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GENE：GLP1R

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GLP1R
FullNmae glucagon like peptide 1 receptor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4324
EnsembleID ENSG00000112164
Uniprot P43220

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GLP1R ferroptosis 38732142 GLP1R stimulation inhibits apoptosis, necroptosis, pyroptosis, and ferroptosis of cardiomyocytes. retulator signature

Go Annotation:

GeneSymbol Go id
GLP1R GO:0004888,GO:0004967,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0007166,GO:0007189,GO:0007189,GO:0007190,GO:0007204,GO:0007611,GO:0008016,GO:0016020,GO:0017046,GO:0019933,GO:0031204,GO:0044508,GO:0044508,GO:0045776,GO:0045777,GO:0046879,GO:0071377,GO:1990911

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GLP1R hsa:2740 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
GLP1R hsa:2740 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
GLP1R hsa:2740 path:hsa04911 Insulin secretion - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 GLP1R 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GLP1R 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GLP1R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GLP1R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GLP1R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GLP1R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 GLP1R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 GLP1R N/A trascriptional regulation,stimulation inferred by curator TFlink
SP3 GLP1R N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001CF056 GLP1R 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075E2C3 GLP1R 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002F0130 GLP1R 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001A6D0C GLP1R 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A GLP1R 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 GLP1R 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 GLP1R 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031F6C2 GLP1R 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000028DE3F GLP1R 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KRTAP5-9 GLP1R 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-8 GLP1R 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP10-7 GLP1R 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GLP1R GPRASP1 14525934 15452121 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GLP1R GCG 11116211 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
GLP1R SUMO1 25348397 N/A physical interaction ComPPI
GLP1R AP2M1 25348397 N/A physical interaction ComPPI
GLP1R APH1A 25348397 N/A physical interaction ComPPI
GLP1R APLP1 25348397 N/A physical interaction ComPPI
GLP1R ARFRP1 25348397 N/A physical interaction ComPPI
GLP1R ATP6V0B 25348397 N/A physical interaction ComPPI
GLP1R CD81 25348397 N/A physical interaction ComPPI
GLP1R CFI 25348397 N/A physical interaction ComPPI
GLP1R ELOVL1 25348397 N/A physical interaction ComPPI
GLP1R ERP29 25348397 N/A physical interaction ComPPI
GLP1R GPR37 25348397 N/A physical interaction ComPPI
GLP1R IFITM3 25348397 N/A physical interaction ComPPI
GLP1R MYL6 25348397 N/A physical interaction ComPPI
GLP1R NRGN 25348397 N/A physical interaction ComPPI
GLP1R NUCKS1 25348397 N/A physical interaction ComPPI
GLP1R STMN1 25348397 N/A physical interaction ComPPI
GLP1R STMN3 25348397 N/A physical interaction ComPPI
GLP1R STOML2 25348397 N/A physical interaction ComPPI
GLP1R KRTAP10-9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GLP1R KRTAP10-3 25348397 N/A physical interaction ComPPI
GLP1R TMBIM6 25348397 N/A physical interaction ComPPI
GLP1R CLIP4 25348397 N/A physical interaction ComPPI
GLP1R CLDN7 25348397 N/A physical interaction ComPPI
GLP1R DAD1 25348397 N/A physical interaction ComPPI
GLP1R GNAS 25348397 N/A physical interaction ComPPI
GLP1R GNAS 25348397 N/A physical interaction ComPPI
GLP1R PAM 25348397 N/A physical interaction ComPPI
GLP1R RTN4 25348397 N/A physical interaction ComPPI
GLP1R TM4SF4 25348397 N/A physical interaction ComPPI
GLP1R AIG1 25348397 N/A physical interaction ComPPI
GLP1R MT-ND4L 25348397 N/A physical interaction ComPPI
GLP1R ATP6AP2 25348397 N/A physical interaction ComPPI
GLP1R ARRB1 18445652 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CALM1 GLP1R 25348397 N/A pull down ComPPI
CALM2 GLP1R 14525934 15670850 24234451 physical association experimental interaction detection,pull down HPRD,IntAct
GLP1R ATP5F1A 24234451 30021884 physical association cross-linking study IntAct
GCG GLP1R 11116211 18248821 27898060 7937318 8404634 stimulant N/A OmniPath

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