Gene Information gene info

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GENE：SOX4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SOX4
FullNmae SRY-box transcription factor 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11200
EnsembleID ENSG00000124766
Uniprot Q06945

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SOX4 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SOX4 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SOX4 GO:0000122,GO:0000785,GO:0000976,GO:0000978,GO:0000978,GO:0000981,GO:0001228,GO:0001228,GO:0001228,GO:0001666,GO:0002328,GO:0003183,GO:0003215,GO:0003289,GO:0003357,GO:0003700,GO:0003700,GO:0005515,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005667,GO:0005737,GO:0005739,GO:0006355,GO:0007399,GO:0007507,GO:0008284,GO:0008285,GO:0009653,GO:0010467,GO:0014009,GO:0021510,GO:0021782,GO:0030154,GO:0030217,GO:0031018,GO:0031397,GO:0031647,GO:0032024,GO:0035019,GO:0035198,GO:0035910,GO:0042593,GO:0043065,GO:0043516,GO:0045588,GO:0045662,GO:0045663,GO:0045727,GO:0045893,GO:0045893,GO:0045944,GO:0045944,GO:0045944,GO:0048485,GO:0050821,GO:0060412,GO:0060485,GO:0060563,GO:0060993,GO:0061484,GO:0071333,GO:0090263,GO:1990837,GO:2000761

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SOX4 hsa:6659 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SOX4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SOX4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SOX4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 SOX4 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SOX4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ERG SOX4 24435928 trascriptional regulation,stimulation inferred by curator TFlink
KCNH2 SOX4 24435928 trascriptional regulation,stimulation inferred by curator TFlink
JUND SOX4 23482931 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002B2B5C SOX4 20924108 rna interference,inhibition array technology,rna immunoprecipitation,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS000029D9F1 SOX4 23204229 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000237AF9 SOX4 18185580 \N rna interference,inhibition array technology,experimental interaction detection,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000237AF9 SOX4 18185580 18927107 23806264 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS00002B2B5C SOX4 20924108 23505378 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,northern blot,rna immunoprecipitation,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000048F59D SOX4 19887623 20371350 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000029D9F1 SOX4 23204229 24984017 25416803 26323722 28133610 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000016C318 SOX4 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000007FBA SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00002152A8 SOX4 20371350 22473208 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000122ED0 SOX4 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002075FA SOX4 20371350 21572407 23446348 23592263 23622248 24398324 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000009262D SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 SOX4 20371350 21572407 22012620 23446348 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCDA3 SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD SOX4 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 SOX4 20371350 22473208 25201727 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000005CF5F SOX4 20371350 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 SOX4 20371350 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 SOX4 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 SOX4 20371350 21572407 22012620 22473208 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F SOX4 20371350 21572407 22012620 23446348 23592263 24398324 25416803 27084453 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS0000105D19 SOX4 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 SOX4 20371350 21572407 22012620 22473208 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B SOX4 20371350 21572407 22012620 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000053B1E8 SOX4 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000EBD4B SOX4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 SOX4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000032D69B SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E SOX4 20371350 21572407 22012620 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 SOX4 20371350 21572407 22012620 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 SOX4 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 SOX4 25416803 26823713 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000170D8B SOX4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 SOX4 23251334 25416803 mrna cleavage,inhibition array technology,western blot,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00002AAD6B SOX4 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 SOX4 20371350 21572407 22012620 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 SOX4 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 SOX4 20371350 21572407 22012620 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 SOX4 20371350 21572407 22012620 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009C45F SOX4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000450F92 SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004C5774 SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D SOX4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA SOX4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 SOX4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F SOX4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 SOX4 25416803 26252944 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS0000028BB8 SOX4 25416803 26377202 mrna cleavage,inhibition western blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001AFC71 SOX4 25416803 26377202 mrna cleavage,inhibition western blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000821E0 SOX4 25416803 27353653 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000001EB3 SOX4 25416803 25644061 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002A71AD SOX4 25416803 28412032 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
UBE2I SOX4 14525934 16631117 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TNNI3 SOX4 25348397 N/A physical interaction ComPPI
EDF1 SOX4 25348397 N/A physical interaction ComPPI
MCM6 SOX4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MCM2 SOX4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CREBBP SOX4 19234109 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EP300 SOX4 19234109 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SCNN1G SOX4 25348397 N/A physical interaction ComPPI
CTR9 SOX4 25348397 N/A physical interaction ComPPI
SDCBP SOX4 11498591 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
MDM2 SOX4 25348397 N/A physical interaction ComPPI
SOX4 TP53 19234109 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SOX4 ELAVL1 25348397 N/A physical interaction ComPPI
SOX4 TAF5 25348397 N/A physical interaction ComPPI
SOX4 IGF1 25348397 N/A physical interaction ComPPI
SOX4 FOXH1 25348397 N/A physical interaction ComPPI
SOX4 LMNB2 25348397 N/A physical interaction ComPPI
SOX4 ITIH1 25348397 N/A physical interaction ComPPI
SOX4 APOC3 25348397 N/A physical interaction ComPPI
SOX4 MNT 25348397 N/A physical interaction ComPPI
SOX4 PLXNB1 25348397 N/A physical interaction ComPPI
SOX4 BANF1 25348397 N/A physical interaction ComPPI
SOX4 RHOU 25348397 N/A physical interaction ComPPI
SOX4 USP15 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SOX4 SPAG9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SOX4 MCM4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SOX4 GATA3 22751141 24234451 25348397 27898060 physical association pull down ComPPI,IntAct,OmniPath
UBE2I SOX4 16631117 27898060 inhibition N/A OmniPath
SOX4 TCF7L2 17875931 27898060 stimulant N/A OmniPath

Visualization










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