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GENE：TBC1D1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TBC1D1
FullNmae TBC1 domain family member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11578
EnsembleID ENSG00000065882
Uniprot Q86TI0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TBC1D1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TBC1D1 GO:0005096,GO:0005515,GO:0005634,GO:0090630

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TBC1D1 hsa:23216 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR TBC1D1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 TBC1D1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TBC1D1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TBC1D1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 TBC1D1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TBC1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 TBC1D1 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS000028D811 TBC1D1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001F0C23 TBC1D1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000017DBB8 TBC1D1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 TBC1D1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 TBC1D1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D TBC1D1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 TBC1D1 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 TBC1D1 22135298 phosphorylation N/A PhosphoSite
AKT1 TBC1D1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GMCL1 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXLNA TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM50B TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNNC2 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC185 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YWHAG TBC1D1 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
UBE2E2 TBC1D1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
RIN1 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CBY1 TBC1D1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SYTL4 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMAD2 TBC1D1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PNKP TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GIGYF1 TBC1D1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
YWHAB TBC1D1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPL TBC1D1 25348397 N/A physical interaction ComPPI
YWHAH TBC1D1 17979178 24234451 25348397 association tandem affinity purification ComPPI,IntAct
YWHAE TBC1D1 25348397 N/A physical interaction ComPPI
MCRS1 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPB1 TBC1D1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
MAP1LC3A TBC1D1 25348397 N/A physical interaction ComPPI
BARD1 TBC1D1 25348397 N/A physical interaction ComPPI
CGN TBC1D1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF13B TBC1D1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LNX1 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GCG TBC1D1 24234451 24239544 25348397 colocalization fluorescence microscopy ComPPI,IntAct
ZBTB21 TBC1D1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LZTS1 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KCTD3 TBC1D1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GABARAPL1 TBC1D1 25348397 N/A physical interaction ComPPI
ZFC3H1 TBC1D1 25348397 N/A physical interaction ComPPI
KSR1 TBC1D1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
VPS52 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DMBX1 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSF2BP TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOXC8 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TCEA2 TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM161A TBC1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D1 ROR1 23153538 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TBC1D1 KRT75 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D1 REXO1L1P 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D1 EFHC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D1 LHX8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D1 ZFP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D1 TSGA10IP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D1 CWF19L2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AKT1 TBC1D1 17274760 27898060 inhibition N/A OmniPath
PRKAA1 TBC1D1 17995453 27898060 inhibition N/A OmniPath

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