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GENE：CKB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CKB
FullNmae creatine kinase B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1991
EnsembleID ENSG00000166165
Uniprot P12277

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CKB ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CKB GO:0004111,GO:0004111,GO:0005515,GO:0005524,GO:0005615,GO:0005739,GO:0005829,GO:0005829,GO:0005886,GO:0016310,GO:0021762,GO:0031625,GO:0046314,GO:0070062,GO:0140651

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CKB hsa:1152 path:hsa00330 Arginine and proline metabolism - Homo sapiens (human)
CKB hsa:1152 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 CKB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CKB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CKB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000033EBB8 CKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE CKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000052E1A6 CKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000134ADC CKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D CKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD CKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 CKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000239117 CKB 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002E99CB CKB 25416803 25601461 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000003575B CKB 25416803 25601461 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PAK2 CKB 25348397 N/A physical interaction ComPPI
PPP1CC CKB 25348397 N/A physical interaction ComPPI
LDHB CKB 25348397 N/A physical interaction ComPPI
ALDOC CKB 25348397 N/A physical interaction ComPPI
CKB USP15 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CKB HDAC5 25348397 N/A physical interaction ComPPI
CKB PSMA3 25348397 N/A physical interaction ComPPI
CKB ILK 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CKB TAB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CKB PPP1CA 22321011 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CKB SIRT7 25348397 N/A physical interaction ComPPI
CKB TERF1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
CKB TINF2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
CKB ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
CKB POT1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
CKB CUL3 25348397 N/A physical interaction ComPPI
CKB CDK2 25348397 N/A physical interaction ComPPI
CKB CUL1 25348397 N/A physical interaction ComPPI
CKB AKT1 25348397 N/A physical interaction ComPPI
CKB PLA2G4A 25348397 N/A physical interaction ComPPI
CKB TRAF3IP1 20391533 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CKB IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CKB MLH1 20706999 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CKB RAD52 19338310 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CKB CSE1L 25348397 N/A physical interaction ComPPI
CKB DFFA 25348397 N/A physical interaction ComPPI
CKB DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CKB EEF2 25348397 N/A physical interaction ComPPI
CKB HMGB2 25348397 N/A physical interaction ComPPI
CKB RRAGB 25348397 N/A physical interaction ComPPI
CKB SLC9A3R1 25348397 N/A physical interaction ComPPI
CKB TBCB 25348397 N/A physical interaction ComPPI
CKB G6PD 25348397 N/A physical interaction ComPPI
CKB TGM2 25348397 N/A physical interaction ComPPI
CKB UBFD1 25348397 N/A physical interaction ComPPI
CKB YWHAG 25348397 N/A physical interaction ComPPI
CKB ASB16 25348397 N/A physical interaction ComPPI
CKB TRIM63 25348397 N/A physical interaction ComPPI
CKB HUWE1 25348397 N/A physical interaction ComPPI
CKB FUS 25348397 N/A physical interaction ComPPI
CKB MOV10 25348397 N/A physical interaction ComPPI
CKB CUL7 25348397 N/A physical interaction ComPPI
CKB OBSL1 25348397 N/A physical interaction ComPPI
CKB ACO2 25348397 N/A physical interaction ComPPI
CKB ACTN1 25348397 N/A physical interaction ComPPI
CKB ACTN4 25348397 N/A physical interaction ComPPI
CKB ALDOA 25348397 N/A physical interaction ComPPI
CKB CAST 25348397 N/A physical interaction ComPPI
CKB TPM1 25348397 N/A physical interaction ComPPI
CKB TPM3 25348397 N/A physical interaction ComPPI
CKB DDX10 25348397 N/A physical interaction ComPPI
CKB TPM4 25348397 N/A physical interaction ComPPI
CKB NTRK1 25348397 N/A physical interaction ComPPI
CKB CNTROB 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CKB CENPJ 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CKB DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CKB DNM1L 24234451 25348397 29128334 colocalization,association cross-linking study,physical interaction,fluorescence microscopy ComPPI,IntAct
CKB SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CKB SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CKB VDAC1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CKB KEAP1 25348397 N/A physical interaction ComPPI
CKB TARDBP 25348397 N/A physical interaction ComPPI
CKB MAPK13 19135240 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CKB MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CKB GABARAPL2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CKB GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CKB SF1 24234451 25348397 26420826 association anti bait coimmunoprecipitation ComPPI,IntAct
CKB OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
CKB JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CKB PPP2R1A 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CKB PPTC7 24234451 25348397 28330616 association pull down ComPPI,IntAct
CKB PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
CKB RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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