GENE：TMEM126B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TMEM126B |
| FullNmae | transmembrane protein 126B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:30883 |
| EnsembleID | ENSG00000171204 |
| Uniprot | Q8IUX1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TMEM126B | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TMEM126B | GO:0003674,GO:0005515,GO:0005739,GO:0005739,GO:0005743,GO:0005743,GO:0032094,GO:0032981,GO:0032981,GO:0032981 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | TMEM126B | 11799066 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
| ETS1 | TMEM126B | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | TMEM126B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | TMEM126B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00003D5391 | TMEM126B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000002CF68 | TMEM126B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E780 | TMEM126B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027352D | TMEM126B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| DHX15 | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| MRFAP1L1 | TMEM126B | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| DHX9 | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| PDCD1 | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| ECSIT | TMEM126B | 24234451 24344204 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SUGP2 | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| NDUFA13 | TMEM126B | 24234451 24344204 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NDUFAF1 | TMEM126B | 24234451 24344204 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AIFM1 | TMEM126B | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| NDUFS1 | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| APP | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| SFXN1 | TMEM126B | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ACAD9 | TMEM126B | 24234451 24344204 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NDUFS3 | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| NDUFB11 | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| NDUFC2 | TMEM126B | 25348397 | N/A | physical interaction | ComPPI |
| TMEM126B | SCO1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |