Gene Information gene info

  1. Home

GENE：SH2D1B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SH2D1B
FullNmae SH2 domain containing 1B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30416
EnsembleID ENSG00000198574
Uniprot O14796

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SH2D1B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SH2D1B GO:0002250,GO:0002366,GO:0002717,GO:0005515,GO:0005829,GO:0030674,GO:0045087,GO:0045089

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SH2D1B hsa:117157 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SH2D1B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 SH2D1B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SH2D1B 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SH2D1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SH2D1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SH2D1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SH2D1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SH2D1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SH2D1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SH2D1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SH2D1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FLI1 SH2D1B N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SH2D1B LY9 25361965 interaction type N/A PTMCode2
LY9 SH2D1B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAGEB4 SH2D1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AGR2 SH2D1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ERBB2 SH2D1B 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
PTPN18 SH2D1B 23322602 24234451 25348397 association pull down ComPPI,IntAct
PECAM1 SH2D1B 23322602 24234451 25348397 association pull down ComPPI,IntAct
KIT SH2D1B 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SLAMF1 SH2D1B 10549287 11689425 14525934 24234451 25348397 association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
INPP5D SH2D1B 23322602 24234451 25348397 association pull down ComPPI,IntAct
PLCG2 SH2D1B 24234451 24642916 25348397 association pull down,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
AR SH2D1B 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
STAT4 SH2D1B 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
GAB1 SH2D1B 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
HSPA1A SH2D1B 25348397 N/A physical interaction ComPPI
HSPA1B SH2D1B 25348397 N/A physical interaction ComPPI
PRDX1 SH2D1B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SLAMF6 SH2D1B 16920955 23346089 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
MAPK8IP2 SH2D1B 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MET SH2D1B 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
TGFB1I1 SH2D1B 23322602 24234451 25348397 association pull down ComPPI,IntAct
SH2D1A SH2D1B 16920955 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CD84 SH2D1B 11689425 12115647 12928397 14525934 23322602 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
SLAMF7 SH2D1B 24234451 24642916 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
CD244 SH2D1B 11689425 14525934 23346089 24234451 24642916 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,surface plasmon resonance,in vitro,in vivo,surface plasmon resonance array,two hybrid ComPPI,HPRD,IntAct
LY9 SH2D1B 11689425 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SH2D1B APP 25348397 N/A physical interaction ComPPI
SH2D1B TRIM54 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH2D1B OLIG1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping ComPPI,IntAct
SH2D1B PTK2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SH2D1B DAPP1 23322602 24234451 25348397 association pull down ComPPI,IntAct
SH2D1B PLCG1 24234451 24642916 25348397 association pull down,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
SH2D1B NFKBID 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

Visualization










  Return