Gene Information gene info

  1. Home

GENE：ARNT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARNT
FullNmae aryl hydrocarbon receptor nuclear translocator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:700
EnsembleID ENSG00000143437
Uniprot P27540

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARNT pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARNT ferroptosis 36166594 However, the impact of melatonin on liver protection and anti-ferroptosis was offset upon brain and muscle ARNT-like 1 (BMAL1) knockdown with the notably blocked Nrf2-ARE pathway. retulator signature

Go Annotation:

GeneSymbol Go id
ARNT GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0000987,GO:0001666,GO:0001892,GO:0001938,GO:0003700,GO:0004879,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0006357,GO:0010575,GO:0016604,GO:0017162,GO:0030154,GO:0030522,GO:0030949,GO:0033235,GO:0034751,GO:0034753,GO:0042803,GO:0043565,GO:0043619,GO:0045648,GO:0045821,GO:0045944,GO:0046886,GO:0046982,GO:0046982,GO:0050728,GO:0061629,GO:0090575,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARNT hsa:405 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
ARNT hsa:405 path:hsa04148 Efferocytosis - Homo sapiens (human)
ARNT hsa:405 path:hsa04934 Cushing syndrome - Homo sapiens (human)
ARNT hsa:405 path:hsa05200 Pathways in cancer - Homo sapiens (human)
ARNT hsa:405 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
ARNT hsa:405 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
ARNT hsa:405 path:hsa05211 Renal cell carcinoma - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AHR ARNT 17823304 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD4 ARNT 11486006 23180781 physical association electrophoretic mobility supershift assay InnateDB
HIF1A ARNT 11486006 16126907 17277313 23180781 physical association electrophoretic mobility supershift assay InnateDB
HIF3A ARNT 16126907 23180781 physical association anti tag coimmunoprecipitation InnateDB
ARNT HIF1AN 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
ARNT EGLN3 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
ARNT EGLN1 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
ARNT EGLN2 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ARNT 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 ARNT 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 ARNT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ARNT 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ARNT 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ARNT 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 ARNT 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 ARNT 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ARNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ARNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ARNT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AHR ARNT 19255421 8631989 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A ARNT 12239177 trascriptional regulation,stimulation inferred by curator TFlink
PHB2 ARNT 21256954 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ARNT N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000008F0CF ARNT 20308559 rna interference,inhibition experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000008F0CF ARNT 20308559 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000070B1D ARNT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D ARNT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 ARNT 24329418 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS0000425000 ARNT 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000753AD ARNT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 ARNT 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 ARNT 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 ARNT 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
NPAS4 ARNT 25361965 interaction type N/A PTMCode2
ARNT NPAS4 25361965 interaction type N/A PTMCode2
NCOA1 ARNT 25361965 interaction type N/A PTMCode2
ARNT NCOA1 25361965 interaction type N/A PTMCode2
ARNT CSNK2A1 25361965 interaction type N/A PTMCode2
SIM2 ARNT 25361965 interaction type N/A PTMCode2
ARNT SIM2 25361965 interaction type N/A PTMCode2
PTGES3 ARNT 25361965 interaction type N/A PTMCode2
ARNT PTGES3 25361965 interaction type N/A PTMCode2
BRCA1 ARNT 25361965 interaction type N/A PTMCode2
ARNT BRCA1 25361965 interaction type N/A PTMCode2
AHR ARNT 25361965 interaction type N/A PTMCode2
ARNT AHR 25361965 interaction type N/A PTMCode2
EPAS1 ARNT 25361965 interaction type N/A PTMCode2
ARNT EPAS1 25361965 interaction type N/A PTMCode2
HIF1A ARNT 25361965 interaction type N/A PTMCode2
ARNT HIF1A 25361965 interaction type N/A PTMCode2
SIM1 ARNT 25361965 interaction type N/A PTMCode2
ARNT SIM1 25361965 interaction type N/A PTMCode2
HSP90AA1 ARNT 25361965 interaction type N/A PTMCode2
ARNT HSP90AA1 25361965 interaction type N/A PTMCode2
AIP ARNT 25361965 interaction type N/A PTMCode2
ARNT AIP 25361965 interaction type N/A PTMCode2
AHRR ARNT 25361965 interaction type N/A PTMCode2
ARNT AHRR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIAS2 ARNT 25348397 N/A physical interaction ComPPI
HSPA8 ARNT 25348397 N/A physical interaction ComPPI
GMNN ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LDHA ARNT 25348397 N/A physical interaction ComPPI
C1QTNF2 ARNT 25348397 N/A physical interaction ComPPI
CASP9 ARNT 25348397 N/A physical interaction ComPPI
FOXR2 ARNT 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HEY2 ARNT 10692439 14525934 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
