GENE：TEAD3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TEAD3 |
| FullNmae | TEA domain transcription factor 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11716 |
| EnsembleID | ENSG00000007866 |
| Uniprot | Q99594 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TEAD3 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TEAD3 | GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0003700,GO:0005515,GO:0005654,GO:0005667,GO:0006357,GO:0007565,GO:0035329,GO:0035329,GO:0045944,GO:0048568,GO:0055059,GO:0061629 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| TEAD3 | hsa:7005 | path:hsa04390 | Hippo signaling pathway - Homo sapiens (human) |
| TEAD3 | hsa:7005 | path:hsa04392 | Hippo signaling pathway - multiple species - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | TEAD3 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TEAD3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | TEAD3 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | TEAD3 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CEBPA | TEAD3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TEAD3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TEAD3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | TEAD3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | TEAD3 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000272039 | TEAD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000364FEF | TEAD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001799A3 | TEAD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019D79B | TEAD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB0E | TEAD3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CTBP2 | TEAD3 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| E2F1 | TEAD3 | 25348397 | N/A | physical interaction | ComPPI |
| PDHA1 | TEAD3 | 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TNIK | TEAD3 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| SUMO2 | TEAD3 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| PHB2 | TEAD3 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| HSPA4 | TEAD3 | 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| YAP1 | TEAD3 | 11358867 14525934 24234451 24255178 24366813 25348397 25751139 | colocalization,association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification,proximity-dependent biotin identification | ComPPI,HPRD,IntAct |
| VGLL2 | TEAD3 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TRIM25 | TEAD3 | 25348397 | N/A | physical interaction | ComPPI |
| WWTR1 | TEAD3 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| STUB1 | TEAD3 | 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TEAD3 | E2F3 | 25348397 | N/A | physical interaction | ComPPI |
| TEAD3 | PIDD1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| TEAD3 | MCMBP | 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FASN | TEAD3 | 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| WWTR1 | TEAD3 | 16189514 23431053 26186194 27898060 | stimulant | N/A | OmniPath |
| YAP1 | TEAD3 | 11358867 23431053 24255178 24366813 27898060 | stimulant | N/A | OmniPath |