Gene Information gene info

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GENE：SPAST

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPAST
FullNmae spastin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11233
EnsembleID ENSG00000021574
Uniprot Q9UBP0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPAST mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SPAST immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPAST GO:0000281,GO:0000922,GO:0001578,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005768,GO:0005783,GO:0005789,GO:0005811,GO:0005813,GO:0005829,GO:0005829,GO:0005874,GO:0006888,GO:0007084,GO:0007409,GO:0008017,GO:0008089,GO:0008152,GO:0008568,GO:0008568,GO:0010458,GO:0015630,GO:0016853,GO:0016887,GO:0019896,GO:0030424,GO:0030496,GO:0030496,GO:0031117,GO:0031410,GO:0031468,GO:0031965,GO:0032467,GO:0032506,GO:0034214,GO:0043014,GO:0044877,GO:0048471,GO:0048487,GO:0048487,GO:0051013,GO:0051013,GO:0051013,GO:0051228,GO:0051260,GO:0061640,GO:0070062,GO:0090148,GO:1904115

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SPAST 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC SPAST 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SPAST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NRF1 SPAST 22574173 trascriptional regulation,stimulation inferred by curator TFlink
NFE2L1 SPAST 22574173 trascriptional regulation,stimulation inferred by curator TFlink
SOX11 SPAST 22574173 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000028BB8 SPAST 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00002FC5B0 SPAST 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 SPAST 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 SPAST 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A SPAST 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF SPAST 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB SPAST 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 SPAST 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001496AE SPAST 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHMP2A SPAST 25348397 N/A physical interaction ComPPI
VCP SPAST 25348397 N/A physical interaction ComPPI
RNF111 SPAST 25348397 N/A physical interaction ComPPI
FOSL2 SPAST 25348397 N/A physical interaction ComPPI
NUP85 SPAST 25348397 N/A physical interaction ComPPI
NUP98 SPAST 25348397 N/A physical interaction ComPPI
ELAVL1 SPAST 25348397 N/A physical interaction ComPPI
NUP133 SPAST 25348397 N/A physical interaction ComPPI
HECW2 SPAST 25348397 N/A physical interaction ComPPI
AURKB SPAST 24234451 24571573 25348397 colocalization fluorescence microscopy ComPPI,IntAct
NUP107 SPAST 25348397 N/A physical interaction ComPPI
NLRP3 SPAST 25348397 N/A physical interaction ComPPI
NUP43 SPAST 25348397 N/A physical interaction ComPPI
SPAST IST1 25348397 N/A physical interaction ComPPI
SPAST ALB 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SPAST WDR45 25348397 N/A physical interaction ComPPI
SPAST H2AC21 25348397 N/A physical interaction ComPPI

Visualization










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