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GENE：STRADA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STRADA
FullNmae STE20 related adaptor alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30172
EnsembleID ENSG00000266173
Uniprot Q7RTN6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STRADA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
STRADA GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006611,GO:0006611,GO:0019900,GO:0030295,GO:0032147,GO:0032147,GO:0043539,GO:0043539,GO:0070314,GO:0140535,GO:1902554,GO:1902554,GO:1902554

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
STRADA hsa:92335 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
STRADA hsa:92335 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CAB39 STRADA 15509864 18687677 19197243 19942859 20160076 20484410 23030059 26192618 8910387 interaction type N/A ACSN
STK11 STRADA 15509864 18687677 19197243 19942859 20160076 20484410 23030059 26192618 8910387 interaction type N/A ACSN
DDIT4 STRADA 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
ETS1 STRADA 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TAL1 STRADA 20028976 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
STK11 STRADA 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HSP90AA1 STRADA 25348397 N/A physical interaction ComPPI
XPO1 STRADA 25348397 N/A physical interaction ComPPI
STK11 STRADA 12805220 14525934 14676191 15733851 20562859 24234451 25241761 25348397 25852190 phosphorylation reaction,colocalization,association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,protein kinase assay,in vitro,in vivo,proximity ligation assay,two hybrid ComPPI,HPRD,IntAct
CAB39 STRADA 14525934 14730349 15561763 21423148 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
STRADA HSP90AA2P 25348397 N/A physical interaction ComPPI
STRADA FBXL19 25348397 N/A physical interaction ComPPI
STRADA SHMT2 25348397 N/A physical interaction ComPPI
STRADA PIP4K2A 25348397 N/A physical interaction ComPPI
STRADA C5ORF24 25348397 N/A physical interaction ComPPI
STRADA LBHD1 25348397 N/A physical interaction ComPPI
CAB39L STRADA 25348397 N/A physical interaction ComPPI
STK11 STRADA 12805220 14676191 15561763 15733851 20562859 21860411 25241761 25852190 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BADFA STRADA 27087310 direct interaction,inhibition N/A NPInter

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