Gene Information gene info

GENE:SPECC1L

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPECC1L
FullNmae sperm antigen with calponin homology and coiled-coil domains 1 like
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29022
EnsembleID ENSG00000100014
Uniprot Q69YQ0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPECC1L immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPECC1L GO:0005515,GO:0005737,GO:0005815,GO:0005819,GO:0005921,GO:0007049,GO:0007155,GO:0015629,GO:0030036,GO:0031941,GO:0051301

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SPECC1L 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SPECC1L 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SPECC1L 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SPECC1L 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SPECC1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 SPECC1L 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000FC8EB SPECC1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004505E4 SPECC1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E SPECC1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE SPECC1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003FD55 SPECC1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 SPECC1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001EFBE3 SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C11BC SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000251D0B SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C403E SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001ADE63 SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000077DDE SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002CBC6D SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EC1BE SPECC1L 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
UBE2I SPECC1L 25348397 N/A physical interaction ComPPI
SNW1 SPECC1L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1CB SPECC1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KEAP1 SPECC1L 25348397 N/A physical interaction ComPPI
VAV1 SPECC1L 25348397 N/A physical interaction ComPPI
GRB2 SPECC1L 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN SPECC1L 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PPP1R12A SPECC1L 24234451 25348397 28330616 association pull down ComPPI,IntAct
FEZ1 SPECC1L 25348397 N/A physical interaction ComPPI
UBC SPECC1L 25348397 N/A physical interaction ComPPI
APC SPECC1L 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
YBX1 SPECC1L 24234451 25348397 25497084 association anti bait coimmunoprecipitation ComPPI,IntAct
NFKBIA SPECC1L 25348397 N/A physical interaction ComPPI
IQGAP1 SPECC1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CFTR SPECC1L 25348397 N/A physical interaction ComPPI
PDLIM7 SPECC1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2 SPECC1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MDC1 SPECC1L 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
RIPK3 SPECC1L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
LPXN SPECC1L 25348397 N/A physical interaction ComPPI
DUSP22 SPECC1L 25348397 N/A physical interaction ComPPI
AP2M1 SPECC1L 25348397 N/A physical interaction ComPPI
ELOA SPECC1L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SYNPO SPECC1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RCN1 SPECC1L 25348397 N/A physical interaction ComPPI
PAN2 SPECC1L 25348397 N/A physical interaction ComPPI
SPC25 SPECC1L 25348397 N/A physical interaction ComPPI
MYH9 SPECC1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KCTD17 SPECC1L 25348397 N/A physical interaction ComPPI
DBN1 SPECC1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL15 SPECC1L 25348397 N/A physical interaction ComPPI
KSR1 SPECC1L 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
GLIS2 SPECC1L 17289029 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FBXO25 SPECC1L 25348397 N/A physical interaction ComPPI
CAPZA2 SPECC1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
G3BP1 SPECC1L 25348397 N/A physical interaction ComPPI
PLEKHA7 SPECC1L 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
SPECC1L ATMIN 25348397 N/A physical interaction ComPPI

Visualization