GENE:MYLIP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MYLIP |
| FullNmae | myosin regulatory light chain interacting protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21155 |
| EnsembleID | ENSG00000007944 |
| Uniprot | Q8WY64 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MYLIP | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MYLIP | GO:0004842,GO:0004842,GO:0005515,GO:0005829,GO:0005856,GO:0005886,GO:0006511,GO:0007399,GO:0008092,GO:0010977,GO:0010989,GO:0016567,GO:0016567,GO:0031648,GO:0032803,GO:0042632,GO:0045732,GO:0046872,GO:0061630 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MYLIP | hsa:29116 | path:hsa04979 | Cholesterol metabolism - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | MYLIP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | MYLIP | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA1 | MYLIP | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | MYLIP | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | MYLIP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | MYLIP | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | MYLIP | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | MYLIP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | MYLIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000039E1E1 | MYLIP | 17575136 \N | rna interference,inhibition | experimental interaction detection,western blot,miRNA interference luciferase reporter assay | miRSponge |
| URS00002B3783 | MYLIP | 17575136 \N | rna interference,inhibition | experimental interaction detection,western blot,miRNA interference luciferase reporter assay | miRSponge |
| URS00002B3783 | MYLIP | 17575136 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay | TarBase |
| URS000039E1E1 | MYLIP | 17575136 20371350 21572407 23313552 23446348 23592263 23807165 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay | TarBase |
| URS0000007FBA | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00000DDD35 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS000021D7C8 | MYLIP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000031B6ED | MYLIP | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E2232 | MYLIP | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000250A40 | MYLIP | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | MYLIP | 20371350 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | MYLIP | 20371350 21572407 22473208 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | MYLIP | 20371350 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | MYLIP | 20371350 21572407 22473208 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000013ABA3 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E1509 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F859B | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000006F90B | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EB9FC | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170CF4 | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000153377 | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018E72A | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045E0EC | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FA24D | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045B99E | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006DE17B | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD02D | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004C5774 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000260A3A | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000184017 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000008A99 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000285DCB | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFEC1 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0B46 | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000308E4D | MYLIP | 20371350 21572407 23446348 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000010BD8D | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FA076 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C36BD | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000025EABA | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | MYLIP | 20371350 21572407 23313552 23446348 23592263 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC4BD | MYLIP | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AE8D3 | MYLIP | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CCBB9 | MYLIP | 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000034979B | MYLIP | 21572407 23313552 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000002569A | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AAF6D | MYLIP | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A052 | MYLIP | 20371350 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075994C | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DE669 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CF5F | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065D58 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000277201 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000013E79D | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A71AD | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | MYLIP | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | MYLIP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000610EFA | MYLIP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003003B4 | MYLIP | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GMCL1 | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| EXOSC5 | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ARID5A | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBE2D1 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| RASSF5 | MYLIP | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CRK | MYLIP | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| INO80B | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| DDIT4L | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBE2D4 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D2 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| UBE2N | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| LDLR | MYLIP | 21685362 21734303 22109552 25348397 26666640 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| VLDLR | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| LRP8 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| CTR9 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| SDCBP | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBA6 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| ZBTB16 | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYCBP2 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D3 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| SRPK2 | MYLIP | 25348397 | N/A | physical interaction | ComPPI |
| KDM1A | MYLIP | 23455924 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| TSC22D4 | MYLIP | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| ZBTB18 | MYLIP | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| LNX2 | MYLIP | 21516116 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| MYLIP | MYL12B | 10593918 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| MYLIP | CNPY2 | 12826659 14525934 24234451 25348397 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| MYLIP | MTAP | 12826659 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| MYLIP | MIPOL1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| MYLIP | DAPP1 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,validated two hybrid | ComPPI,IntAct |
| MYLIP | USP2 | 25348397 | N/A | physical interaction | ComPPI |
| MYLIP | WDFY1 | 25348397 | N/A | physical interaction | ComPPI |
| MYLIP | PAF1 | 25348397 | N/A | physical interaction | ComPPI |
| MYLIP | PAX9 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | ZNF417 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | SCNM1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | KANK4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | FAM217B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | NHLRC4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | ZBTB42 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | ZNF438 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | EFHC2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MYLIP | MYLIP | 12826659 24234451 | physical association | pull down | IntAct |
