Gene Information gene info

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GENE：CHEK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CHEK1
FullNmae checkpoint kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1925
EnsembleID ENSG00000149554
Uniprot O14757

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CHEK1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CHEK1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CHEK1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CHEK1 GO:0000077,GO:0000077,GO:0000086,GO:0000781,GO:0000785,GO:0000794,GO:0001833,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005615,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005657,GO:0005737,GO:0005813,GO:0005829,GO:0006260,GO:0006281,GO:0006338,GO:0006468,GO:0006468,GO:0006915,GO:0006974,GO:0006974,GO:0006997,GO:0007095,GO:0010569,GO:0018107,GO:0019904,GO:0032991,GO:0035402,GO:0035556,GO:0042127,GO:0042770,GO:0043231,GO:0044818,GO:0045787,GO:0045814,GO:0045839,GO:0046602,GO:0070317,GO:0071260,GO:0071313,GO:0090399,GO:0106310,GO:1901796,GO:1902742,GO:2000279

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CHEK1 hsa:1111 path:hsa04110 Cell cycle - Homo sapiens (human)
CHEK1 hsa:1111 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
CHEK1 hsa:1111 path:hsa04218 Cellular senescence - Homo sapiens (human)
CHEK1 hsa:1111 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
CHEK1 hsa:1111 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
CHEK1 hsa:1111 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATRIP CHEK1 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
ATR CHEK1 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
CLSPN CHEK1 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
PCNA CHEK1 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
CHEK1 TIPIN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983 26192618 interaction type N/A ACSN
ATM CHEK1 10608806 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23180781 23847781 26192618 9168117 9858600 interaction type,phosphorylation reaction in-gel kinase assay ACSN,InnateDB
BRCA1 CHEK1 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 26192618 9346961 9892649 interaction type N/A ACSN
RAD17 CHEK1 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
TOPBP1 CHEK1 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611 26192618 interaction type N/A ACSN
CHEK1 CDC25A 15459660 15798197 17102137 17116885 17296725 17384638 17568790 17582221 18677104 19793801 20126263 26192618 interaction type N/A ACSN
CHEK1 FANCI 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801 26192618 interaction type N/A ACSN
CHEK1 FANCA 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801 26192618 interaction type N/A ACSN
CHEK1 FANCD2 14988723 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801 26192618 interaction type N/A ACSN
CHEK1 FANCE 15459660 15798197 17102137 17116885 17296725 17296736 17384638 17582221 18677104 18931676 19686080 19793801 26192618 interaction type N/A ACSN
CHEK1 FANCG 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801 26192618 interaction type N/A ACSN
