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GENE：UBE2O

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2O
FullNmae ubiquitin conjugating enzyme E2 O
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29554
EnsembleID ENSG00000175931
Uniprot Q9C0C9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2O immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBE2O GO:0003723,GO:0004842,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006513,GO:0016604,GO:0030513,GO:0042147,GO:0061630,GO:0061631,GO:0070534

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2O hsa:63893 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
UBE2O SMAD6 23455153 ubiquitination reaction,inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR UBE2O 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UBE2O 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 UBE2O 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 UBE2O 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 UBE2O 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 UBE2O 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D UBE2O 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE UBE2O 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000019907A UBE2O 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000017EA6A UBE2O 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005FDE70 UBE2O 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 UBE2O 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000105D19 UBE2O 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A UBE2O 24374217 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 UBE2O 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SYT11 UBE2O 25348397 N/A physical interaction ComPPI
RPS7 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
POP7 UBE2O 25348397 N/A physical interaction ComPPI
LCA5 UBE2O 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TRAF6 UBE2O 25348397 N/A physical interaction ComPPI
ZNF707 UBE2O 25348397 N/A physical interaction ComPPI
GSTP1 UBE2O 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GABARAPL2 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
NOL12 UBE2O 25348397 N/A physical interaction ComPPI
H2BC4 UBE2O 25348397 N/A physical interaction ComPPI
RAD21 UBE2O 25348397 N/A physical interaction ComPPI
FRG1 UBE2O 25348397 N/A physical interaction ComPPI
APPL1 UBE2O 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXNIP UBE2O 25348397 N/A physical interaction ComPPI
SMAD7 UBE2O 25348397 N/A physical interaction ComPPI
OSM UBE2O 25348397 N/A physical interaction ComPPI
JUN UBE2O 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PNKP UBE2O 25348397 N/A physical interaction ComPPI
CPNE1 UBE2O 12522145 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
CPNE2 UBE2O 12522145 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
CPNE4 UBE2O 12522145 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
BMP4 UBE2O 25348397 N/A physical interaction ComPPI
UBC UBE2O 25348397 N/A physical interaction ComPPI
UBA52 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
NTRK1 UBE2O 25348397 N/A physical interaction ComPPI
YBX1 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
ITGB3BP UBE2O 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
E4F1 UBE2O 25348397 N/A physical interaction ComPPI
SMARCA4 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TRAF3 UBE2O 25348397 N/A physical interaction ComPPI
MDK UBE2O 25348397 N/A physical interaction ComPPI
ECT2 UBE2O 25348397 N/A physical interaction ComPPI
GRK5 UBE2O 25348397 N/A physical interaction ComPPI
TRAF1 UBE2O 25348397 N/A physical interaction ComPPI
TRAF2 UBE2O 25348397 N/A physical interaction ComPPI
RLIM UBE2O 23455153 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RPL12 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TRAF5 UBE2O 25348397 N/A physical interaction ComPPI
ANKRD1 UBE2O 25348397 N/A physical interaction ComPPI
CHEK2 UBE2O 23178491 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TRAF4 UBE2O 25348397 N/A physical interaction ComPPI
PRKN UBE2O 25348397 N/A physical interaction ComPPI
TRIM25 UBE2O 25348397 N/A physical interaction ComPPI
CAVIN1 UBE2O 25348397 N/A physical interaction ComPPI
RIC8B UBE2O 25348397 N/A physical interaction ComPPI
TRIM27 UBE2O 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PAFAH1B3 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMAD6 UBE2O 23455153 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAP1 UBE2O 19615732 24234451 25348397 27705803 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
RPL29 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
RNF11 UBE2O 25348397 N/A physical interaction ComPPI
UBE2V1 UBE2O 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
HEXIM1 UBE2O 25348397 N/A physical interaction ComPPI
AURKAIP1 UBE2O 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HNRNPAB UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
CLK3 UBE2O 25348397 N/A physical interaction ComPPI
RPS20 UBE2O 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2O RNF10 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2O SIRT7 25348397 N/A physical interaction ComPPI
UBE2O WDR26 25348397 N/A physical interaction ComPPI
UBE2O ZNF687 25348397 N/A physical interaction ComPPI
UBE2O POLA2 25348397 N/A physical interaction ComPPI
UBE2O FTSJ3 25348397 N/A physical interaction ComPPI
UBE2O NXF1 25348397 N/A physical interaction ComPPI
UBE2O BUD23 25348397 N/A physical interaction ComPPI
UBE2O LUC7L 25348397 N/A physical interaction ComPPI
UBE2O SFRP4 25348397 N/A physical interaction ComPPI
UBE2O LUC7L2 25348397 N/A physical interaction ComPPI
UBE2O NAP1L1 25348397 N/A physical interaction ComPPI
UBE2O H2BC1 25348397 N/A physical interaction ComPPI
UBE2O ZFP41 25348397 N/A physical interaction ComPPI
UBE2O KIAA0753 25348397 N/A physical interaction ComPPI
UBE2O H2BC11 25348397 N/A physical interaction ComPPI
UBE2O MED4 25348397 N/A physical interaction ComPPI
UBE2O NEPRO 25348397 N/A physical interaction ComPPI
UBE2O JPH4 25348397 N/A physical interaction ComPPI
UBE2O FGFRL1 25348397 N/A physical interaction ComPPI
UBE2O PLD1 25348397 N/A physical interaction ComPPI
UBE2O PLEKHG4 25348397 N/A physical interaction ComPPI
UBE2O RPL18 25348397 N/A physical interaction ComPPI
UBE2O AKT2 25348397 N/A physical interaction ComPPI
UBE2O AKAP17A 25348397 N/A physical interaction ComPPI
UBE2O MYO5A 25348397 N/A physical interaction ComPPI
UBE2O LLGL2 25348397 N/A physical interaction ComPPI
UBE2O ZNF556 25348397 N/A physical interaction ComPPI
UBE2O ZNF92 25348397 N/A physical interaction ComPPI
UBE2O MRPL35 25348397 N/A physical interaction ComPPI
UBE2O IFRD2 25348397 N/A physical interaction ComPPI
UBE2O RPL15 25348397 N/A physical interaction ComPPI
UBE2O ZNF563 25348397 N/A physical interaction ComPPI
UBE2O L3MBTL2 25348397 N/A physical interaction ComPPI
UBE2O ZNF517 25348397 N/A physical interaction ComPPI
UBE2O ZNF574 25348397 N/A physical interaction ComPPI
UBE2O ZNF669 25348397 N/A physical interaction ComPPI
UBE2O EPB41L5 25348397 N/A physical interaction ComPPI
UBE2O CCDC33 25348397 N/A physical interaction ComPPI
UBE2O TRIM11 25348397 N/A physical interaction ComPPI
UBE2O MCAM 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2O XAGE1A 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2O CHD1L 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2O SAP30L 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2O SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UBE2O CBX6 21282530 24234451 25348397 association tandem affinity purification ComPPI,IntAct
UBE2O SFMBT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2O KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
UBE2O FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IKZF5 UBE2O 25348397 N/A physical interaction ComPPI
LZTR1 UBE2O 25348397 N/A physical interaction ComPPI
SHBG UBE2O 14525934 15862967 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
UBE2O UBE2O 23455153 24234451 physical association anti tag coimmunoprecipitation IntAct
COX4I1 UBE2O 24234451 30021884 physical association cross-linking study IntAct
ERP29 UBE2O 24234451 30021884 physical association cross-linking study IntAct
UBE2O SMAD6 23455153 27898060 inhibition N/A OmniPath

Visualization










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