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GENE：NT5E

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NT5E
FullNmae 5'-nucleotidase ecto
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8021
EnsembleID ENSG00000135318
Uniprot P21589

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NT5E immunogenic 37275552 To identify genes associated with ICD, we collected 34 ICD-related genes from previously reported literature. retulator signature

Go Annotation:

GeneSymbol Go id
NT5E GO:0000166,GO:0002953,GO:0005515,GO:0005654,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0006196,GO:0006259,GO:0007159,GO:0008253,GO:0008253,GO:0008253,GO:0008270,GO:0009897,GO:0009986,GO:0010035,GO:0016020,GO:0033198,GO:0042802,GO:0046032,GO:0046034,GO:0046086,GO:0050340,GO:0050483,GO:0050484,GO:0050728,GO:0055074,GO:0070062,GO:0106411,GO:0140928

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NT5E hsa:4907 path:hsa00230 Purine metabolism - Homo sapiens (human)
NT5E hsa:4907 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
NT5E hsa:4907 path:hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human)
NT5E hsa:4907 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NT5E hsa:4907 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 NT5E 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NT5E 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 NT5E 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NT5E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NT5E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NT5E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NT5E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NT5E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NT5E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 NT5E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NT5E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A NT5E 12370277 trascriptional regulation,stimulation inferred by curator TFlink
HNF1A NT5E 10428853 trascriptional regulation,stimulation inferred by curator TFlink
LEF1 NT5E 10428853 trascriptional regulation,stimulation inferred by curator TFlink
SP1 NT5E 10428853 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 NT5E 10428853 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 NT5E N/A trascriptional regulation,stimulation inferred by curator TFlink
ATF2 NT5E N/A trascriptional regulation,stimulation inferred by curator TFlink
ESR1 NT5E N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A NT5E N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 NT5E N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 NT5E 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS0000065D58 NT5E 18668040 25416803 28158983 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000EED18 NT5E 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
PLAA NT5E 25348397 N/A physical interaction ComPPI
SCAMP1 NT5E 25348397 N/A physical interaction ComPPI
ARL8A NT5E 25348397 N/A physical interaction ComPPI
GNL3L NT5E 25348397 N/A physical interaction ComPPI
RHOG NT5E 25348397 N/A physical interaction ComPPI
ATR NT5E 25348397 N/A physical interaction ComPPI
SLC6A8 NT5E 25348397 N/A physical interaction ComPPI
RFC2 NT5E 25348397 N/A physical interaction ComPPI
AFF1 NT5E 25348397 N/A physical interaction ComPPI
SYNJ2BP NT5E 25348397 N/A physical interaction ComPPI
NR2F2 NT5E 25348397 N/A physical interaction ComPPI
RAB11A NT5E 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
GLMN NT5E 25348397 N/A physical interaction ComPPI
RAB9A NT5E 25348397 N/A physical interaction ComPPI
CXCR4 NT5E 25348397 N/A physical interaction ComPPI
VANGL2 NT5E 25348397 N/A physical interaction ComPPI
MTOR NT5E 25348397 N/A physical interaction ComPPI
STEAP3 NT5E 25348397 N/A physical interaction ComPPI
TNPO2 NT5E 25348397 N/A physical interaction ComPPI
ARL2 NT5E 25348397 N/A physical interaction ComPPI
PCDH7 NT5E 25348397 N/A physical interaction ComPPI
XPO7 NT5E 25348397 N/A physical interaction ComPPI
RPTOR NT5E 25348397 N/A physical interaction ComPPI
CAT NT5E 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SLC16A2 NT5E 25348397 N/A physical interaction ComPPI
GJA1 NT5E 25348397 N/A physical interaction ComPPI
ADIPOR1 NT5E 25348397 N/A physical interaction ComPPI
DNAAF5 NT5E 25348397 N/A physical interaction ComPPI
DEGS1 NT5E 25348397 N/A physical interaction ComPPI
ARF5 NT5E 25348397 N/A physical interaction ComPPI
PDS5A NT5E 25348397 N/A physical interaction ComPPI
USP22 NT5E 25348397 N/A physical interaction ComPPI
USP3 NT5E 25348397 N/A physical interaction ComPPI
USP36 NT5E 25348397 N/A physical interaction ComPPI
ZNRF4 NT5E 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NT5E SLC30A5 25348397 N/A physical interaction ComPPI
NT5E NDUFA2 25348397 N/A physical interaction ComPPI
NT5E TMEM177 25348397 N/A physical interaction ComPPI
NT5E CHD1L 25348397 N/A physical interaction ComPPI
NT5E FLVCR1 25348397 N/A physical interaction ComPPI
NT5E RDH13 25348397 N/A physical interaction ComPPI
NT5E HSDL1 25348397 N/A physical interaction ComPPI
NT5E GHITM 25348397 N/A physical interaction ComPPI
NT5E SLC7A2 25348397 N/A physical interaction ComPPI
NT5E SLC41A1 25348397 N/A physical interaction ComPPI
NT5E SLC47A1 25348397 N/A physical interaction ComPPI
NT5E SAR1B 25348397 N/A physical interaction ComPPI
NT5E SLC44A1 25348397 N/A physical interaction ComPPI
NT5E SLC26A6 25348397 N/A physical interaction ComPPI
NT5E CYP2S1 25348397 N/A physical interaction ComPPI
NT5E TMEM192 25348397 N/A physical interaction ComPPI
NT5E ACTB 10470109 14525934 N/A experimental interaction detection HPRD
LAMA1 NT5E 10470109 14525934 N/A experimental interaction detection HPRD
NT5E FN1 10470109 14525934 27898060 9361795 N/A experimental interaction detection HPRD,OmniPath

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