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GENE：SORCS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SORCS2
FullNmae sortilin related VPS10 domain containing receptor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16698
EnsembleID ENSG00000184985
Uniprot Q96PQ0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SORCS2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SORCS2 GO:0005829,GO:0006886,GO:0007218,GO:0008188,GO:0016020,GO:0031901,GO:0043197,GO:0043204,GO:0043231,GO:0055038,GO:0060292,GO:0098839

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SORCS2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 SORCS2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SORCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000183BED SORCS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000E601 SORCS2 22100165 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SORCS2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE SORCS2 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA SORCS2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A SORCS2 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E96DA SORCS2 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 SORCS2 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 SORCS2 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 SORCS2 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B7450 SORCS2 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 SORCS2 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC SORCS2 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 SORCS2 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000A939F SORCS2 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 SORCS2 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 SORCS2 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000047944F SORCS2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NGFR SORCS2 24234451 24908487 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
TRIM25 SORCS2 25348397 N/A physical interaction ComPPI
BDNF SORCS2 24234451 24908487 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
NTF3 SORCS2 24234451 24908487 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
SORCS2 HNRNPU 24234451 30021884 physical association cross-linking study IntAct

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