CHEK1 ORC1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 ORC2 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 ORC3 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 ORC4 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 ORC5 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 ORC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 MCM2 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 MCM3 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 MCM4 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 MCM5 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 MCM6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 MCM7 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 CDT1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 CDC6 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 CDC45 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 RPA1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 RPA2 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 RPA3 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
HUS1 CHEK1 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD1 CHEK1 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
E2F1 CHEK1 10884389 12496474 15220350 15279786 17218262 17303408 17660363 18590585 18660752 19525936 20376879 26192618 7575488 interaction type N/A ACSN
CHEK1 WEE1 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 19793801 23508805 23897299 26192618 interaction type N/A ACSN
CHEK1 XIAP 14759516 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
BIRC2 CHEK1 14759516 23180781 physical association gst pull down InnateDB
TP53 CHEK1 16990795 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
YWHAG CHEK1 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
E2F4 CHEK1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CHEK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA CHEK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CHEK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CHEK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CHEK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BCL6 CHEK1 18346918 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CHEK1 18660752 trascriptional regulation,stimulation inferred by curator TFlink
MYC CHEK1 23269272 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CHEK1 11152453 15016801 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F0F49 CHEK1 19956200 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000F6E49 CHEK1 19956200 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000F6E49 CHEK1 19956200 23313552 25416803 26867682 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00000F0F49 CHEK1 19956200 22469983 23313552 25416803 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS00000AA464 CHEK1 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00001C308D CHEK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C CHEK1 22473208 23313552 23622248 25416803 25594541 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,clash,miRNA interference luciferase reporter assay TarBase
URS000007D64A CHEK1 23313552 24464213 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000006FDD4 CHEK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 CHEK1 22473208 23313552 25416803 25594541 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000040EE1D CHEK1 22473208 23313552 25416803 25840419 26867682 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00000C5969 CHEK1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 CHEK1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 CHEK1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 CHEK1 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004719AB CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 CHEK1 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002E0524 CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018E72A CHEK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 CHEK1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB CHEK1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C CHEK1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A CHEK1 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHEK1 CTR9 22135298 phosphorylation N/A PhosphoSite
CHEK1 LAMC1 22135298 phosphorylation N/A PhosphoSite
CHEK1 DDX19A 22135298 phosphorylation N/A PhosphoSite
CHEK1 HNRNPA2B1 22135298 phosphorylation N/A PhosphoSite
CHEK1 RPL19 22135298 phosphorylation N/A PhosphoSite
CHEK1 YBX1 22135298 phosphorylation N/A PhosphoSite
CHEK1 TICRR 22135298 phosphorylation N/A PhosphoSite
CHEK1 BAZ1A 22135298 phosphorylation N/A PhosphoSite
CHEK1 BLM 22135298 phosphorylation N/A PhosphoSite
CHEK1 E2F3 22135298 phosphorylation N/A PhosphoSite
CHEK1 CHEK1 22135298 phosphorylation N/A PhosphoSite
CHEK1 TRIP12 22135298 phosphorylation N/A PhosphoSite
CHEK1 TLK1 22135298 phosphorylation N/A PhosphoSite
CHEK1 CLK3 22135298 phosphorylation N/A PhosphoSite
CHEK1 EPRS1 22135298 phosphorylation N/A PhosphoSite
CHEK1 SETMAR 22135298 phosphorylation N/A PhosphoSite
CHEK1 PRR5 22135298 phosphorylation N/A PhosphoSite
CHEK1 E2F6 22135298 phosphorylation N/A PhosphoSite
CHEK1 TP53 22135298 phosphorylation N/A PhosphoSite
CHEK1 TP73 22135298 phosphorylation N/A PhosphoSite
CHEK1 GTF3C1 22135298 phosphorylation N/A PhosphoSite
CHEK1 RBM26 22135298 phosphorylation N/A PhosphoSite
CHEK1 YBX3 22135298 phosphorylation N/A PhosphoSite
CHEK1 INF2 22135298 phosphorylation N/A PhosphoSite
CHEK1 CDC25A 22135298 phosphorylation N/A PhosphoSite
CHEK1 MKI67 22135298 phosphorylation N/A PhosphoSite
CHEK1 TFDP1 22135298 phosphorylation N/A PhosphoSite
CHEK1 ERRFI1 22135298 phosphorylation N/A PhosphoSite
CHEK1 FANCD2 22135298 phosphorylation N/A PhosphoSite
CHEK1 RALY 22135298 phosphorylation N/A PhosphoSite
CHEK1 TP53BP1 22135298 phosphorylation N/A PhosphoSite
CHEK1 ZNF638 22135298 phosphorylation N/A PhosphoSite
CHEK1 SCAF11 22135298 phosphorylation N/A PhosphoSite
CHEK1 SRRM2 22135298 phosphorylation N/A PhosphoSite
CHEK1 CHD7 22135298 phosphorylation N/A PhosphoSite
CHEK1 GOLGA4 22135298 phosphorylation N/A PhosphoSite
CHEK1 ADD3 22135298 phosphorylation N/A PhosphoSite
CHEK1 KIFC1 22135298 phosphorylation N/A PhosphoSite
CHEK1 SEPTIN7 22135298 phosphorylation N/A PhosphoSite
CHEK1 MATR3 22135298 phosphorylation N/A PhosphoSite
CHEK1 MCM5 22135298 phosphorylation N/A PhosphoSite
CHEK1 SPEN 22135298 phosphorylation N/A PhosphoSite
CHEK1 LATS2 22135298 phosphorylation N/A PhosphoSite
CHEK1 RIF1 22135298 phosphorylation N/A PhosphoSite
CHEK1 AURKB 22135298 phosphorylation N/A PhosphoSite
CHEK1 CWC25 22135298 phosphorylation N/A PhosphoSite
CHEK1 RBM14 22135298 phosphorylation N/A PhosphoSite
CHEK1 IDI1 22135298 phosphorylation N/A PhosphoSite
CHEK1 CAAP1 22135298 phosphorylation N/A PhosphoSite
CHEK1 PRRC2C 22135298 phosphorylation N/A PhosphoSite
CHEK1 PHF2 22135298 phosphorylation N/A PhosphoSite
CHEK1 SNCB 22135298 phosphorylation N/A PhosphoSite
CHEK1 HNRNPM 22135298 phosphorylation N/A PhosphoSite
CHEK1 MED1 22135298 phosphorylation N/A PhosphoSite
CHEK1 CCDC6 22135298 phosphorylation N/A PhosphoSite
CHEK1 YBX2 22135298 phosphorylation N/A PhosphoSite
CHEK1 WIZ 22135298 phosphorylation N/A PhosphoSite
CHEK1 ZC3HC1 22135298 phosphorylation N/A PhosphoSite
CHEK1 NUP153 22135298 phosphorylation N/A PhosphoSite
CHEK1 SLTM 22135298 phosphorylation N/A PhosphoSite
CHEK1 OGT 22135298 phosphorylation N/A PhosphoSite
CHEK1 NEK11 22135298 phosphorylation N/A PhosphoSite
CHEK1 SSBP1 22135298 phosphorylation N/A PhosphoSite
CHEK1 MDC1 22135298 phosphorylation N/A PhosphoSite
CHEK1 KPNA2 22135298 phosphorylation N/A PhosphoSite
CHEK1 MCM3 22135298 phosphorylation N/A PhosphoSite
CHEK1 POP4 22135298 phosphorylation N/A PhosphoSite
CHEK1 ADD2 22135298 phosphorylation N/A PhosphoSite
CHEK1 ADD1 22135298 phosphorylation N/A PhosphoSite
CHEK1 ZNF395 22135298 phosphorylation N/A PhosphoSite
CHEK1 XRCC6 22135298 phosphorylation N/A PhosphoSite
CHEK1 MAD2L1 22135298 phosphorylation N/A PhosphoSite
CHEK1 STK4 22135298 phosphorylation N/A PhosphoSite
CHEK1 MYCBP2 22135298 phosphorylation N/A PhosphoSite
CHEK1 BUD13 22135298 phosphorylation N/A PhosphoSite
CHEK1 TBC1D4 22135298 phosphorylation N/A PhosphoSite
CHEK1 MAP2K2 22135298 phosphorylation N/A PhosphoSite
CHEK1 DDX24 22135298 phosphorylation N/A PhosphoSite
CHEK1 CTTN 22135298 phosphorylation N/A PhosphoSite
CHEK1 RBM42 22135298 phosphorylation N/A PhosphoSite
CHEK1 FEN1 22135298 phosphorylation N/A PhosphoSite
CHEK1 EBNA1BP2 22135298 phosphorylation N/A PhosphoSite
CHEK1 TRIM28 22135298 phosphorylation N/A PhosphoSite
CHEK1 RANBP2 22135298 phosphorylation N/A PhosphoSite
CHEK1 MYBBP1A 22135298 phosphorylation N/A PhosphoSite
CHEK1 SENP2 22135298 phosphorylation N/A PhosphoSite
CHEK1 CAMSAP2 22135298 phosphorylation N/A PhosphoSite
CHEK1 CHTOP 22135298 phosphorylation N/A PhosphoSite
CHEK1 CDC25B 22135298 phosphorylation N/A PhosphoSite
CHEK1 PRRC2B 22135298 phosphorylation N/A PhosphoSite
CHEK1 LMNA 22135298 phosphorylation N/A PhosphoSite
CHEK1 H3C1 22135298 phosphorylation N/A PhosphoSite
CHEK1 MDM4 22135298 phosphorylation N/A PhosphoSite
CHEK1 ZBTB11 22135298 phosphorylation N/A PhosphoSite
CHEK1 PHF8 22135298 phosphorylation N/A PhosphoSite
CHEK1 RACGAP1 22135298 phosphorylation N/A PhosphoSite
CHEK1 DDX19B 22135298 phosphorylation N/A PhosphoSite
CHEK1 TLK2 22135298 phosphorylation N/A PhosphoSite
CHEK1 ARHGEF2 22135298 phosphorylation N/A PhosphoSite
CHEK1 PPME1 22135298 phosphorylation N/A PhosphoSite
CHEK1 H3-3A 22135298 phosphorylation N/A PhosphoSite
CHEK1 MAP4 22135298 phosphorylation N/A PhosphoSite
CHEK1 PRPF3 22135298 phosphorylation N/A PhosphoSite
CHEK1 HDLBP 22135298 phosphorylation N/A PhosphoSite
CHEK1 PROSER2 22135298 phosphorylation N/A PhosphoSite
CHEK1 CDK13 22135298 phosphorylation N/A PhosphoSite
CHEK1 NHS 22135298 phosphorylation N/A PhosphoSite
CHEK1 RRP12 22135298 phosphorylation N/A PhosphoSite
CHEK1 CLSPN 22135298 phosphorylation N/A PhosphoSite
CHEK1 PPP2R5D 22135298 phosphorylation N/A PhosphoSite
CHEK1 DRG2 22135298 phosphorylation N/A PhosphoSite
CHEK1 PLRG1 22135298 phosphorylation N/A PhosphoSite
CHEK1 HIVEP1 22135298 phosphorylation N/A PhosphoSite
CHEK1 NCBP3 22135298 phosphorylation N/A PhosphoSite
CHEK1 FANCE 22135298 phosphorylation N/A PhosphoSite
CHEK1 FYTTD1 22135298 phosphorylation N/A PhosphoSite
CHEK1 CDK1 22135298 phosphorylation N/A PhosphoSite
CHEK1 POLDIP3 22135298 phosphorylation N/A PhosphoSite
CHEK1 RPL13 22135298 phosphorylation N/A PhosphoSite
CHEK1 LIG1 22135298 phosphorylation N/A PhosphoSite
CHEK1 CSNK2B 22135298 phosphorylation N/A PhosphoSite
CHEK1 SYK 22135298 phosphorylation N/A PhosphoSite
CHEK1 KPNA1 22135298 phosphorylation N/A PhosphoSite
CHEK1 MINK1 22135298 phosphorylation N/A PhosphoSite
CHEK1 CDC25C 22135298 phosphorylation N/A PhosphoSite
CHEK1 MAP2K1 22135298 phosphorylation N/A PhosphoSite
CHEK1 RB1 22135298 phosphorylation N/A PhosphoSite
CHEK1 NFKB1 22135298 phosphorylation N/A PhosphoSite
CHEK1 OSBPL11 22135298 phosphorylation N/A PhosphoSite
CHEK1 UIMC1 22135298 phosphorylation N/A PhosphoSite
CHEK1 SIN3A 22135298 phosphorylation N/A PhosphoSite
CHEK1 TNK1 22135298 phosphorylation N/A PhosphoSite
CHEK1 EML3 22135298 phosphorylation N/A PhosphoSite
CHEK1 CEP170B 22135298 phosphorylation N/A PhosphoSite
CHEK1 LMO7 22135298 phosphorylation N/A PhosphoSite
CDK1 CHEK1 22135298 phosphorylation N/A PhosphoSite
CDK2 CHEK1 22135298 phosphorylation N/A PhosphoSite
RPS6KA1 CHEK1 22135298 phosphorylation N/A PhosphoSite
ATR CHEK1 22135298 phosphorylation N/A PhosphoSite
MAP3K8 CHEK1 22135298 phosphorylation N/A PhosphoSite
ATM CHEK1 22135298 phosphorylation N/A PhosphoSite
AKT1 CHEK1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SNW1 CHEK1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L CHEK1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PCNA CHEK1 25348397 N/A physical interaction ComPPI
CDKN1A CHEK1 25348397 N/A physical interaction ComPPI
TP53BP1 CHEK1 25348397 N/A physical interaction ComPPI
VCP CHEK1 25348397 N/A physical interaction ComPPI
YWHAG CHEK1 14525934 15324660 20639859 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,pull down,in vivo ComPPI,HPRD,IntAct
XIAP CHEK1 14525934 14759516 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SMAD4 CHEK1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HSP90AB1 CHEK1 16330544 17145710 18820127 22939624 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,pull down,luminescence based mammalian interactome mapping ComPPI,IntAct,OmniPath
BCL2L1 CHEK1 25348397 N/A physical interaction ComPPI
LDLRAP1 CHEK1 25348397 N/A physical interaction ComPPI
CBY1 CHEK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ERRFI1 CHEK1 22505024 24234451 25348397 phosphorylation reaction enzymatic study ComPPI,IntAct
VAV1 CHEK1 25348397 N/A physical interaction ComPPI
MAPK1 CHEK1 25348397 N/A physical interaction ComPPI
RACGAP1 CHEK1 25348397 N/A physical interaction ComPPI
NFATC1 CHEK1 25348397 N/A physical interaction ComPPI
ATR CHEK1 11252893 11390642 14525934 17686975 24234451 25348397 N/A experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
PRKDC CHEK1 25348397 N/A physical interaction ComPPI
PPP1R15A CHEK1 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
JUN CHEK1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RB1 CHEK1 17380128 24234451 25348397 phosphorylation reaction pull down,physical interaction,protein kinase assay ComPPI,IntAct
COPS5 CHEK1 25348397 N/A physical interaction ComPPI
USP7 CHEK1 25348397 N/A physical interaction ComPPI
POLA1 CHEK1 25348397 N/A physical interaction ComPPI
GIGYF1 CHEK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
YWHAB CHEK1 20639859 24234451 25348397 physical association pull down ComPPI,IntAct
YWHAZ CHEK1 20639859 24234451 25348397 physical association pull down ComPPI,IntAct
PPM1A CHEK1 25348397 N/A physical interaction ComPPI
HSP90AA1 CHEK1 14525934 16330544 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
XRCC5 CHEK1 25348397 N/A physical interaction ComPPI
MSH6 CHEK1 25348397 N/A physical interaction ComPPI
CSNK2A1 CHEK1 25348397 N/A physical interaction ComPPI
XRCC6 CHEK1 12756247 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NEK2 CHEK1 25348397 N/A physical interaction ComPPI
NFATC2 CHEK1 25348397 N/A physical interaction ComPPI
SQSTM1 CHEK1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RELA CHEK1 14525934 15775976 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PKM CHEK1 25348397 N/A protein kinase assay ComPPI
RAD51 CHEK1 14525934 15665856 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
FANCD2 CHEK1 25348397 N/A physical interaction ComPPI
BLM CHEK1 14525934 15364958 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ATM CHEK1 11252893 11390642 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
XPO1 CHEK1 25348397 N/A physical interaction ComPPI
RPA2 CHEK1 20639859 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
MDM4 CHEK1 14525934 16163388 16511572 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,protein kinase assay,in vitro ComPPI,HPRD,IntAct
AATF CHEK1 14525934 17157788 24234451 25348397 phosphorylation reaction experimental interaction detection,protein kinase assay,in vitro ComPPI,HPRD,IntAct
RAD23A CHEK1 25348397 N/A physical interaction ComPPI
UBA2 CHEK1 25348397 N/A physical interaction ComPPI
SRSF2 CHEK1 22863007 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
CHEK1 CUL1 14525934 16137618 17290223 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CHEK1 CUL4A 14525934 16137618 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CHEK1 CLSPN 12766152 14525934 16123041 16963448 24234451 25348397 phosphorylation reaction,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
CHEK1 TLK1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
CHEK1 CDC25A 12399544 12676583 14525934 17292828 24234451 25348397 phosphorylation reaction affinity chromatography technology,experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
CHEK1 CDC25B 25348397 N/A affinity chromatography technology,physical interaction,physical interaction,in vitro ComPPI
CHEK1 CSNK2B 12902976 14525934 15225637 24234451 25348397 phosphorylation reaction experimental interaction detection,in vitro,in vivo ComPPI,HPRD,IntAct
CHEK1 TIMELESS 14525934 15798197 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CHEK1 CHUK 14525934 17962807 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CHEK1 CDC25C 10557092 10681541 11333986 11551930 11836499 14525934 16330544 24234451 25348397 9278511 9278512 phosphorylation reaction affinity chromatography technology,experimental interaction detection,physical interaction,protein kinase assay,in vitro ComPPI,HPRD,IntAct
CHEK1 AKT1 12062056 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CHEK1 MSH2 25348397 N/A physical interaction ComPPI
CHEK1 SFN 25348397 N/A physical interaction ComPPI
CHEK1 TP53 10673501 11551930 11709713 11896572 14525934 16511572 24234451 25348397 9765199 phosphorylation reaction experimental interaction detection,physical interaction,protein kinase assay ComPPI,HPRD,IntAct
CHEK1 NEK9 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHEK1 MCPH1 25348397 N/A physical interaction ComPPI
CHEK1 DNMT1 25348397 N/A physical interaction ComPPI
CHEK1 DDB1 25348397 N/A physical interaction ComPPI
CHEK1 FANCE 25348397 N/A physical interaction ComPPI
CHEK1 MEN1 20969866 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
CHEK1 HSP90AA2P 25348397 N/A physical interaction ComPPI
CHEK1 LATS2 25348397 N/A physical interaction ComPPI
CHEK1 MEPE 25348397 N/A physical interaction ComPPI
CHEK1 BRCA1 11836499 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
CHEK1 FEM1B 25348397 N/A physical interaction ComPPI
CHEK1 APP 25348397 N/A physical interaction ComPPI
CHEK1 MED15 25348397 N/A physical interaction ComPPI
CHEK1 DTL 23109433 23533280 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CHEK1 TOPBP1 25348397 N/A physical interaction ComPPI
CHEK1 BTG3 25348397 N/A physical interaction ComPPI
CHEK1 PIGM 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CHEK1 HECW2 25348397 N/A physical interaction ComPPI
CHEK1 TNRC6B 25348397 N/A physical interaction ComPPI
CHEK1 SETMAR 25348397 N/A physical interaction ComPPI
CHEK1 ZEB1 25348397 N/A physical interaction ComPPI
CHEK1 FUS 24234451 25348397 25852190 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHEK1 SNX11 25348397 N/A physical interaction ComPPI
CHEK1 HLA-DRB5 25348397 N/A physical interaction ComPPI
CHEK1 BCL2L14 25348397 N/A physical interaction ComPPI
CHEK1 L3HYPDH 25348397 N/A physical interaction ComPPI
CHEK1 TCEAL1 25348397 N/A physical interaction ComPPI
CHEK1 CHRNA9 25348397 N/A physical interaction ComPPI
CHEK1 HNRNPD 25348397 N/A physical interaction ComPPI
CHEK1 PTBP1 25348397 N/A physical interaction ComPPI
CHEK1 PTBP3 25348397 N/A physical interaction ComPPI
CHEK1 TARS1 25348397 N/A physical interaction ComPPI
CHEK1 CDK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHEK1 UBA1 25348397 N/A physical interaction ComPPI
CHEK1 UBE2T 25348397 N/A physical interaction ComPPI
CHEK1 NAT9 25348397 N/A physical interaction ComPPI
CHEK1 ERCC6L 25348397 N/A physical interaction ComPPI
CHEK1 IL13RA2 25348397 N/A physical interaction ComPPI
CHEK1 DNAAF11 25348397 N/A physical interaction ComPPI
CHEK1 PLA2G10 25348397 N/A physical interaction ComPPI
CHEK1 CTSE 25348397 N/A physical interaction ComPPI
CHEK1 UNC5CL 25348397 N/A physical interaction ComPPI
CHEK1 NELL1 25348397 N/A physical interaction ComPPI
CHEK1 KCTD3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 KIF13B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 ZBTB21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 LRFN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 DENND1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 SH3PXD2A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 SRGAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 EIF4E2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHEK1 ILKAP 25348397 N/A physical interaction ComPPI
CHEK1 ATXN3 25348397 N/A physical interaction ComPPI
CHEK1 FBXO6 25348397 N/A physical interaction ComPPI
CHEK1 SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CHEK1 ATRIP 20639859 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
CHEK1 KAT5 22863007 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
CHEK1 CEP164 22863007 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
CHEK1 SMURF1 24234451 25249323 25348397 27898060 physical association anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
CHEK1 UBB 14525934 16137618 N/A experimental interaction detection HPRD
CHEK1 CDC25A 11298456 12399544 12676583 12759351 12963847 14559997 14681206 14752276 16647857 17292828 18480045 20068082 27898060 9278511 inhibition,stimulant N/A OmniPath
CHEK1 AURKB 17276342 27898060 stimulant N/A OmniPath
CHEK1 RAD51 15665856 18285803 27898060 stimulant N/A OmniPath
CHEK1 RB1 17380128 27898060 stimulant N/A OmniPath
CHEK1 CDC25B 16314342 17003105 27898060 9278511 inhibition,stimulant N/A OmniPath
CHEK1 NEK11 19734889 20090422 27898060 stimulant N/A OmniPath
CHEK1 FANCE 17296736 27898060 stimulant N/A OmniPath
CDK2 CHEK1 21765472 21907702 27898060 stimulant N/A OmniPath
ATR CHEK1 10608806 10859163 10859164 11090622 11252893 11390642 12446774 12588868 12660173 12676583 12676925 12676962 12766152 12781359 14657349 14681223 14988723 15096610 15190204 15272308 15279789 15485915 15533933 15650047 15665856 15707391 15775976 15870257 16137618 16293623 16360315 16431910 16963448 17124492 17327276 17525332 17686975 18272544 18353973 18449195 18669648 18691976 19091954 19330022 19351595 19716789 20116089 20160490 20501833 21532626 21566061 21777809 21965652 22037398 22424773 22863316 23318425 23454898 23954429 24253929 24421316 24632611 24902048 25043304 25218637 25690891 25733714 25893301 25965828 26082189 26165835 26166705 26572825 27898060 stimulant N/A OmniPath