EGLN3 ARNT 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TACC3 ARNT 25348397 N/A physical interaction ComPPI
SP1 ARNT 25348397 N/A physical interaction ComPPI
CASP3 ARNT 25348397 N/A physical interaction ComPPI
JUN ARNT 25348397 N/A physical interaction ComPPI
RB1 ARNT 25348397 N/A physical interaction ComPPI
GTF2F2 ARNT 14525934 25348397 8794892 N/A experimental interaction detection,physical interaction ComPPI,HPRD
NCOA1 ARNT 10594042 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EP300 ARNT 10999956 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
HIF1A ARNT 14525934 19168635 20562859 20603618 20932347 21620138 24234451 24434214 25348397 9079689 9704006 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
TGM2 ARNT 25348397 N/A physical interaction ComPPI
BCAT1 ARNT 25348397 N/A physical interaction ComPPI
NCOR2 ARNT 10395741 24234451 25348397 association,physical association coimmunoprecipitation,physical interaction ComPPI,IntAct
AIP ARNT 25348397 N/A physical interaction ComPPI
PFKM ARNT 25348397 N/A physical interaction ComPPI
HSP90AA1 ARNT 25348397 N/A physical interaction ComPPI
LSM8 ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD9 ARNT 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PTGES3 ARNT 11879970 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
STRBP ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HEY1 ARNT 10692439 14525934 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
TNFAIP1 ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CALCOCO1 ARNT 25348397 N/A physical interaction ComPPI
AHR ARNT 10395741 11768231 12024042 14525934 24234451 25348397 7488247 7628454 8384309 9704006 association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,IntAct
TRIP11 ARNT 14525934 15485806 25348397 27898060 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
NCOA2 ARNT 12024042 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CUL2 ARNT 25348397 N/A physical interaction ComPPI
GTF2F1 ARNT 25348397 N/A physical interaction ComPPI
HNF4A ARNT 25348397 N/A physical interaction ComPPI
MTA3 ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ELOB ARNT 25348397 N/A physical interaction ComPPI
HIF1AN ARNT 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
DIABLO ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IRAK4 ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PDK1 ARNT 25348397 N/A physical interaction ComPPI
ELAVL1 ARNT 25348397 N/A physical interaction ComPPI
ESR1 ARNT 14525934 15837795 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
BRCA1 ARNT 16567799 25348397 27898060 N/A physical interaction ComPPI,OmniPath
AKT1 ARNT 25348397 N/A physical interaction ComPPI
PML ARNT 12354770 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EPAS1 ARNT 11018023 14525934 19129502 23434853 24234451 25348397 9079689 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,nuclear magnetic resonance,x-ray crystallography,physical interaction,amplified luminescent proximity homogeneous assay,two hybrid ComPPI,HPRD,IntAct
NPAS4 ARNT 14525934 14701734 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
SHMT1 ARNT 25348397 N/A physical interaction ComPPI
SIM2 ARNT 11782478 14525934 14701734 25348397 27898060 9020169 9271372 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
CREB1 ARNT 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HK1 ARNT 25348397 N/A physical interaction ComPPI
NCOA7 ARNT 10395741 24234451 25348397 association,physical association coimmunoprecipitation,physical interaction ComPPI,IntAct
ADH5 ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SIM1 ARNT 14525934 25348397 9020169 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
SLX1A ARNT 25348397 N/A physical interaction ComPPI
HERC2 ARNT 25348397 N/A physical interaction ComPPI
ARNT DCAF15 25348397 N/A physical interaction ComPPI
ARNT HERC2P3 25348397 N/A physical interaction ComPPI
ARNT FOXN1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ARNT TUBB2A 25348397 N/A physical interaction ComPPI
ARNT NPAS1 25348397 N/A physical interaction ComPPI
ARNT CIAO3 25348397 N/A physical interaction ComPPI
ARNT HSP90AA2P 25348397 N/A physical interaction ComPPI
ARNT PFKFB3 25348397 N/A physical interaction ComPPI
ARNT PFKFB4 25348397 N/A physical interaction ComPPI
ARNT ARNT2 14525934 8927054 N/A two hybrid HPRD
CSNK2A1 ARNT 14525934 16129408 N/A experimental interaction detection HPRD
UBE2I ARNT 12354770 14525934 N/A experimental interaction detection HPRD
ARNT ARNT 11502749 12354770 14525934 24234451 9704006 physical association two hybrid,experimental interaction detection HPRD,IntAct
SENP6 ARNT 12354770 14525934 N/A experimental interaction detection HPRD
AHRR ARNT 14525934 9887096 N/A experimental interaction detection,two hybrid HPRD
TXN ARNT 19737086 27898060 stimulant N/A OmniPath
STAT1 ARNT 19646959 27898060 stimulant N/A OmniPath
CREBBP ARNT 12573436 27898060 stimulant N/A OmniPath
APEX1 ARNT 10671489 27898060 stimulant N/A OmniPath
UBE2I ARNT 12354770 27898060 N/A N/A OmniPath
EP300 ARNT 10999956 12573436 27898060 stimulant N/A OmniPath
CSNK2A1 ARNT 16129408 18669648 27898060 inhibition,stimulant N/A OmniPath
ARNT HIF1A 11782478 11829741 15319539 15347669 16126907 20049704 20562859 20603618 20932347 21435239 21620138 26496610 27898060 8816435 8927054 9079689 9704006 N/A N/A OmniPath
HIF1A ARNT 11782478 11829741 15319539 15347669 16126907 20049704 20562859 20603618 20932347 21435239 21620138 26496610 27898060 8816435 8927054 9079689 9704006 N/A N/A OmniPath
SENP6 ARNT 12354770 27898060 N/A N/A OmniPath

Visualization










  Return