GENE：WDR89
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | WDR89 |
| FullNmae | WD repeat domain 89 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20489 |
| EnsembleID | ENSG00000140006 |
| Uniprot | Q96FK6 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| WDR89 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| WDR89 | GO:0021591,GO:0022038 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | WDR89 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | WDR89 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | WDR89 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | WDR89 | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| FOXA1 | WDR89 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | WDR89 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | WDR89 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | WDR89 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | WDR89 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | WDR89 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | WDR89 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | WDR89 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | WDR89 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | WDR89 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002152A8 | WDR89 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS0000042E1F | WDR89 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | WDR89 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | WDR89 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | WDR89 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | WDR89 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | WDR89 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BYSL | WDR89 | 25348397 | N/A | physical interaction | ComPPI |
| RPL10A | WDR89 | 25348397 | N/A | physical interaction | ComPPI |
| SIGLEC7 | WDR89 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | WDR89 | 25348397 | N/A | physical interaction | ComPPI |
| SOCS6 | WDR89 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PHYHIP | WDR89 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| POLR3F | WDR89 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| WDR89 | APP | 25348397 | N/A | physical interaction | ComPPI |