GENE:SPECC1L
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SPECC1L |
FullNmae | sperm antigen with calponin homology and coiled-coil domains 1 like |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:29022 |
EnsembleID | ENSG00000100014 |
Uniprot | Q69YQ0 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SPECC1L | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
SPECC1L | GO:0005515,GO:0005737,GO:0005815,GO:0005819,GO:0005921,GO:0007049,GO:0007155,GO:0015629,GO:0030036,GO:0031941,GO:0051301 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | SPECC1L | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | SPECC1L | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | SPECC1L | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | SPECC1L | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | SPECC1L | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000003ABC4 | SPECC1L | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000FC8EB | SPECC1L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00004505E4 | SPECC1L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000035CC3E | SPECC1L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00005651EE | SPECC1L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000003FD55 | SPECC1L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000021D7C8 | SPECC1L | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00001EFBE3 | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001C11BC | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000251D0B | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00000C403E | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001ADE63 | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000077DDE | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002CBC6D | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000355E82 | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00000EC1BE | SPECC1L | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
UBE2I | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
SNW1 | SPECC1L | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
PPP1CB | SPECC1L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
KEAP1 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
VAV1 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
GRB2 | SPECC1L | 12577067 24234451 25348397 | association | pull down | ComPPI,IntAct |
JUN | SPECC1L | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
PPP1R12A | SPECC1L | 24234451 25348397 28330616 | association | pull down | ComPPI,IntAct |
FEZ1 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
UBC | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
APC | SPECC1L | 20936779 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
YBX1 | SPECC1L | 24234451 25348397 25497084 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
NFKBIA | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
IQGAP1 | SPECC1L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CFTR | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
PDLIM7 | SPECC1L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDK2 | SPECC1L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MDC1 | SPECC1L | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
RIPK3 | SPECC1L | 14743216 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
LPXN | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
DUSP22 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
AP2M1 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
ELOA | SPECC1L | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
SYNPO | SPECC1L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
RCN1 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
PAN2 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
SPC25 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
MYH9 | SPECC1L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
KCTD17 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
DBN1 | SPECC1L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
RPL15 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
KSR1 | SPECC1L | 24234451 25348397 27086506 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
GLIS2 | SPECC1L | 17289029 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
FBXO25 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
CAPZA2 | SPECC1L | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
G3BP1 | SPECC1L | 25348397 | N/A | physical interaction | ComPPI |
PLEKHA7 | SPECC1L | 24234451 25348397 28877994 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
SPECC1L | ATMIN | 25348397 | N/A | physical interaction | ComPPI |