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GENE：SERINC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SERINC3
FullNmae serine incorporator 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11699
EnsembleID ENSG00000132824
Uniprot Q13530

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SERINC3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SERINC3 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SERINC3 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SERINC3 GO:0000139,GO:0005515,GO:0005886,GO:0006564,GO:0009597,GO:0015194,GO:0015825,GO:0016020,GO:0045087,GO:0048471,GO:0051607,GO:1902237

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SERINC3 hsa:10955 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SERINC3 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR SERINC3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SERINC3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXA1 SERINC3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SERINC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SERINC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SERINC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SERINC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SERINC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000029D9F1 SERINC3 21282569 rna interference,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000029D9F1 SERINC3 21282569 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002C0FCB SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00003D5391 SERINC3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000044FD7 SERINC3 24039954 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003CCBB9 SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD231 SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 SERINC3 20371350 21572407 23313552 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 SERINC3 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002DD349 SERINC3 20371350 21572407 23313552 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED SERINC3 20371350 21572407 23313552 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 SERINC3 20371350 21572407 23313552 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000042B108 SERINC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001B0D1E SERINC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 SERINC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 SERINC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A SERINC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F SERINC3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D SERINC3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 SERINC3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A SERINC3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000005D4F5 SERINC3 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RPS15 SERINC3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
XPO5 SERINC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
VDAC2 SERINC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PHB2 SERINC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC16A1 SERINC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ELAVL1 SERINC3 25348397 N/A physical interaction ComPPI
HACD3 SERINC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
VDAC3 SERINC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KDELR1 SERINC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SERINC3 SURF4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SERINC3 KDELR2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SERINC3 BMP10 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AGTR1 SERINC3 24234451 28298427 physical association ubiquitin reconstruction IntAct
SERINC3 DRD2 24234451 28298427 physical association ubiquitin reconstruction IntAct
TRIM28 SERINC3 24234451 30021884 physical association cross-linking study IntAct

Visualization










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