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GENE：UBE2G1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2G1
FullNmae ubiquitin conjugating enzyme E2 G1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12482
EnsembleID ENSG00000132388
Uniprot P62253

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2G1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBE2G1 GO:0000209,GO:0004842,GO:0005515,GO:0005524,GO:0005829,GO:0006511,GO:0031625,GO:0043161,GO:0061631,GO:0061631,GO:0070062,GO:0070534,GO:0070936

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2G1 hsa:7326 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
UBE2G1 hsa:7326 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)
UBE2G1 hsa:7326 path:hsa05012 Parkinson disease - Homo sapiens (human)
UBE2G1 hsa:7326 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR UBE2G1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 UBE2G1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 UBE2G1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 UBE2G1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 UBE2G1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 UBE2G1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBE2G1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBE2G1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 UBE2G1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UBE2G1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBE2G1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 UBE2G1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UBE2G1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E UBE2G1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002971AB UBE2G1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD UBE2G1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000034E58D UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000338542 UBE2G1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB UBE2G1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 UBE2G1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A UBE2G1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF UBE2G1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 UBE2G1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 UBE2G1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 UBE2G1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 UBE2G1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F UBE2G1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CBL UBE2G1 11032556 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
UBE2G1 PRKN 11439185 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
UBE2G1 UBE2E1 14525934 25348397 8393731 N/A experimental interaction detection,in vitro ComPPI,HPRD
UBE2G1 RBCK1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2G1 AMFR 12847084 19560420 19661182 21209460 22101235 25348397 25451919 27898060 N/A physical interaction ComPPI,OmniPath
UBE2G1 ELAVL1 25348397 N/A physical interaction ComPPI
UBE2G1 HUWE1 25348397 N/A physical interaction ComPPI
UBE2G1 ITCH 25348397 N/A physical interaction ComPPI
UBE2G1 RBX1 25348397 N/A physical interaction ComPPI
UBE2G1 APP 25348397 N/A physical interaction ComPPI
UBE2G1 USP8 25348397 N/A physical interaction ComPPI
UBE2G1 WWP2 25348397 N/A physical interaction ComPPI
UBE2G1 UBA1 25348397 N/A physical interaction ComPPI
UBE2G1 MAP3K1 25348397 N/A physical interaction ComPPI
UBE2G1 CYP3A4 25348397 N/A physical interaction ComPPI
UBE2G1 CUL9 25348397 N/A physical interaction ComPPI
UBE2G1 FBXL2 25348397 N/A physical interaction ComPPI
UBE2G1 SMURF1 25348397 N/A physical interaction ComPPI
UBE2G1 TRIM25 25348397 N/A physical interaction ComPPI
UBE2G1 CUL1 22660580 24234451 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2G1 SDCBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE3A UBE2G1 10558980 14525934 N/A experimental interaction detection HPRD

Visualization










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