GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
TIMM21 |
FullNmae |
translocase of inner mitochondrial membrane 21 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:25010 |
EnsembleID |
ENSG00000075336 |
Uniprot |
Q9BVV7 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
TIMM21 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
TIMM21 |
GO:0003674,GO:0005515,GO:0005743,GO:0005744,GO:0005744,GO:0005744,GO:0006886,GO:0030150,GO:0030150,GO:0032981,GO:0033617 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
TIMM21 |
20019798
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
HIF1A |
TIMM21 |
18971253
19828020
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array,inferred by curator |
TFlink |
SMARCA4 |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TP53 |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
ZNF263 |
TIMM21 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
MAD2L2 |
TIMM21 |
24234451
25348397
29656893
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
ERBB2 |
TIMM21 |
24189400
24234451
25348397
|
association |
tandem affinity purification |
ComPPI,IntAct |
TERT |
TIMM21 |
25348397
|
N/A |
physical interaction |
ComPPI |
ABCE1 |
TIMM21 |
25348397
|
N/A |
physical interaction |
ComPPI |
UBQLN2 |
TIMM21 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
TUBA1A |
TIMM21 |
24234451
25348397
29568061
|
association |
pull down |
ComPPI,IntAct |
TIMM23 |
TIMM21 |
23260140
24234451
25348397
|
association,physical association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
MT-CO1 |
TIMM21 |
23260140
24234451
25348397
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
EYA3 |
TIMM21 |
25348397
|
N/A |
physical interaction |
ComPPI |
DUSP6 |
TIMM21 |
25348397
|
N/A |
physical interaction |
ComPPI |
ESRRB |
TIMM21 |
25348397
|
N/A |
physical interaction |
ComPPI |
EYA2 |
TIMM21 |
25348397
|
N/A |
physical interaction |
ComPPI |
TIMM50 |
TIMM21 |
23260140
24234451
25348397
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
SLC25A5 |
TIMM21 |
23260140
24234451
25348397
|
association |
blue native page |
ComPPI,IntAct |
CYLD |
TIMM21 |
25348397
|
N/A |
physical interaction |
ComPPI |
COX4I1 |
TIMM21 |
23260140
24234451
25348397
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
COX6C |
TIMM21 |
23260140
24234451
25348397
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
NDUFB8 |
TIMM21 |
23260140
24234451
25348397
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
COX6B1 |
TIMM21 |
24234451
25348397
27499296
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
NDUFA4 |
TIMM21 |
25348397
|
N/A |
physical interaction |
ComPPI |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00009B9A71 |
TIMM21 |
27087310
|
direct interaction,inhibition |
N/A |
NPInter |
Visualization