Gene Information gene info

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GENE：CXCR3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CXCR3
FullNmae C-X-C motif chemokine receptor 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4540
EnsembleID ENSG00000186810
Uniprot P49682

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CXCR3 immunogenic 37275552 To identify genes associated with ICD, we collected 34 ICD-related genes from previously reported literature. retulator signature

Go Annotation:

GeneSymbol Go id
CXCR3 GO:0001525,GO:0002685,GO:0004950,GO:0005515,GO:0005737,GO:0005886,GO:0006915,GO:0006935,GO:0006954,GO:0006955,GO:0007155,GO:0007166,GO:0007186,GO:0007204,GO:0009897,GO:0009986,GO:0016493,GO:0016494,GO:0019722,GO:0019956,GO:0019957,GO:0030155,GO:0060326,GO:0070098

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CXCR3 hsa:2833 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
CXCR3 hsa:2833 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)
CXCR3 hsa:2833 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LASP1 CXCR3 20419088 23180781 physical association pull down InnateDB
TBX21 CXCR3 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB
GATA3 CXCR3 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CXCR3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CXCR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CXCR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CXCR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CXCR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CXCR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TBX21 CXCR3 14500650 21540308 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CCL11 CXCR3 25361965 interaction type N/A PTMCode2
CXCR3 CCL11 25361965 interaction type N/A PTMCode2
CXCL11 CXCR3 25361965 interaction type N/A PTMCode2
CXCR3 CXCL11 25361965 interaction type N/A PTMCode2
CCL5 CXCR3 25361965 interaction type N/A PTMCode2
CXCR3 CCL5 25361965 interaction type N/A PTMCode2
PF4 CXCR3 25361965 interaction type N/A PTMCode2
CXCR3 PF4 25361965 interaction type N/A PTMCode2
CCL7 CXCR3 25361965 interaction type N/A PTMCode2
CXCR3 CCL7 25361965 interaction type N/A PTMCode2
CCL13 CXCR3 25361965 interaction type N/A PTMCode2
CXCR3 CCL13 25361965 interaction type N/A PTMCode2
CXCL9 CXCR3 25361965 interaction type N/A PTMCode2
CXCR3 CXCL9 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CXCL9 CXCR3 25348397 N/A experimental interaction detection,physical interaction,physical interaction,biochemical,in vitro,in vivo ComPPI
TMEM14A CXCR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PF4 CXCR3 25348397 N/A physical interaction,in vitro ComPPI
CXCR3 CXCL13 25348397 N/A physical interaction,in vitro,in vivo ComPPI
CXCR3 CXCL10 25348397 N/A experimental interaction detection,physical interaction,physical interaction,biochemical,in vitro,in vivo ComPPI
CXCR3 CCL11 25348397 N/A physical interaction,biochemical ComPPI
CXCR3 CCL13 25348397 N/A physical interaction,biochemical ComPPI
CXCR3 CCL5 25348397 N/A physical interaction,biochemical ComPPI
CXCR3 C2CD2L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CXCL11 CXCR3 25348397 N/A experimental interaction detection,physical interaction,physical interaction,biochemical,in vitro,in vivo ComPPI
CCL7 CXCR3 25348397 N/A physical interaction,biochemical ComPPI
CXCL12 CXCR3 27898060 9660793 stimulant N/A OmniPath
CCL5 CXCR3 27898060 9660793 stimulant N/A OmniPath
CXCL11 CXCR3 11259614 15273303 15761110 16189514 24218476 27898060 9625760 stimulant N/A OmniPath
CXCL10 CXCR3 10233762 12571234 15761110 24218476 27898060 9064356 9625760 9660793 stimulant N/A OmniPath
CXCL9 CXCR3 11259614 12782716 15761110 24218476 27898060 9625760 9660793 stimulant N/A OmniPath
CCL11 CXCR3 27898060 9660793 stimulant N/A OmniPath
CXCR3 LASP1 20419088 27898060 N/A N/A OmniPath
CCL21 CXCR3 11907075 27898060 stimulant N/A OmniPath
PF4 CXCR3 12782716 24218476 27898060 stimulant N/A OmniPath
CCL13 CXCR3 27898060 9660793 stimulant N/A OmniPath
CCL20 CXCR3 27898060 9660793 stimulant N/A OmniPath
CCL19 CXCR3 27898060 9660793 stimulant N/A OmniPath
CCL7 CXCR3 27898060 9660793 stimulant N/A OmniPath

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