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GENE：TFAP4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TFAP4
FullNmae transcription factor AP-4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11745
EnsembleID ENSG00000090447
Uniprot Q01664

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TFAP4 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TFAP4 GO:0000785,GO:0000976,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0001228,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005739,GO:0006357,GO:0006978,GO:0008285,GO:0010629,GO:0017053,GO:0042803,GO:0042826,GO:0043065,GO:0043392,GO:0043565,GO:0043922,GO:0043922,GO:0043923,GO:0045736,GO:0045892,GO:0045892,GO:0045893,GO:0045944,GO:0065003,GO:0070888,GO:0071549,GO:1901990,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TFAP4 hsa:7023 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 TFAP4 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 TFAP4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 TFAP4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 TFAP4 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C TFAP4 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TFAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC TFAP4 19270520 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 TFAP4 N/A 15685193 rna interference,inhibition array technology miRSponge
URS0000508C13 TFAP4 15685193 20371350 21572407 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,clip TarBase
URS0000237AF9 TFAP4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000037D7E5 TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000B0E50 TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BCD9C TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 TFAP4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000019907A TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000137EDE TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005FDE70 TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004D84DB TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000419B5A TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000045ED38 TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027F5F3 TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000759B6A TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F9738 TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F373E TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C TFAP4 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TEKT4 TFAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM TFAP4 16924111 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GOLGA2 TFAP4 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TFAP4 EXOSC8 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TFAP4 FBXW11 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TFAP4 ELAVL1 25348397 N/A physical interaction ComPPI
TFAP4 CLOCK 25348397 N/A physical interaction ComPPI
TFAP4 USF2 25348397 N/A physical interaction ComPPI
TFAP4 NFATC2 25348397 N/A physical interaction ComPPI
TFAP4 TFCP2 25348397 N/A physical interaction ComPPI
TFAP4 GTF2I 25348397 N/A physical interaction ComPPI
TFAP4 UBP1 25348397 N/A physical interaction ComPPI
TFAP4 NR2F1 25348397 N/A physical interaction ComPPI
TFAP4 NR2F2 25348397 N/A physical interaction ComPPI
TFAP4 NFIC 25348397 N/A physical interaction ComPPI
TFAP4 NR2F6 25348397 N/A physical interaction ComPPI
TFAP4 PKNOX1 25348397 N/A physical interaction ComPPI
TFAP4 SP1 25348397 N/A physical interaction ComPPI
TFAP4 BRCA1 25348397 N/A physical interaction ComPPI
TFAP4 ZHX3 25348397 N/A physical interaction ComPPI
TFAP4 ZBTB7B 25348397 N/A physical interaction ComPPI
TFAP4 SP3 25348397 N/A physical interaction ComPPI
TFAP4 ESRRA 25348397 N/A physical interaction ComPPI
TFAP4 APEX1 25348397 N/A physical interaction ComPPI
TFAP4 TERF2IP 25348397 N/A physical interaction ComPPI
TFAP4 TOPBP1 25348397 N/A physical interaction ComPPI
TFAP4 MDC1 25348397 N/A physical interaction ComPPI
TFAP4 HMGB2 25348397 N/A physical interaction ComPPI
