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GENE：PPP6R3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPP6R3
FullNmae protein phosphatase 6 regulatory subunit 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1173
EnsembleID ENSG00000110075
Uniprot Q5H9R7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPP6R3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPP6R3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPP6R3 GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0005829,GO:0005829,GO:0005886,GO:0019888,GO:0019903,GO:0043666,GO:0043666

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PPP6R3 PPP6C 16769727 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PPP6R3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PPP6R3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PPP6R3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PPP6R3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 PPP6R3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PPP6R3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB PPP6R3 20371350 21572407 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000EED18 PPP6R3 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 PPP6R3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F PPP6R3 21572407 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000031BC7D PPP6R3 23807165 25416803 mrna cleavage,inhibition array technology TarBase
URS00002075FA PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000243FF1 PPP6R3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075A9CF PPP6R3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 PPP6R3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B PPP6R3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF PPP6R3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 PPP6R3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000D6C3F PPP6R3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 PPP6R3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6EFA PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D PPP6R3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 PPP6R3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041CB9C PPP6R3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000040EE1D PPP6R3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000160683 PPP6R3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000F0F49 PPP6R3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000007D64A PPP6R3 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TFAP4 PPP6R3 25348397 N/A physical interaction ComPPI
UTP25 PPP6R3 25348397 N/A physical interaction ComPPI
HSPA8 PPP6R3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CEP19 PPP6R3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TNFAIP3 PPP6R3 25348397 N/A physical interaction ComPPI
SNAI2 PPP6R3 25348397 N/A physical interaction ComPPI
YWHAG PPP6R3 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HSP90AB1 PPP6R3 25348397 N/A physical interaction ComPPI
NOTCH1 PPP6R3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PRKDC PPP6R3 25348397 N/A physical interaction ComPPI
GRB2 PPP6R3 12577067 24234451 25348397 association pull down ComPPI,IntAct
USP7 PPP6R3 25348397 N/A physical interaction ComPPI
GSK3B PPP6R3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSP90AA1 PPP6R3 25348397 N/A physical interaction ComPPI
NTRK1 PPP6R3 25348397 N/A physical interaction ComPPI
CSNK1E PPP6R3 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ENAH PPP6R3 25348397 N/A physical interaction ComPPI
CFTR PPP6R3 25348397 N/A physical interaction ComPPI
AP2A2 PPP6R3 25348397 N/A physical interaction ComPPI
KDM6A PPP6R3 25348397 N/A physical interaction ComPPI
ECT2 PPP6R3 25348397 N/A physical interaction ComPPI
GRK5 PPP6R3 25348397 N/A physical interaction ComPPI
XPO1 PPP6R3 25348397 N/A physical interaction ComPPI
AP2A1 PPP6R3 25348397 N/A physical interaction ComPPI
AP1B1 PPP6R3 25348397 N/A physical interaction ComPPI
HDAC2 PPP6R3 25348397 N/A physical interaction ComPPI
RNF2 PPP6R3 25348397 N/A physical interaction ComPPI
AURKA PPP6R3 25348397 N/A physical interaction ComPPI
HIF1AN PPP6R3 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PPP6C PPP6R3 18186651 21187329 24234451 24255178 25348397 28330616 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
HDAC11 PPP6R3 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC37 PPP6R3 25348397 N/A physical interaction ComPPI
TRIM25 PPP6R3 25348397 N/A physical interaction ComPPI
ELAVL1 PPP6R3 25348397 N/A physical interaction ComPPI
TINF2 PPP6R3 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
RPS6KB2 PPP6R3 25348397 N/A physical interaction ComPPI
LATS1 PPP6R3 25348397 N/A physical interaction ComPPI
BRCA1 PPP6R3 25348397 N/A physical interaction ComPPI
TERF2IP PPP6R3 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
USP49 PPP6R3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TES PPP6R3 25348397 N/A physical interaction ComPPI
EIF4A3 PPP6R3 25348397 N/A physical interaction ComPPI
USP10 PPP6R3 25348397 N/A physical interaction ComPPI
RUVBL2 PPP6R3 25348397 N/A physical interaction ComPPI
MOB1A PPP6R3 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GPHA2 PPP6R3 25348397 N/A physical interaction ComPPI
USP21 PPP6R3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NFKBIE PPP6R3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PPP6R2 PPP6R3 25348397 N/A physical interaction ComPPI
SRRT PPP6R3 25348397 N/A physical interaction ComPPI
GPSM1 PPP6R3 25348397 N/A physical interaction ComPPI
ECH1 PPP6R3 25348397 N/A physical interaction ComPPI
CEP44 PPP6R3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPP6R3 USP36 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP6R3 HDAC1 25348397 N/A physical interaction ComPPI
PPP6R3 SIRT7 25348397 N/A physical interaction ComPPI
PPP6R3 PFAS 25348397 N/A physical interaction ComPPI
PPP6R3 ANKRD28 18186651 24234451 24255178 25348397 association,physical association anti tag coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
PPP6R3 MOB1B 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP6R3 ACAD11 25348397 N/A physical interaction ComPPI
PPP6R3 ANKRD44 25348397 N/A physical interaction ComPPI
PPP6R3 ANKRD52 25348397 N/A physical interaction ComPPI
PPP6R3 DNAJC11 25348397 N/A physical interaction ComPPI
PPP6R3 ERLIN2 25348397 N/A physical interaction ComPPI
PPP6R3 PPP6R1 18186651 24234451 25348397 association chromatography technology,physical interaction ComPPI,IntAct
PPP6R3 ETFA 25348397 N/A physical interaction ComPPI
PPP6R3 HSP90AA2P 25348397 N/A physical interaction ComPPI
PPP6R3 TPM1 25348397 N/A physical interaction ComPPI
PPP6R3 UNK 25348397 N/A physical interaction ComPPI
PPP6R3 NSUN5 25348397 N/A physical interaction ComPPI
PPP6R3 TIPRL 25348397 N/A physical interaction ComPPI
PPP6R3 ZNRF2 25348397 N/A physical interaction ComPPI
PPP6R3 ZNF746 25348397 N/A physical interaction ComPPI
PPP6R3 TRMT2A 25348397 N/A physical interaction ComPPI
PPP6R3 STK40 25348397 N/A physical interaction ComPPI
PPP6R3 TNIP3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B5DD3 PPP6R3 27087310 direct interaction,inhibition N/A NPInter

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