GENE：TRDN
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TRDN |
| FullNmae | triadin |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:12261 |
| EnsembleID | ENSG00000186439 |
| Uniprot | Q13061 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TRDN | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TRDN | GO:0005102,GO:0005515,GO:0005654,GO:0005783,GO:0005829,GO:0005886,GO:0005886,GO:0006874,GO:0006936,GO:0009617,GO:0010649,GO:0010880,GO:0010880,GO:0014701,GO:0014701,GO:0014701,GO:0014808,GO:0016020,GO:0016529,GO:0030314,GO:0030674,GO:0031122,GO:0033017,GO:0033018,GO:0044325,GO:0051279,GO:0051649,GO:0060047,GO:0060047,GO:0060315,GO:0060316,GO:0060316,GO:0060316,GO:0086036,GO:0086036,GO:0090158,GO:1901846 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| TRDN | hsa:10345 | path:hsa04020 | Calcium signaling pathway - Homo sapiens (human) |
| TRDN | hsa:10345 | path:hsa04260 | Cardiac muscle contraction - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA2 | TRDN | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| PRDM14 | TRDN | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TRDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TRDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TRDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TRDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TRDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TRDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TRDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | TRDN | 18185580 19536157 25416803 | mrna cleavage,inhibition | array technology,clip | TarBase |
| URS0000521626 | TRDN | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000040EC3B | TRDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004CCA62 | TRDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | TRDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | TRDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | TRDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001919B0 | TRDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000544FF1 | TRDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEE35 | TRDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SOCS3 | TRDN | 25348397 | N/A | physical interaction | ComPPI |
| CALM1 | TRDN | 25348397 | N/A | physical interaction | ComPPI |
| EMC2 | TRDN | 25348397 | N/A | physical interaction | ComPPI |
| RYR1 | TRDN | 10212196 10531621 11069905 14525934 14638677 25348397 27898060 7721813 9287354 9890886 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| TRDN | ASPH | 11069905 14525934 25348397 9287354 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| TRDN | CASQ2 | 10748065 11069905 11113462 14525934 14638677 25348397 27898060 7721813 9287354 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| TRDN | TMEM9B | 25348397 | N/A | physical interaction | ComPPI |
| TRDN | VTI1B | 25348397 | N/A | physical interaction | ComPPI |
| TRDN | GOSR2 | 25348397 | N/A | physical interaction | ComPPI |
| TRDN | BET1 | 25348397 | N/A | physical interaction | ComPPI |
| TRDN | GP1BB | 25348397 | N/A | physical interaction | ComPPI |
| STX8 | TRDN | 25348397 | N/A | physical interaction | ComPPI |
| NPM1 | TRDN | 24234451 30021884 | physical association | cross-linking study | IntAct |
| AIFM1 | TRDN | 24234451 30021884 | physical association | cross-linking study | IntAct |