GENE:MYLIP
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | MYLIP |
FullNmae | myosin regulatory light chain interacting protein |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:21155 |
EnsembleID | ENSG00000007944 |
Uniprot | Q8WY64 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
MYLIP | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
MYLIP | GO:0004842,GO:0004842,GO:0005515,GO:0005829,GO:0005856,GO:0005886,GO:0006511,GO:0007399,GO:0008092,GO:0010977,GO:0010989,GO:0016567,GO:0016567,GO:0031648,GO:0032803,GO:0042632,GO:0045732,GO:0046872,GO:0061630 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
MYLIP | hsa:29116 | path:hsa04979 | Cholesterol metabolism - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ESR1 | MYLIP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
ETS1 | MYLIP | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA1 | MYLIP | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | MYLIP | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA3 | MYLIP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXA1 | MYLIP | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | MYLIP | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | MYLIP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
PRDM14 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000039E1E1 | MYLIP | 17575136 \N | rna interference,inhibition | experimental interaction detection,western blot,miRNA interference luciferase reporter assay | miRSponge |
URS00002B3783 | MYLIP | 17575136 \N | rna interference,inhibition | experimental interaction detection,western blot,miRNA interference luciferase reporter assay | miRSponge |
URS00002B3783 | MYLIP | 17575136 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay | TarBase |
URS000039E1E1 | MYLIP | 17575136 20371350 21572407 23313552 23446348 23592263 23807165 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay | TarBase |
URS0000007FBA | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00000DDD35 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
URS000021D7C8 | MYLIP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000031B6ED | MYLIP | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003E2232 | MYLIP | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000250A40 | MYLIP | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C85B2 | MYLIP | 20371350 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002FC5B0 | MYLIP | 20371350 21572407 22473208 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000B989F | MYLIP | 20371350 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001A7F58 | MYLIP | 20371350 21572407 22473208 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000013ABA3 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00002E1509 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00004F859B | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000006F90B | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00001EB9FC | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000170CF4 | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000153377 | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000018E72A | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000045E0EC | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003FA24D | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000AD002 | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000045B99E | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00006DE17B | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000AD02D | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004C5774 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000260A3A | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000184017 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003A5E54 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000008A99 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000285DCB | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EFEC1 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002B0B46 | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000308E4D | MYLIP | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000010BD8D | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00001FA076 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000C36BD | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000025EABA | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000042E1F | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00002075FA | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000600E6 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS0000298BA3 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00001CC4BD | MYLIP | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004AE8D3 | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003CCBB9 | MYLIP | 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000034979B | MYLIP | 21572407 23313552 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000002569A | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003AAF6D | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000039A052 | MYLIP | 20371350 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075994C | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001DE669 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000005CF5F | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002152A8 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000065D58 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000012930C | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000277201 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000013E79D | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002A71AD | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000031602A | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000251D0B | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001C11BC | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002C0FCB | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000315338 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000027080C | MYLIP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000610EFA | MYLIP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003003B4 | MYLIP | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
GMCL1 | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
EXOSC5 | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
ARID5A | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
UBE2D1 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
RASSF5 | MYLIP | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
CRK | MYLIP | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
INO80B | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
DDIT4L | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
UBE2D4 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
UBE2D2 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
UBE2N | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
LDLR | MYLIP | 21685362 21734303 22109552 25348397 26666640 27898060 | N/A | physical interaction | ComPPI,OmniPath |
VLDLR | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
LRP8 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
CTR9 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
SDCBP | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
UBA6 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
ZBTB16 | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYCBP2 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
UBE2D3 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
SRPK2 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
KDM1A | MYLIP | 23455924 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
TSC22D4 | MYLIP | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
ZBTB18 | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
LNX2 | MYLIP | 21516116 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
MYLIP | MYL12B | 10593918 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
MYLIP | CNPY2 | 12826659 14525934 24234451 25348397 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
MYLIP | MTAP | 12826659 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
MYLIP | MIPOL1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
MYLIP | DAPP1 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,validated two hybrid | ComPPI,IntAct |
MYLIP | USP2 | 25348397 | N/A | physical interaction | ComPPI |
MYLIP | WDFY1 | 25348397 | N/A | physical interaction | ComPPI |
MYLIP | PAF1 | 25348397 | N/A | physical interaction | ComPPI |
MYLIP | PAX9 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | ZNF417 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | SCNM1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | KANK4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | FAM217B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | NHLRC4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | ZBTB42 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | ZNF438 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | EFHC2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MYLIP | MYLIP | 12826659 24234451 | physical association | pull down | IntAct |