GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
TMCC2 |
| FullNmae |
transmembrane and coiled-coil domain family 2 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:24239 |
| EnsembleID |
ENSG00000133069 |
| Uniprot |
O75069 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| TMCC2 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| TMCC2 |
GO:0005515,GO:0005783,GO:0005789,GO:0012505,GO:0042982,GO:0042982 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| TLE5 |
TMCC2 |
23180781
25416956
|
physical association |
two hybrid |
InnateDB |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
TMCC2 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA1 |
TMCC2 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
TMCC2 |
18971253
19941826
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| YBX1 |
TMCC2 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| FOXP3 |
TMCC2 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| SMARCA4 |
TMCC2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
TMCC2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
TMCC2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
TMCC2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
TMCC2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
TMCC2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
TMCC2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| RUNX1 |
TMCC2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000237AF9 |
TMCC2 |
18185580
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS000003ABC4 |
TMCC2 |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS000005E58C |
TMCC2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00004F4657 |
TMCC2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000004BACE |
TMCC2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000047944F |
TMCC2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00002CEB74 |
TMCC2 |
25416803
28735896
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000224AEA |
TMCC2 |
25416803
28735896
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00001012BC |
TMCC2 |
25416803
28735896
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ZNF581 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CORO1A |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FAM90A1 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CFAP206 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RHOXF2 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| DPY30 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ACTB |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CDR2 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HGS |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ZNF587 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| APOE |
TMCC2 |
21593558
24234451
25348397
27898060
|
physical association |
anti tag coimmunoprecipitation,classical fluorescence spectroscopy,two hybrid |
ComPPI,IntAct,OmniPath |
| MARK2 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TLE5 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FBLIM1 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBA1 |
TMCC2 |
14525934
16169070
24234451
25348397
|
physical association |
two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid |
ComPPI,HPRD,IntAct |
| MARK3 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| DIP2A |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UHRF1 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HNRNPLL |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| EIF4E2 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HSPD1 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| KAT5 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| AMOTL2 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TEX28 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CCDC33 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ZNF250 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ZNF417 |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| IQUB |
TMCC2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PTOV1 |
TMCC2 |
14525934
16169070
24234451
25348397
|
physical association |
two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid |
ComPPI,HPRD,IntAct |
| TMCC2 |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
| TMCC2 |
PRPF31 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TMCC2 |
FAM161A |
25348397
|
N/A |
physical interaction |
ComPPI |
| TMCC2 |
FBF1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TMCC2 |
ACTBL2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TMCC2 |
CMTR1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TMCC2 |
FKBP10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ADRB2 |
TMCC2 |
24234451
28298427
|
physical association |
ubiquitin reconstruction |
IntAct |
| SMO |
TMCC2 |
24234451
28298427
|
physical association |
ubiquitin reconstruction |
IntAct |
Visualization