TFAP4 POLE2 25348397 N/A physical interaction ComPPI
TFAP4 HMGB1 25348397 N/A physical interaction ComPPI
TFAP4 PCNA 25348397 N/A physical interaction ComPPI
TFAP4 PARP2 25348397 N/A physical interaction ComPPI
TFAP4 TERF2 25348397 N/A physical interaction ComPPI
TFAP4 RAD50 25348397 N/A physical interaction ComPPI
TFAP4 ZBTB7A 25348397 N/A physical interaction ComPPI
TFAP4 CTBP1 25348397 N/A physical interaction ComPPI
TFAP4 WIZ 25348397 N/A physical interaction ComPPI
TFAP4 CTCF 25348397 N/A physical interaction ComPPI
TFAP4 SIN3B 25348397 N/A physical interaction ComPPI
TFAP4 MBD2 25348397 N/A physical interaction ComPPI
TFAP4 SMARCB1 25348397 N/A physical interaction ComPPI
TFAP4 ARID1A 25348397 N/A physical interaction ComPPI
TFAP4 SMARCC2 25348397 N/A physical interaction ComPPI
TFAP4 SMARCE1 25348397 N/A physical interaction ComPPI
TFAP4 ARID2 25348397 N/A physical interaction ComPPI
TFAP4 EHMT1 25348397 N/A physical interaction ComPPI
TFAP4 EHMT2 25348397 N/A physical interaction ComPPI
TFAP4 HDAC1 25348397 N/A physical interaction ComPPI
TFAP4 HDAC2 25348397 N/A physical interaction ComPPI
TFAP4 BTAF1 25348397 N/A physical interaction ComPPI
TFAP4 VRK1 25348397 N/A physical interaction ComPPI
TFAP4 BRD7 25348397 N/A physical interaction ComPPI
TFAP4 CHRAC1 25348397 N/A physical interaction ComPPI
TFAP4 S100A8 25348397 N/A physical interaction ComPPI
TFAP4 ZNF335 25348397 N/A physical interaction ComPPI
TFAP4 UHRF2 25348397 N/A physical interaction ComPPI
TFAP4 PRDM16 25348397 N/A physical interaction ComPPI
TFAP4 INO80E 25348397 N/A physical interaction ComPPI
TFAP4 PPP6R3 25348397 N/A physical interaction ComPPI
TFAP4 RAN 25348397 N/A physical interaction ComPPI
TFAP4 CABIN1 25348397 N/A physical interaction ComPPI
TFAP4 CKAP5 25348397 N/A physical interaction ComPPI
TFAP4 NGEF 25348397 N/A physical interaction ComPPI
TFAP4 DDX39B 25348397 N/A physical interaction ComPPI
TFAP4 TP53 25348397 N/A physical interaction ComPPI
TFAP4 XRCC5 25348397 N/A physical interaction ComPPI
TFAP4 BTRC 25348397 N/A physical interaction ComPPI
TFAP4 SKP1 25348397 N/A physical interaction ComPPI
TFAP4 CUL1 25348397 N/A physical interaction ComPPI
TFAP4 TRAF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TFAP4 SNRNP200 25348397 N/A physical interaction ComPPI
TFAP4 BPTF 25348397 N/A physical interaction ComPPI
TFAP4 PDE9A 25348397 N/A physical interaction ComPPI
TFAP4 RBPJ 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TFAP4 FOXA1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TFAP4 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TFAP4 ADAMTS4 25348397 N/A physical interaction ComPPI
TFAP4 HIRA 25348397 N/A physical interaction ComPPI
TFAP4 TRIB2 25348397 N/A physical interaction ComPPI
TFAP4 CTC1 25348397 N/A physical interaction ComPPI
TFAP4 AP5Z1 25348397 N/A physical interaction ComPPI
TFAP4 FOXK1 25348397 N/A physical interaction ComPPI
TFAP4 WDR45B 25348397 N/A physical interaction ComPPI
TFAP4 ARRB2 25348397 N/A physical interaction ComPPI
TFAP4 ATF1 25348397 N/A physical interaction ComPPI
TFAP4 SIN3A 25348397 N/A physical interaction ComPPI
TFAP4 GNB4 25348397 N/A physical interaction ComPPI
TFAP4 HNRNPL 25348397 N/A physical interaction ComPPI
TFAP4 HDAC3 16924111 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TFAP4 PRDM5 24234451 25348397 25416956 physical association bimolecular fluorescence complementation ComPPI,IntAct
TFAP4 AIM2 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
TFAP4 PTPN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFAP4 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFAP4 AJUBA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFAP4 TRAF4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFAP4 MCRS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFAP4 MAD2L2 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
TFAP4 HDAC1 19505873 27898060 stimulant N/A OmniPath
TFAP4 SP1 19505873 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B471D TFAP4 27087310 direct interaction,inhibition N/A NPInter

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