GENE：PRICKLE2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PRICKLE2 |
| FullNmae | prickle planar cell polarity protein 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20340 |
| EnsembleID | ENSG00000163637 |
| Uniprot | Q7Z3G6 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PRICKLE2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PRICKLE2 | GO:0005737,GO:0008270,GO:0031965,GO:0060071 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PRICKLE2 | hsa:166336 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PRICKLE2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | PRICKLE2 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | PRICKLE2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CEBPA | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | PRICKLE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | PRICKLE2 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000009262D | PRICKLE2 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00004ACAAA | PRICKLE2 | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000527B00 | PRICKLE2 | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | PRICKLE2 | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | PRICKLE2 | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | PRICKLE2 | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | PRICKLE2 | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | PRICKLE2 | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CCBB9 | PRICKLE2 | 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004505E4 | PRICKLE2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017EA6A | PRICKLE2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | PRICKLE2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006F90B | PRICKLE2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | PRICKLE2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | PRICKLE2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SMURF2 | PRICKLE2 | 14525934 19379695 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| PARP2 | PRICKLE2 | 21812934 24234451 25348397 | adp ribosylation reaction | protein array | ComPPI,IntAct |
| PRICKLE2 | APP | 25348397 | N/A | physical interaction | ComPPI |
| PRICKLE2 | USP9X | 25348397 | N/A | physical interaction | ComPPI |