GENE:ZNF622
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ZNF622 |
| FullNmae | zinc finger protein 622 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:30958 |
| EnsembleID | ENSG00000173545 |
| Uniprot | Q969S3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ZNF622 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ZNF622 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ZNF622 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ZNF622 | GO:0003723,GO:0005515,GO:0005654,GO:0005730,GO:0005794,GO:0005829,GO:0008270,GO:0008631,GO:0030687,GO:0033674,GO:0042273,GO:0042273,GO:0043065,GO:0043410,GO:0046330,GO:1990275 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ZNF622 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ZNF622 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ZNF622 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ZNF622 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ZNF622 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ZNF622 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ZNF622 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ZNF622 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ZNF622 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ZNF622 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ZNF622 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | ZNF622 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000475586 | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BC299 | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E6EFA | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E1509 | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E628F | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | ZNF622 | 20371350 21572407 22473208 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | ZNF622 | 20371350 21572407 22473208 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | ZNF622 | 20371350 21572407 22473208 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | ZNF622 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D8730 | ZNF622 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000136174 | ZNF622 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MAP3K5 | ZNF622 | 22135298 | phosphorylation | N/A | PhosphoSite |
| MYBL2 | ZNF622 | 25361965 | interaction type | N/A | PTMCode2 |
| ZNF622 | MYBL2 | 25361965 | interaction type | N/A | PTMCode2 |
| MELK | ZNF622 | 25361965 | interaction type | N/A | PTMCode2 |
| ZNF622 | MELK | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NPM1 | ZNF622 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LCA5 | ZNF622 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| PPP1R2B | ZNF622 | 25348397 | N/A | physical interaction | ComPPI |
| ERBB2 | ZNF622 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RPL10 | ZNF622 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PAXIP1 | ZNF622 | 25348397 | N/A | physical interaction | ComPPI |
| MYBL2 | ZNF622 | 12645566 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| MAP3K5 | ZNF622 | 21771788 24234451 25348397 | phosphorylation reaction,association,physical association | anti bait coimmunoprecipitation,pull down,in-gel kinase assay,comigration in gel electrophoresis | ComPPI,IntAct |
| HNRNPU | ZNF622 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DCTN1 | ZNF622 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| EIF6 | ZNF622 | 25348397 | N/A | physical interaction | ComPPI |
| MELK | ZNF622 | 11802789 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| HIF1AN | ZNF622 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| HECTD1 | ZNF622 | 25348397 | N/A | physical interaction | ComPPI |
| YAF2 | ZNF622 | 25348397 | N/A | physical interaction | ComPPI |
| CAVIN1 | ZNF622 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | OAS3 | 21903422 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ZNF622 | APP | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | WDR33 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | EFTUD2 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | RBM28 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | GLA | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | UBFD1 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | G6PD | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | NPEPPS | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | PPP1R2 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | SCLY | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | FTSJ3 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | POP1 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | STAU1 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | DNAJC21 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | LSG1 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | MMTAG2 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | NMD3 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | NOC3L | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | NEMF | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | BRIX1 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | KRR1 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | MRTO4 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | EIF2B4 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | CEP128 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| ZNF622 | CNTRL | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| ZNF622 | CCDC102B | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | PRPF31 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF622 | FOS | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| ZNF622 | MACROH2A1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| EBNA1BP2 | ZNF622 | 25348397 | N/A | physical interaction | ComPPI |
| HSCB | ZNF622 | 24234451 25348397 28380382 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| ZNF622 | ZNF622 | 11802789 14525934 | N/A | experimental interaction detection,two hybrid | HPRD |
| MAP3K5 | ZNF622 | 21771788 27898060 | stimulant | N/A | OmniPath |
