GENE：SLX4IP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SLX4IP |
| FullNmae | SLX4 interacting protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16225 |
| EnsembleID | ENSG00000149346 |
| Uniprot | Q5VYV7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SLX4IP | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SLX4IP | GO:0005515 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SLX4IP | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | SLX4IP | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | SLX4IP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | SLX4IP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | SLX4IP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | SLX4IP | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SLX4IP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | SLX4IP | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | SLX4IP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | SLX4IP | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000355E82 | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B2B | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043C1C3 | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EBD4B | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC4BD | SLX4IP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RPN1 | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TP53BP1 | SLX4IP | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MAPK14 | SLX4IP | 25348397 | N/A | physical interaction | ComPPI |
| DLD | SLX4IP | 25348397 | N/A | physical interaction | ComPPI |
| PLK1 | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HNRNPL | SLX4IP | 25348397 | N/A | physical interaction | ComPPI |
| SUMO2 | SLX4IP | 25348397 | N/A | physical interaction | ComPPI |
| CUL1 | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GABARAP | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| STK4 | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MDC1 | SLX4IP | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| COPS7A | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GORASP1 | SLX4IP | 25348397 | N/A | physical interaction | ComPPI |
| BRCA1 | SLX4IP | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ATG3 | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ERCC4 | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ERCC1 | SLX4IP | 25348397 | N/A | physical interaction | ComPPI |
| GABARAPL1 | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ATG4B | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| SLX4 | SLX4IP | 19596235 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
| RNF20 | SLX4IP | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |