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GENE：UXS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UXS1
FullNmae UDP-glucuronate decarboxylase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17729
EnsembleID ENSG00000115652
Uniprot Q8NBZ7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UXS1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UXS1 GO:0005737,GO:0032580,GO:0033320,GO:0033320,GO:0042732,GO:0042802,GO:0042803,GO:0048040,GO:0048040,GO:0070062,GO:0070403,GO:0070403,GO:1902494

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UXS1 hsa:80146 path:hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human)
UXS1 hsa:80146 path:hsa01100 Metabolic pathways - Homo sapiens (human)
UXS1 hsa:80146 path:hsa01250 Biosynthesis of nucleotide sugars - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR UXS1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UXS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UXS1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 UXS1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 UXS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 UXS1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000600E6 UXS1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F UXS1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 UXS1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 UXS1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 UXS1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA UXS1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DPEP1 UXS1 25348397 N/A physical interaction ComPPI
MAPK3 UXS1 25348397 N/A physical interaction ComPPI
NUP85 UXS1 25348397 N/A physical interaction ComPPI
PEX19 UXS1 25348397 N/A physical interaction ComPPI
HNRNPL UXS1 25348397 N/A physical interaction ComPPI
NUP98 UXS1 25348397 N/A physical interaction ComPPI
IPO7 UXS1 25348397 N/A physical interaction ComPPI
ATP2B2 UXS1 25348397 N/A physical interaction ComPPI
MT-CO1 UXS1 25348397 N/A physical interaction ComPPI
XPO4 UXS1 25348397 N/A physical interaction ComPPI
ANK3 UXS1 25348397 N/A physical interaction ComPPI
DDX1 UXS1 25348397 N/A physical interaction ComPPI
HLA-B UXS1 25348397 N/A physical interaction ComPPI
EIF2B5 UXS1 25348397 N/A physical interaction ComPPI
AKT1 UXS1 11877387 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
NUP107 UXS1 25348397 N/A physical interaction ComPPI
NUP160 UXS1 25348397 N/A physical interaction ComPPI
TSKU UXS1 25348397 N/A physical interaction ComPPI
UXS1 FAM98A 25348397 N/A physical interaction ComPPI
UXS1 EIF2B3 25348397 N/A physical interaction ComPPI
UXS1 TPCN2 25348397 N/A physical interaction ComPPI
UXS1 GEMIN4 25348397 N/A physical interaction ComPPI
HSPD1 UXS1 24234451 30021884 physical association cross-linking study IntAct

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