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GENE：SHKBP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SHKBP1
FullNmae SH3KBP1 binding protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19214
EnsembleID ENSG00000160410
Uniprot Q8TBC3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SHKBP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SHKBP1 GO:0005515,GO:0005764,GO:0042802,GO:0045742,GO:0045742,GO:0051260

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SHKBP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SHKBP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SHKBP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 SHKBP1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF SHKBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SHKBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 SHKBP1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 SHKBP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FHL3 SHKBP1 25348397 N/A physical interaction ComPPI
SH3KBP1 SHKBP1 11152963 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TNFAIP3 SHKBP1 25348397 N/A physical interaction ComPPI
YWHAG SHKBP1 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DCUN1D1 SHKBP1 25348397 N/A physical interaction ComPPI
WDR83 SHKBP1 25348397 N/A physical interaction ComPPI
GRB2 SHKBP1 11152963 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
COPS5 SHKBP1 25348397 N/A physical interaction ComPPI
CUL3 SHKBP1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YWHAB SHKBP1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN4 SHKBP1 25348397 N/A physical interaction ComPPI
HNRNPL SHKBP1 25348397 N/A physical interaction ComPPI
XPO1 SHKBP1 25348397 N/A physical interaction ComPPI
NEDD8 SHKBP1 25348397 N/A physical interaction ComPPI
PDZK1 SHKBP1 25348397 N/A physical interaction ComPPI
TENT5A SHKBP1 25348397 N/A physical interaction ComPPI
MMS19 SHKBP1 25348397 N/A physical interaction ComPPI
CCNG1 SHKBP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COPS6 SHKBP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHKBP1 COL7A1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SHKBP1 ANKRD28 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SHKBP1 UBXN1 25348397 N/A physical interaction ComPPI
SHKBP1 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SHKBP1 PTPN3 24234451 25348397 28330616 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SHKBP1 ASPSCR1 25348397 N/A physical interaction ComPPI
SHKBP1 FEM1B 25348397 N/A physical interaction ComPPI
SHKBP1 ARIH1 25348397 N/A physical interaction ComPPI
SHKBP1 UBE2M 25348397 N/A physical interaction ComPPI
SHKBP1 TRIM25 25348397 N/A physical interaction ComPPI
SHKBP1 NR3C1 25348397 N/A physical interaction ComPPI
SHKBP1 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SHKBP1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

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