GENE:TFDP2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TFDP2 |
| FullNmae | transcription factor Dp-2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11751 |
| EnsembleID | ENSG00000114126 |
| Uniprot | Q14188 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TFDP2 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TFDP2 | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TFDP2 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TFDP2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TFDP2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TFDP2 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TFDP2 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TFDP2 | GO:0000785,GO:0000977,GO:0000977,GO:0000981,GO:0000981,GO:0001228,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006357,GO:0007049,GO:0007507,GO:0008134,GO:0019904,GO:0045892,GO:0045944,GO:0051726,GO:0072686,GO:0090575 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| TFDP2 | hsa:7029 | path:hsa04110 | Cell cycle - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TFDP2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | TFDP2 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | TFDP2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TFDP2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TFDP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003E1A9 | TFDP2 | 20053927 | rna interference,inhibition | western blot | miRSponge |
| URS000003E1A9 | TFDP2 | 20053927 25416803 | mrna cleavage,inhibition | western blot | TarBase |
| URS0000029EBD | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | TFDP2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000215483 | TFDP2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031F6C2 | TFDP2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | TFDP2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | TFDP2 | 21572407 23313552 23592263 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | TFDP2 | 22927820 23313552 23592263 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | TFDP2 | 22927820 23313552 23592263 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | TFDP2 | 22927820 23313552 23592263 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000032835F | TFDP2 | 22927820 23313552 23592263 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | TFDP2 | 22927820 23313552 23592263 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | TFDP2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | TFDP2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F4AC3 | TFDP2 | 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | TFDP2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021202F | TFDP2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000753AD | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027464B | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DC1D3 | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000156390 | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D986D | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000345DEB | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | TFDP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C1E1 | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032AE90 | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5ECC | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0B46 | TFDP2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000458AD2 | TFDP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000239117 | TFDP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0874 | TFDP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000083D87 | TFDP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000057FDB8 | TFDP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000078918 | TFDP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | TFDP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B0F6 | TFDP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | TFDP2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000008A99 | TFDP2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000367985 | TFDP2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F31F4 | TFDP2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000048D44E | TFDP2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000086A4D | TFDP2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000221168 | TFDP2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CC20C | TFDP2 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LIN37 | TFDP2 | 17531812 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| E2F6 | TFDP2 | 16189514 21516116 24234451 25348397 25416956 27705803 | association,physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| RYBP | TFDP2 | 25348397 | N/A | physical interaction | ComPPI |
| RB1 | TFDP2 | 16360038 24234451 25348397 | physical association | coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| RBL2 | TFDP2 | 17531812 24234451 25348397 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| E2F1 | TFDP2 | 14525934 25348397 8755520 9368098 | N/A | two hybrid,experimental interaction detection,physical interaction,comigration in non denaturing gel electrophoresis,in vivo,two hybrid | ComPPI,HPRD |
| E2F4 | TFDP2 | 10090723 14525934 16360038 24234451 25348397 | physical association | experimental interaction detection,isothermal titration calorimetry,x-ray crystallography,physical interaction,in vitro | ComPPI,HPRD,IntAct |
| LIN9 | TFDP2 | 17531812 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| E2F5 | TFDP2 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAE | TFDP2 | 14525934 16482218 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| TFDP2 | RBL1 | 25348397 | N/A | coimmunoprecipitation,physical interaction,physical interaction | ComPPI |
| TFDP2 | E2F3 | 14525934 25348397 7739537 8755520 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
| TFDP2 | PCGF6 | 24234451 25348397 27705803 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| TFDP2 | L3MBTL2 | 25348397 | N/A | physical interaction | ComPPI |
| TFDP2 | GMCL1 | 27898060 9878064 | N/A | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B39E1 | TFDP2 | 27087310 | direct interaction,inhibition | N/A | NPInter |