CHEK1 NFKB1 22152481 23180782 27898060 inhibition N/A OmniPath
ATM CHEK1 10608806 10859164 11252893 11390642 12446774 12588868 12660173 12676583 12676925 12676962 14657349 14681223 14988723 15533933 15650047 15707391 15870257 17525332 18691976 19716789 20068082 27898060 stimulant N/A OmniPath
AKT1 CHEK1 12062056 15107605 17418864 18669648 18691976 19664995 20068231 27898060 inhibition,stimulant N/A OmniPath
CHEK1 WEE1 15070733 19500427 20068082 27898060 7681363 8515817 inhibition,stimulant N/A OmniPath
CHEK1 H3C1 12560483 18066052 18243098 18451105 20068082 20948546 21357687 23844048 27898060 inhibition N/A OmniPath
CHEK1 CDC25C 10557092 10681541 11016625 11333986 11390642 11551930 11836499 12660173 15150265 15629715 15705874 16330544 16705183 17035231 19330022 20068082 20068231 27898060 9278511 9278512 9543386 inhibition N/A OmniPath
CHEK1 FANCA 11855836 27898060 stimulant N/A OmniPath
CHEK1 TP53 10673501 11551930 11709713 11896572 12756247 12781359 12897801 15364958 15659650 16511572 16990795 17339337 18319725 27898060 9765199 stimulant N/A OmniPath
TP53 CHEK1 10673501 11551930 11709713 11896572 12756247 15364958 16511572 16990795 27898060 9765199 N/A N/A OmniPath
PPM1D CHEK1 15870257 27898060 inhibition N/A OmniPath
CHEK1 FANCD2 19861535 27898060 stimulant N/A OmniPath
E2F1 CHEK1 18660752 27898060 inhibition,stimulant N/A OmniPath
CHEK1 ING1 17585055 18388957 27898060 N/A N/A OmniPath
CHEK1 E2F3 19917728 27898060 stimulant N/A OmniPath
CDK1 CHEK1 12062056 15674326 16629900 21765472 27898060 stimulant N/A OmniPath
CHEK1 UBE2B 19158510 20068082 27898060 stimulant N/A OmniPath
CHEK1 BLM 15364958 20719863 27898060 stimulant N/A OmniPath
CDK5RAP3 CHEK1 19223857 27898060 inhibition N/A OmniPath
CHEK1 FANCL 19861535 27898060 stimulant N/A OmniPath
BIRC2 CHEK1 14759516 27898060 N/A N/A OmniPath
CHEK1 TLK1 12660173 12955071 18669648 20068082 20068231 27898060 inhibition,stimulant N/A OmniPath
CHEK1 RELA 15775976 27898060 N/A N/A OmniPath
CSNK2A1 CHEK1 12902976 15225637 15975956 27898060 N/A N/A OmniPath
PPP2CA CHEK1 17015476 27898060 inhibition N/A OmniPath
CHEK1 MCM4 12714602 27898060 N/A N/A OmniPath
CHEK1 MATR3 20962082 27898060 N/A N/A OmniPath
CHEK1 TP73 14585975 27898060 stimulant N/A OmniPath
CHEK1 CSNK2B 12902976 15225637 27898060 N/A N/A OmniPath
CSNK2B CHEK1 12902976 15225637 27898060 stimulant N/A OmniPath
CHEK1 CLSPN 11090622 12766152 15279790 15371427 16123041 16963448 18451105 23109433 27898060 stimulant N/A OmniPath
CLSPN CHEK1 11090622 12766152 15279790 15371427 16123041 16963448 18451105 23109433 27898060 inhibition,stimulant N/A OmniPath
CHEK1 MAD2L1 21041666 27898060 N/A N/A OmniPath
CHEK1 RASSF1 24197116 27898060 N/A N/A OmniPath
CHEK1 BRCA2 18317453 27898060 stimulant N/A OmniPath
CHEK1 MCM3 18283219 27898060 N/A N/A OmniPath
CHEK1 MDM4 16163388 16511572 18356162 27898060 inhibition N/A OmniPath
CHEK1 PTTG1 16647857 27898060 stimulant N/A OmniPath
CHEK1 CDC7 20068082 27898060 stimulant N/A OmniPath
CHEK1 SNCB 21699177 27898060 N/A N/A OmniPath
CHEK1 H3-3A 18243098 27898060 stimulant N/A OmniPath
CHEK1 SYK 22585575 27898060 inhibition N/A OmniPath
CHEK1 ERRFI1 22505024 27898060 N/A N/A OmniPath
PPP2CB CHEK1 17015476 27898060 inhibition N/A OmniPath
CHEK1 KIFC1 24510915 27898060 N/A N/A OmniPath
CHEK1 TICRR 25557548 27898060 N/A N/A OmniPath
CHEK1 SETMAR 22231448 25024738 27898060 N/A N/A OmniPath

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