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GENE：ZC3HC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZC3HC1
FullNmae zinc finger C3HC-type containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29913
EnsembleID ENSG00000091732
Uniprot Q86WB0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZC3HC1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ZC3HC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ZC3HC1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ZC3HC1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ZC3HC1 GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0007049,GO:0008270,GO:0016567,GO:0019901,GO:0031965,GO:0051301,GO:2001240

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ZC3HC1 SKP1 16009132 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
ZC3HC1 CUL1 16009132 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ZC3HC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ZC3HC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ZC3HC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ZC3HC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CHEK1 ZC3HC1 22135298 phosphorylation N/A PhosphoSite
CDK1 ZC3HC1 22135298 phosphorylation N/A PhosphoSite
CDK2 ZC3HC1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
CDC5L ZC3HC1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GPX7 ZC3HC1 25348397 N/A physical interaction ComPPI
YWHAG ZC3HC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SKP1 ZC3HC1 25348397 N/A physical interaction ComPPI
H2BC4 ZC3HC1 25348397 N/A physical interaction ComPPI
MAPK1 ZC3HC1 25348397 N/A physical interaction ComPPI
MAPK3 ZC3HC1 25348397 N/A physical interaction ComPPI
FZR1 ZC3HC1 25348397 N/A physical interaction ComPPI
GRN ZC3HC1 25348397 N/A physical interaction ComPPI
RBX1 ZC3HC1 25348397 N/A physical interaction ComPPI
PFKL ZC3HC1 25348397 N/A physical interaction ComPPI
PDPK1 ZC3HC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLK1 ZC3HC1 25348397 N/A physical interaction ComPPI
NXF2 ZC3HC1 25348397 N/A physical interaction ComPPI
TNFSF11 ZC3HC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TPR ZC3HC1 25348397 N/A physical interaction ComPPI
CUL1 ZC3HC1 25348397 N/A physical interaction ComPPI
YWHAE ZC3HC1 25348397 N/A physical interaction ComPPI
CCNB1 ZC3HC1 25348397 N/A physical interaction ComPPI
GTF3C4 ZC3HC1 25348397 N/A physical interaction ComPPI
TRIP13 ZC3HC1 25348397 N/A physical interaction ComPPI
TSC22D1 ZC3HC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ALK ZC3HC1 25348397 N/A physical interaction ComPPI
HNRNPA1 ZC3HC1 25348397 N/A physical interaction ComPPI
SALL2 ZC3HC1 25348397 N/A physical interaction ComPPI
AASDHPPT ZC3HC1 25348397 N/A physical interaction ComPPI
MINDY3 ZC3HC1 25348397 N/A physical interaction ComPPI
RPL38 ZC3HC1 25348397 N/A physical interaction ComPPI
H2BC11 ZC3HC1 25348397 N/A physical interaction ComPPI
APP ZC3HC1 25348397 N/A physical interaction ComPPI
EHD4 ZC3HC1 25348397 N/A physical interaction ComPPI
SRBD1 ZC3HC1 25348397 N/A physical interaction ComPPI
SASS6 ZC3HC1 25348397 N/A physical interaction ComPPI
ZC3HC1 ATP6V1C2 25348397 N/A physical interaction ComPPI
ZC3HC1 TAFA3 25348397 N/A physical interaction ComPPI
ZC3HC1 ETNPPL 25348397 N/A physical interaction ComPPI
CDK2 ZC3HC1 17389604 27898060 inhibition N/A OmniPath
CDK1 ZC3HC1 17389604 27898060 inhibition N/A OmniPath
ALK ZC3HC1 12748172 27898060 N/A N/A OmniPath

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