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GENE：SSU72

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SSU72
FullNmae SSU72 homolog, RNA polymerase II CTD phosphatase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25016
EnsembleID ENSG00000160075
Uniprot Q9NP77

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SSU72 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SSU72 GO:0005515,GO:0005654,GO:0005829,GO:0005847,GO:0006357,GO:0006369,GO:0006378,GO:0006378,GO:0008420,GO:0008420,GO:0017018

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SSU72 hsa:29101 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SSU72 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SSU72 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SSU72 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SSU72 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA SSU72 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SSU72 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SSU72 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SSU72 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SSU72 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SSU72 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SSU72 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SSU72 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 SSU72 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D SSU72 20371350 22100165 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA SSU72 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C SSU72 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D SSU72 20371350 22100165 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 SSU72 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 SSU72 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 SSU72 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 SSU72 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 SSU72 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 SSU72 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A SSU72 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 SSU72 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 SSU72 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 SSU72 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 SSU72 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E SSU72 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 SSU72 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF SSU72 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D6C3F SSU72 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A SSU72 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 SSU72 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D SSU72 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C SSU72 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 SSU72 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C770D SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000014F13C SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F1B8C SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002578DA SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005485E8 SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001919B0 SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075ABF4 SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041FA2C SSU72 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKB SSU72 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MAPK9 SSU72 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP1CB SSU72 25348397 N/A physical interaction ComPPI
SKP1 SSU72 25348397 N/A physical interaction ComPPI
RAD21 SSU72 20818333 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct
NCOA5 SSU72 25348397 N/A physical interaction ComPPI
MAPK8 SSU72 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRIO SSU72 25348397 N/A physical interaction ComPPI
PTGES3 SSU72 25348397 N/A physical interaction ComPPI
HNRNPL SSU72 25348397 N/A physical interaction ComPPI
VCL SSU72 25348397 N/A physical interaction ComPPI
XPO1 SSU72 25348397 N/A physical interaction ComPPI
H2AC18 SSU72 25348397 N/A physical interaction ComPPI
TPI1 SSU72 25348397 N/A physical interaction ComPPI
STXBP2 SSU72 25348397 N/A physical interaction ComPPI
SMC1A SSU72 20818333 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NCAPG2 SSU72 25348397 N/A physical interaction ComPPI
POLR2A SSU72 25348397 N/A physical interaction ComPPI
SMC3 SSU72 20818333 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ACAT2 SSU72 25348397 N/A physical interaction ComPPI
PRDX6 SSU72 25348397 N/A physical interaction ComPPI
CDKN2AIP SSU72 25348397 N/A physical interaction ComPPI
CSTF2 SSU72 25348397 N/A physical interaction ComPPI
CSTF3 SSU72 25348397 N/A physical interaction ComPPI
SYMPK SSU72 25348397 N/A molecular sieving,x-ray crystallography,physical interaction,physical interaction ComPPI
TRIM25 SSU72 25348397 N/A physical interaction ComPPI
UBE2H SSU72 25348397 N/A physical interaction ComPPI
THOP1 SSU72 25348397 N/A physical interaction ComPPI
ZNF638 SSU72 25348397 N/A physical interaction ComPPI
UIMC1 SSU72 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STAG2 SSU72 20818333 24234451 25348397 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CPSF1 SSU72 25348397 N/A physical interaction ComPPI
CPSF2 SSU72 25348397 N/A physical interaction ComPPI
CPSF3 SSU72 25348397 N/A physical interaction ComPPI
RRP1B SSU72 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UGGT1 SSU72 25348397 N/A physical interaction ComPPI
ELP5 SSU72 25348397 N/A physical interaction ComPPI
SEC23IP SSU72 25348397 N/A physical interaction ComPPI
FOS SSU72 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TIPRL SSU72 25348397 N/A physical interaction ComPPI
PCF11 SSU72 25348397 N/A physical interaction ComPPI
SSU72 KYNU 25348397 N/A physical interaction ComPPI
SSU72 NUDCD2 25348397 N/A physical interaction ComPPI
DNPH1 SSU72 25348397 N/A physical interaction ComPPI
LACTB2 SSU72 25348397 N/A physical interaction ComPPI
REG3A SSU72 12453421 12704082 12819204 22235117 27898060 N/A N/A OmniPath
SSU72 POLR2A 15125841 20861839 27898060 N/A N/A OmniPath
AURKB SSU72 24149858 27898060 N/A N/A OmniPath

Visualization










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