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GENE：SSB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SSB
FullNmae small RNA binding exonuclease protection factor La
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11316
EnsembleID ENSG00000138385
Uniprot P05455

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SSB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SSB GO:0000049,GO:0000781,GO:0001682,GO:0003723,GO:0003723,GO:0003729,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005829,GO:0006400,GO:0006409,GO:0008033,GO:0008033,GO:0008266,GO:0008334,GO:0010494,GO:0042780,GO:0045727,GO:0071045,GO:0075522,GO:1903608,GO:1990825,GO:1990904

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SSB hsa:6741 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SSB XIAP 10848591 12482981 17287399 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,nucleic acid uv cross-linking assay InnateDB
GZMB SSB 16178869 17945310 23180781 protein cleavage protease assay InnateDB
GZMH SSB 19039329 23180781 protein cleavage protease assay InnateDB
GZMK SSB 19039329 23180781 protein cleavage protease assay InnateDB
EIF2AK2 SSB 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 SSB 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 SSB 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 SSB 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR SSB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SSB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC SSB N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 SSB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 SSB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB SSB 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 SSB 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 SSB 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 SSB 22135298 phosphorylation N/A PhosphoSite
SSB NCL 25361965 interaction type N/A PTMCode2
NCL SSB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNRPB2 SSB 25348397 N/A physical interaction ComPPI
IFIT3 SSB 21642987 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SNRPA1 SSB 25348397 N/A physical interaction ComPPI
EMD SSB 25348397 N/A physical interaction ComPPI
TRAF6 SSB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GABARAPL2 SSB 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
XIAP SSB 25348397 N/A physical interaction ComPPI
BMI1 SSB 25348397 N/A physical interaction ComPPI
KEAP1 SSB 25348397 N/A physical interaction ComPPI
NIFK SSB 25348397 N/A physical interaction ComPPI
MAP1LC3B SSB 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
VBP1 SSB 25348397 N/A physical interaction ComPPI
JUN SSB 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
HMGA1 SSB 25348397 N/A filter binding,physical interaction ComPPI
SPIB SSB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
COPS5 SSB 25348397 N/A physical interaction ComPPI
TPM2 SSB 25348397 N/A physical interaction ComPPI
SPP1 SSB 25348397 N/A physical interaction ComPPI
PAXIP1 SSB 25348397 N/A physical interaction ComPPI
CUL3 SSB 25348397 N/A physical interaction ComPPI
YWHAZ SSB 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
UBC SSB 25348397 N/A physical interaction ComPPI
NTRK1 SSB 25348397 N/A physical interaction ComPPI
YBX1 SSB 23986595 24234451 25348397 association,physical association anti tag coimmunoprecipitation ComPPI,IntAct
EIF2AK2 SSB 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLE SSB 25348397 N/A physical interaction ComPPI
CSNK2A1 SSB 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
EEF1A1 SSB 25348397 N/A physical interaction ComPPI
ANP32A SSB 25348397 N/A physical interaction ComPPI
VDAC1 SSB 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PPP2CA SSB 25348397 N/A physical interaction ComPPI
EWSR1 SSB 25348397 N/A physical interaction ComPPI
RABGGTA SSB 25348397 N/A physical interaction ComPPI
RXRB SSB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RPS6 SSB 24234451 25348397 29568061 association pull down ComPPI,IntAct
HUWE1 SSB 25348397 N/A physical interaction ComPPI
EXOSC10 SSB 25348397 N/A physical interaction ComPPI
UBA2 SSB 25348397 N/A physical interaction ComPPI
NEDD8 SSB 25348397 N/A physical interaction ComPPI
CUL2 SSB 25348397 N/A physical interaction ComPPI
CUL4B SSB 25348397 N/A physical interaction ComPPI
ABI1 SSB 25348397 N/A physical interaction ComPPI
CDK2 SSB 25348397 N/A physical interaction ComPPI
CUL1 SSB 25348397 N/A physical interaction ComPPI
SOX2 SSB 25348397 N/A physical interaction ComPPI
H1-4 SSB 25348397 N/A physical interaction ComPPI
EGFR SSB 25348397 N/A physical interaction ComPPI
VHL SSB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ARFGEF1 SSB 18292223 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CTTN SSB 25348397 N/A physical interaction ComPPI
RNF2 SSB 25348397 N/A physical interaction ComPPI
