Gene Information gene info

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GENE：MS4A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MS4A1
FullNmae membrane spanning 4-domains A1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7315
EnsembleID ENSG00000156738
Uniprot P11836

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MS4A1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MS4A1 GO:0002115,GO:0005154,GO:0005515,GO:0005615,GO:0005654,GO:0005886,GO:0005886,GO:0005886,GO:0006959,GO:0007166,GO:0009617,GO:0009897,GO:0009986,GO:0019865,GO:0023026,GO:0030183,GO:0042100,GO:0042113,GO:0042802,GO:0044853,GO:0050853,GO:0051262,GO:0070062,GO:1902656,GO:1905665

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MS4A1 hsa:931 path:hsa04640 Hematopoietic cell lineage - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MS4A1 IRF4 12676954 23180781 physical association anti tag coimmunoprecipitation InnateDB
MS4A1 USF1 23180781 9354667 physical association electrophoretic mobility supershift assay InnateDB
SPI1 MS4A1 23180781 9354667 physical association electrophoretic mobility supershift assay InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 MS4A1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
IRF4 MS4A1 19769942 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MS4A1 11226004 15892171 19769942 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001B968D MS4A1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C MS4A1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 MS4A1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 MS4A1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MS4A1 CD40 25361965 interaction type N/A PTMCode2
CD40 MS4A1 25361965 interaction type N/A PTMCode2
VIM MS4A1 25361965 interaction type N/A PTMCode2
MS4A1 VIM 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LMNA MS4A1 25348397 N/A physical interaction ComPPI
KASH5 MS4A1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 MS4A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LYN MS4A1 14525934 25348397 7545683 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK MS4A1 14525934 25348397 7545683 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FMNL1 MS4A1 25348397 N/A physical interaction ComPPI
HLA-DRB3 MS4A1 25348397 N/A physical interaction ComPPI
CSNK2A1 MS4A1 14525934 25348397 7678037 N/A experimental interaction detection,in vitro ComPPI,HPRD
CSNK2A2 MS4A1 14525934 25348397 7678037 N/A experimental interaction detection,in vitro ComPPI,HPRD
MDM2 MS4A1 25348397 N/A physical interaction ComPPI
CREB3 MS4A1 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FYN MS4A1 14525934 25348397 7545683 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MS4A1 CD40 14525934 25348397 27898060 9933087 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
MS4A1 HLA-DRA 20458337 22167754 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MS4A1 HLA-DRB1 25348397 N/A physical interaction ComPPI
MS4A1 HLA-DRB4 25348397 N/A physical interaction ComPPI
MS4A1 HLA-DRB5 25348397 N/A physical interaction ComPPI
MS4A1 PRDM1 25348397 N/A physical interaction ComPPI
MS4A1 IGHD 24234451 24963139 25348397 physical association proximity ligation assay ComPPI,IntAct
MS4A1 IGHM 24234451 24963139 25348397 physical association proximity ligation assay ComPPI,IntAct
MS4A1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 CREB3L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 CLEC14A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 GORAB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 IL7R 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 MMD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 RNF19B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 TSPO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 TMPPE 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 FAM209A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 LEUTX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDK7 MS4A1 27898060 7678037 N/A N/A OmniPath

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