2R5D CRY1 25348397 N/A physical interaction ComPPI
PPP2R5D CSNK1E 25348397 N/A physical interaction ComPPI
PPP2R5D BCAT1 25348397 N/A physical interaction ComPPI
PPP2R5D DNASE2B 25348397 N/A physical interaction ComPPI
PPP2R5D PPME1 25348397 N/A physical interaction ComPPI
PPP2R5D FAM43A 25348397 N/A physical interaction ComPPI
PPP2R5D WNT3A 25348397 N/A physical interaction ComPPI
PPP2R5D PON2 25348397 N/A physical interaction ComPPI
PPP2R5D CCNG1 25348397 N/A physical interaction ComPPI
PPP2R5D DNAAF5 25348397 N/A physical interaction ComPPI
PPP2R5D LARS1 25348397 N/A physical interaction ComPPI
PPP2R5D PFDN5 25348397 N/A physical interaction ComPPI
PPP2R5D PPP2R2A 25348397 N/A physical interaction ComPPI
PPP2R5D PPP2R2D 25348397 N/A physical interaction ComPPI
PPP2R5D PPP2R5A 16541025 24234451 25348397 physical association two hybrid,physical interaction,protein three hybrid ComPPI,IntAct
PPP2R5D TTC27 25348397 N/A physical interaction ComPPI
PPP2R5D PTPRF 25348397 N/A physical interaction ComPPI
PPP2R5D RRM2 25348397 N/A physical interaction ComPPI
PPP2R5D XPO6 25348397 N/A physical interaction ComPPI
PPP2R5D NTRK1 25348397 N/A physical interaction ComPPI
PPP2R5D CTR9 25348397 N/A physical interaction ComPPI
PPP2R5D CCHCR1 25348397 N/A physical interaction ComPPI
PPP2R5D CCDC61 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2R5D DUSP19 25348397 N/A physical interaction ComPPI
PPP2R5D PRR14 25348397 N/A physical interaction ComPPI
PPP2R5D CCNG2 25348397 N/A physical interaction ComPPI
PPP2R5D CELA3A 25348397 N/A physical interaction ComPPI
PPP2R5D RAPGEF5 25348397 N/A physical interaction ComPPI
PPP2R5D USP47 25348397 N/A physical interaction ComPPI
PPP2R5D FBXL3 25348397 N/A physical interaction ComPPI
PPP2R5D YBEY 25348397 N/A physical interaction ComPPI
PPP2R5D BTBD6 25348397 N/A physical interaction ComPPI
PPP2R5D RPS27 25348397 N/A physical interaction ComPPI
PPP2R5D GPR37 25348397 N/A physical interaction ComPPI
PPP2R5D GATD1 25348397 N/A physical interaction ComPPI
PPP2R5D BMP7 25348397 N/A physical interaction ComPPI
PPP2R5D PPP1CA 25348397 N/A physical interaction ComPPI
PPP2R5D CDC25C 17110335 18056802 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2R5D NEK1 14690447 24234451 25348397 physical association two hybrid ComPPI,IntAct
PPP2R5D SGO1 14525934 16541024 16541025 21666598 24234451 25348397 physical association two hybrid,experimental interaction detection,two hybrid ComPPI,HPRD,IntAct
PPP2R5D SGO2 16541025 21666598 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct
PPP2R5D MAP3K3 16407301 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PPP2R5D MAD2L1 21666598 24234451 25348397 association pull down ComPPI,IntAct
PPP2R5D DZIP1 21878643 24234451 25348397 physical association two hybrid ComPPI,IntAct
PPP2R5D BHLHE40 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
PPP2R5D DYDC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TANK PPP2R5D 24234451 30561431 association virotrap IntAct
PRKACA PPP2R5D 17301223 27898060 9688562 stimulant N/A OmniPath
ATM PPP2R5D 21460856 27898060 stimulant N/A OmniPath
PPP2R5D RAF1 16239230 27898060 stimulant N/A OmniPath

Visualization










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