GABARAP SSB 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PRKCI SSB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMC3 SSB 25348397 N/A physical interaction ComPPI
MAP3K14 SSB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
DNM1L SSB 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SSB PUF60 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SSB PMVK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SSB NCL 12096904 14525934 18292223 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct,OmniPath
SSB H2AX 25348397 N/A physical interaction ComPPI
SSB TADA2A 25348397 N/A physical interaction ComPPI
SSB HDGF 25348397 N/A physical interaction ComPPI
SSB ELAVL1 25348397 N/A physical interaction ComPPI
SSB SIRT7 25348397 N/A physical interaction ComPPI
SSB CAND1 25348397 N/A physical interaction ComPPI
SSB RO60 10785401 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SSB APP 25348397 N/A physical interaction ComPPI
SSB BARD1 25348397 N/A physical interaction ComPPI
SSB SMURF1 25348397 N/A physical interaction ComPPI
SSB FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
SSB IL7R 25348397 N/A physical interaction ComPPI
SSB CBX6 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SSB GZMH 25348397 N/A physical interaction ComPPI
SSB CSNK2B 25348397 N/A physical interaction ComPPI
SSB TARDBP 25348397 N/A physical interaction ComPPI
SSB KARS1 25348397 N/A physical interaction ComPPI
SSB NPLOC4 25348397 N/A physical interaction ComPPI
SSB LIN28A 25348397 N/A physical interaction ComPPI
SSB SUZ12 25348397 N/A physical interaction ComPPI
SSB SURF2 25348397 N/A physical interaction ComPPI
SSB HNRNPA1 25348397 N/A physical interaction ComPPI
SSB ANKMY2 25348397 N/A physical interaction ComPPI
SSB EEF1A1P5 25348397 N/A physical interaction ComPPI
SSB LARP7 25348397 N/A physical interaction ComPPI
SSB NAT10 25348397 N/A physical interaction ComPPI
SSB POLR1C 25348397 N/A physical interaction ComPPI
SSB RBM34 25348397 N/A physical interaction ComPPI
SSB CDC37 25348397 N/A physical interaction ComPPI
SSB DDX27 25348397 N/A physical interaction ComPPI
SSB DDX54 25348397 N/A physical interaction ComPPI
SSB MYH9 25348397 N/A physical interaction ComPPI
SSB NOP56 25348397 N/A physical interaction ComPPI
SSB PUS7 25348397 N/A physical interaction ComPPI
SSB RPL31 25348397 N/A physical interaction ComPPI
SSB RPS3 25348397 N/A physical interaction ComPPI
SSB SAFB2 25348397 N/A physical interaction ComPPI
SSB TRMT6 25348397 N/A physical interaction ComPPI
SSB WDR74 25348397 N/A physical interaction ComPPI
SSB CCNA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSB SNCA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSB TBC1D9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSB TRIM33 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSB ARMC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSB ATOH1 25348397 N/A physical interaction ComPPI
SSB FAN1 25348397 N/A physical interaction ComPPI
SSB PTP4A1 25348397 N/A physical interaction ComPPI
SSB TRMT2A 25348397 N/A physical interaction ComPPI
SSB PRPF31 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
SSB CYLD 25348397 N/A physical interaction ComPPI
SSB SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SSB BRCA1 25348397 N/A physical interaction ComPPI
SSB FBXO32 25348397 N/A physical interaction ComPPI
SSB PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SSB TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SSB NME2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SSB IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SSB NR3C1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SSB SCHIP1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SSB GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SSB HTR7 19486527 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SSB PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
SSB FBL 24234451 25348397 29568061 association pull down ComPPI,IntAct
H3C1 SSB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LYAR SSB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ZNF593 SSB 25348397 N/A physical interaction ComPPI
MRPL1 SSB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSB SSB 14525934 15485924 N/A experimental interaction detection HPRD
SSB DST 24234451 30021884 physical association cross-linking study IntAct
TCOF1 SSB 24234451 30021884 physical association cross-linking study IntAct
H2BC21 SSB 24234451 30021884 physical association cross-linking study IntAct
SSB OXER1 24234451 30021884 physical association cross-linking study IntAct
SSB CCDC71 24234451 30021884 physical association cross-linking study IntAct
SSB GZMB 16178869 17945310 27898060 N/A N/A OmniPath
CSNK2A1 SSB 10715123 15485924 18257391 19039329 22113938 27898060 9054510 stimulant N/A OmniPath
VRK1 SSB 10715123 15485924 27898060 9054510 N/A N/A OmniPath

Visualization










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