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GENE：TOM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TOM1
FullNmae target of myb1 membrane trafficking protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11982
EnsembleID ENSG00000100284
Uniprot O60784

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TOM1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TOM1 GO:0005515,GO:0005737,GO:0005768,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0006897,GO:0007165,GO:0010008,GO:0010314,GO:0015031,GO:0016020,GO:0016020,GO:0016197,GO:0016197,GO:0016197,GO:0030276,GO:0030276,GO:0031593,GO:0031901,GO:0032050,GO:0035577,GO:0035579,GO:0043130,GO:0061753,GO:0061909,GO:0070062,GO:0070853,GO:1901098,GO:1904978

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR TOM1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 TOM1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 TOM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 TOM1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TOM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001D69F6 TOM1 18834857 20083669 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001D69F6 TOM1 18834857 20083669 22815788 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000065D58 TOM1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000153377 TOM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016FD1A TOM1 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS00000EED18 TOM1 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS00006DE17B TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002004E0 TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000024A59E TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000036AFF1 TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000005481D TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000002103A TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E TOM1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TOLLIP TOM1 25361965 interaction type N/A PTMCode2
TOM1 TOLLIP 25361965 interaction type N/A PTMCode2
CLTC TOM1 25361965 interaction type N/A PTMCode2
TOM1 CLTC 25361965 interaction type N/A PTMCode2
ZFYVE16 TOM1 25361965 interaction type N/A PTMCode2
TOM1 ZFYVE16 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
VCP TOM1 25348397 N/A physical interaction ComPPI
UBE2D1 TOM1 25348397 N/A physical interaction ComPPI
ZNF512B TOM1 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAC1 TOM1 25348397 N/A physical interaction ComPPI
HGS TOM1 15611048 24234451 25348397 physical association two hybrid ComPPI,IntAct
TOM1L1 TOM1 19798056 24234451 25348397 physical association pull down ComPPI,IntAct
UBB TOM1 25348397 N/A nuclear magnetic resonance,physical interaction ComPPI
UBC TOM1 15047686 16196087 16199040 17550899 23314748 25348397 26320582 27898060 N/A nuclear magnetic resonance,physical interaction ComPPI,OmniPath
RPS27A TOM1 25348397 N/A nuclear magnetic resonance,physical interaction ComPPI
UBA52 TOM1 25348397 N/A nuclear magnetic resonance,physical interaction ComPPI
NTRK1 TOM1 25348397 N/A physical interaction ComPPI
HNRNPL TOM1 25348397 N/A physical interaction ComPPI
EEA1 TOM1 14525934 14613930 24234451 25348397 physical association cosedimentation through density gradient,experimental interaction detection ComPPI,HPRD,IntAct
XPO1 TOM1 25348397 N/A physical interaction ComPPI
TBCD TOM1 25348397 N/A physical interaction ComPPI
CLTC TOM1 14525934 14563850 15657082 16412388 25348397 27898060 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
H1-4 TOM1 25348397 N/A physical interaction ComPPI
YAP1 TOM1 25348397 N/A physical interaction ComPPI
WDR12 TOM1 25348397 N/A physical interaction ComPPI
TSG101 TOM1 25348397 N/A physical interaction ComPPI
MYO6 TOM1 23023224 24234451 25348397 association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PRKN TOM1 25348397 N/A physical interaction ComPPI
TOLLIP TOM1 14525934 14563850 24234451 25348397 25416956 physical association coimmunoprecipitation,cosedimentation in solution,experimental interaction detection,nuclear magnetic resonance,physical interaction,two hybrid array,surface plasmon resonance array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
EXOSC4 TOM1 25348397 N/A physical interaction ComPPI
NEDD4 TOM1 25348397 N/A physical interaction ComPPI
SMURF1 TOM1 25348397 N/A physical interaction ComPPI
GARS1 TOM1 25348397 N/A physical interaction ComPPI
LITAF TOM1 25348397 N/A physical interaction ComPPI
ZFYVE16 TOM1 14613930 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,cosedimentation through density gradient,pull down,physical interaction ComPPI,IntAct
SSBP2 TOM1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTBP2 TOM1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL1R1 TOM1 25348397 N/A physical interaction ComPPI
ILVBL TOM1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPS27 TOM1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DOHH TOM1 25348397 N/A physical interaction ComPPI
MAP3K1 TOM1 25348397 N/A physical interaction ComPPI
APP TOM1 25348397 N/A physical interaction ComPPI
TOM1 ME1 25348397 N/A physical interaction ComPPI
TOM1 DDI2 25348397 N/A physical interaction ComPPI
TOM1 MYO19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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