GENE:NT5E
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | NT5E |
FullNmae | 5'-nucleotidase ecto |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:8021 |
EnsembleID | ENSG00000135318 |
Uniprot | P21589 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
NT5E | immunogenic | 37275552 | To identify genes associated with ICD, we collected 34 ICD-related genes from previously reported literature. | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
NT5E | GO:0000166,GO:0002953,GO:0005515,GO:0005654,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0006196,GO:0006259,GO:0007159,GO:0008253,GO:0008253,GO:0008253,GO:0008270,GO:0009897,GO:0009986,GO:0010035,GO:0016020,GO:0033198,GO:0042802,GO:0046032,GO:0046034,GO:0046086,GO:0050340,GO:0050483,GO:0050484,GO:0050728,GO:0055074,GO:0070062,GO:0106411,GO:0140928 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
NT5E | hsa:4907 | path:hsa00230 | Purine metabolism - Homo sapiens (human) |
NT5E | hsa:4907 | path:hsa00240 | Pyrimidine metabolism - Homo sapiens (human) |
NT5E | hsa:4907 | path:hsa00760 | Nicotinate and nicotinamide metabolism - Homo sapiens (human) |
NT5E | hsa:4907 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
NT5E | hsa:4907 | path:hsa01232 | Nucleotide metabolism - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | NT5E | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
FOXP3 | NT5E | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | NT5E | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | NT5E | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | NT5E | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | NT5E | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | NT5E | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | NT5E | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | NT5E | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | NT5E | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HIF1A | NT5E | 12370277 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF1A | NT5E | 10428853 | trascriptional regulation,stimulation | inferred by curator | TFlink |
LEF1 | NT5E | 10428853 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SP1 | NT5E | 10428853 | trascriptional regulation,stimulation | inferred by curator | TFlink |
DAND5 | NT5E | 10428853 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ATF1 | NT5E | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
ATF2 | NT5E | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
ESR1 | NT5E | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
TFAP2A | NT5E | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000338542 | NT5E | N/A | rna interference,inhibition | experimental interaction detection | miRSponge |
URS0000338542 | NT5E | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
URS0000065D58 | NT5E | 18668040 25416803 28158983 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS00000EED18 | NT5E | 21566225 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PLAA | NT5E | 25348397 | N/A | physical interaction | ComPPI |
SCAMP1 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
ARL8A | NT5E | 25348397 | N/A | physical interaction | ComPPI |
GNL3L | NT5E | 25348397 | N/A | physical interaction | ComPPI |
RHOG | NT5E | 25348397 | N/A | physical interaction | ComPPI |
ATR | NT5E | 25348397 | N/A | physical interaction | ComPPI |
SLC6A8 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
RFC2 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
AFF1 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
SYNJ2BP | NT5E | 25348397 | N/A | physical interaction | ComPPI |
NR2F2 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
RAB11A | NT5E | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
GLMN | NT5E | 25348397 | N/A | physical interaction | ComPPI |
RAB9A | NT5E | 25348397 | N/A | physical interaction | ComPPI |
CXCR4 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
VANGL2 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
MTOR | NT5E | 25348397 | N/A | physical interaction | ComPPI |
STEAP3 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
TNPO2 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
ARL2 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
PCDH7 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
XPO7 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
RPTOR | NT5E | 25348397 | N/A | physical interaction | ComPPI |
CAT | NT5E | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
SLC16A2 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
GJA1 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
ADIPOR1 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
DNAAF5 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
DEGS1 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
ARF5 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
PDS5A | NT5E | 25348397 | N/A | physical interaction | ComPPI |
USP22 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
USP3 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
USP36 | NT5E | 25348397 | N/A | physical interaction | ComPPI |
ZNRF4 | NT5E | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
NT5E | SLC30A5 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | NDUFA2 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | TMEM177 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | CHD1L | 25348397 | N/A | physical interaction | ComPPI |
NT5E | FLVCR1 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | RDH13 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | HSDL1 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | GHITM | 25348397 | N/A | physical interaction | ComPPI |
NT5E | SLC7A2 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | SLC41A1 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | SLC47A1 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | SAR1B | 25348397 | N/A | physical interaction | ComPPI |
NT5E | SLC44A1 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | SLC26A6 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | CYP2S1 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | TMEM192 | 25348397 | N/A | physical interaction | ComPPI |
NT5E | ACTB | 10470109 14525934 | N/A | experimental interaction detection | HPRD |
LAMA1 | NT5E | 10470109 14525934 | N/A | experimental interaction detection | HPRD |
NT5E | FN1 | 10470109 14525934 27898060 9361795 | N/A | experimental interaction detection | HPRD,OmniPath |