Gene Information gene info

GENE:MYLIP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYLIP
FullNmae myosin regulatory light chain interacting protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21155
EnsembleID ENSG00000007944
Uniprot Q8WY64

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYLIP ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYLIP GO:0004842,GO:0004842,GO:0005515,GO:0005829,GO:0005856,GO:0005886,GO:0006511,GO:0007399,GO:0008092,GO:0010977,GO:0010989,GO:0016567,GO:0016567,GO:0031648,GO:0032803,GO:0042632,GO:0045732,GO:0046872,GO:0061630

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYLIP hsa:29116 path:hsa04979 Cholesterol metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 MYLIP 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 MYLIP 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 MYLIP 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 MYLIP 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MYLIP 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 MYLIP 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 MYLIP 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MYLIP 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MYLIP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MYLIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000039E1E1 MYLIP 17575136 \N rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS00002B3783 MYLIP 17575136 \N rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS00002B3783 MYLIP 17575136 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay TarBase
URS000039E1E1 MYLIP 17575136 20371350 21572407 23313552 23446348 23592263 23807165 24398324 25416803 26701625 27292025 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay TarBase
URS0000007FBA MYLIP 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000021D7C8 MYLIP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000031B6ED MYLIP 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E2232 MYLIP 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 MYLIP 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 MYLIP 20371350 21572407 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 MYLIP 20371350 21572407 22473208 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F MYLIP 20371350 21572407 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 MYLIP 20371350 21572407 22473208 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002E1509 MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F859B MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000006F90B MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001EB9FC MYLIP 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 MYLIP 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 MYLIP 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000018E72A MYLIP 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000045E0EC MYLIP 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D MYLIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 MYLIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E MYLIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B MYLIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D MYLIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004C5774 MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000260A3A MYLIP 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0B46 MYLIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D MYLIP 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001FA076 MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000C36BD MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000025EABA MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000042E1F MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002075FA MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000600E6 MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000298BA3 MYLIP 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001CC4BD MYLIP 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 MYLIP 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 MYLIP 21572407 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000034979B MYLIP 21572407 23313552 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000002569A MYLIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AAF6D MYLIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 MYLIP 20371350 21572407 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 MYLIP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C MYLIP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA MYLIP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 MYLIP 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MYLIP MTAP 25361965 interaction type N/A PTMCode2
MTAP MYLIP 25361965 interaction type N/A PTMCode2
CNPY2 MYLIP 25361965 interaction type N/A PTMCode2
MYLIP CNPY2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GMCL1 MYLIP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOSC5 MYLIP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ARID5A MYLIP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D1 MYLIP 25348397 N/A physical interaction ComPPI
RASSF5 MYLIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRK MYLIP 25348397 N/A two hybrid,physical interaction ComPPI
INO80B MYLIP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDIT4L MYLIP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D4 MYLIP 25348397 N/A physical interaction ComPPI
UBE2D2 MYLIP 25348397 N/A physical interaction ComPPI
UBE2N MYLIP 25348397 N/A physical interaction ComPPI
LDLR MYLIP 21685362 21734303 22109552 25348397 26666640 27898060 N/A physical interaction ComPPI,OmniPath
VLDLR MYLIP 25348397 N/A physical interaction ComPPI
LRP8 MYLIP 25348397 N/A physical interaction ComPPI
CTR9 MYLIP 25348397 N/A physical interaction ComPPI
SDCBP MYLIP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBA6 MYLIP 25348397 N/A physical interaction ComPPI
ZBTB16 MYLIP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYCBP2 MYLIP 25348397 N/A physical interaction ComPPI
UBE2D3 MYLIP 25348397 N/A physical interaction ComPPI
SRPK2 MYLIP 25348397 N/A physical interaction ComPPI
KDM1A MYLIP 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TSC22D4 MYLIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZBTB18 MYLIP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LNX2 MYLIP 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MYLIP MYL12B 10593918 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
MYLIP CNPY2 12826659 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MYLIP MTAP 12826659 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
MYLIP MIPOL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MYLIP DAPP1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
MYLIP USP2 25348397 N/A physical interaction ComPPI
MYLIP WDFY1 25348397 N/A physical interaction ComPPI
MYLIP PAF1 25348397 N/A physical interaction ComPPI
MYLIP PAX9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP ZNF417 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP SCNM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP KANK4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP FAM217B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP NHLRC4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP ZBTB42 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP ZNF438 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP EFHC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYLIP MYLIP 12826659 24234451 physical association pull down IntAct

Visualization