Gene Information gene info

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GENE：PTPN21

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPN21
FullNmae protein tyrosine phosphatase non-receptor type 21
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9651
EnsembleID ENSG00000070778
Uniprot Q16825

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPN21 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTPN21 GO:0004725,GO:0005515,GO:0005737,GO:0005856,GO:0006470

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PTPN21 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PTPN21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTPN21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTPN21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PTPN21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTPN21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTPN21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PTPN21 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 PTPN21 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
BMX PTPN21 25361965 interaction type N/A PTMCode2
PTPN21 BMX 25361965 interaction type N/A PTMCode2
PTPN21 SRC 25361965 interaction type N/A PTMCode2
SRC PTPN21 25361965 interaction type N/A PTMCode2
PTPN21 TEC 25361965 interaction type N/A PTMCode2
TEC PTPN21 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAGOHB PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CATSPER1 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBASH3B PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAG3 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOT PTPN21 25348397 N/A physical interaction ComPPI
MOB3C PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FBXO17 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VBP1 PTPN21 25348397 N/A physical interaction ComPPI
PFDN4 PTPN21 25348397 N/A physical interaction ComPPI
PAK5 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TEC PTPN21 11013262 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SRC PTPN21 14525934 15143158 24234451 25348397 7519780 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RHPN1 PTPN21 25348397 N/A physical interaction ComPPI
WWP1 PTPN21 25348397 N/A physical interaction ComPPI
TRIP6 PTPN21 25348397 N/A physical interaction ComPPI
CSNK2A1 PTPN21 25348397 N/A physical interaction ComPPI
AKAP1 PTPN21 14525934 15143158 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
AKR7A2 PTPN21 25348397 N/A physical interaction ComPPI
DUSP7 PTPN21 25348397 N/A physical interaction ComPPI
PARD6B PTPN21 25348397 N/A physical interaction ComPPI
WWC1 PTPN21 25348397 N/A physical interaction ComPPI
RMND5A PTPN21 25348397 N/A physical interaction ComPPI
QARS1 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSNK2A2 PTPN21 25348397 N/A physical interaction ComPPI
SNX18 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STXBP4 PTPN21 25348397 N/A physical interaction ComPPI
BMX PTPN21 11013262 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
YAP1 PTPN21 25348397 N/A physical interaction ComPPI
PTPN21 KIF1C 14525934 25348397 27898060 9685376 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PTPN21 AJUBA 25348397 N/A physical interaction ComPPI
PTPN21 LPP 25348397 N/A physical interaction ComPPI
PTPN21 PFDN6 25348397 N/A physical interaction ComPPI
PTPN21 USP9X 25348397 N/A physical interaction ComPPI
PTPN21 WWC2 25348397 N/A physical interaction ComPPI
PTPN21 NEK7 25348397 N/A physical interaction ComPPI
PTPN21 PM20D2 25348397 N/A physical interaction ComPPI
PTPN21 IFT52 25348397 N/A physical interaction ComPPI
PTPN21 TTC26 25348397 N/A physical interaction ComPPI
PTPN21 DCAF8 25348397 N/A physical interaction ComPPI
PTPN21 POLR1B 25348397 N/A physical interaction ComPPI
PTPN21 WDR26 25348397 N/A physical interaction ComPPI
PTPN21 AHCYL2 25348397 N/A physical interaction ComPPI
PTPN21 BPIFB1 25348397 N/A physical interaction ComPPI
PTPN21 NAF1 25348397 N/A physical interaction ComPPI
PTPN21 ARMC8 25348397 N/A physical interaction ComPPI
PTPN21 DCAF5 25348397 N/A physical interaction ComPPI
PTPN21 ELP2 25348397 N/A physical interaction ComPPI
PTPN21 ACAD8 25348397 N/A physical interaction ComPPI
PTPN21 AHCYL1 25348397 N/A physical interaction ComPPI
PTPN21 POLR1C 25348397 N/A physical interaction ComPPI
PTPN21 TMX3 25348397 N/A physical interaction ComPPI
PTPN21 CDK4 25348397 N/A physical interaction ComPPI
PTPN21 DNAJB11 25348397 N/A physical interaction ComPPI
PTPN21 NDUFA9 25348397 N/A physical interaction ComPPI
PTPN21 TRIM14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN21 VPS26C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN21 FAM214B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN21 RASD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN21 CWC22 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WDR5 PTPN21 25348397 N/A physical interaction ComPPI
ZNF497 PTPN21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN21 SRC 15143158 27898060 7519780 stimulant N/A OmniPath

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