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GENE：PTCRA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTCRA
FullNmae pre T cell antigen receptor alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21290
EnsembleID ENSG00000171611
Uniprot Q6ISU1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTCRA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTCRA ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTCRA GO:0005515,GO:0016020,GO:0070244

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTCRA hsa:171558 path:hsa04330 Notch signaling pathway - Homo sapiens (human)
PTCRA hsa:171558 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TCF4 PTCRA 18854153 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
PTCRA PTCRA 1717999 20626350 26467481 bind,up-regulates activity N/A Signor

Source Target Pmid Interactiontype Methods Database
GATA2 PTCRA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA PTCRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTCRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTCRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB PTCRA N/A trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PTCRA N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
VCP PTCRA 25348397 N/A physical interaction ComPPI
UBC PTCRA 25348397 N/A physical interaction ComPPI
FEN1 PTCRA 25348397 N/A physical interaction ComPPI
HDLBP PTCRA 25348397 N/A physical interaction ComPPI
TCEA1 PTCRA 25348397 N/A physical interaction ComPPI
NOTCH3 PTCRA 25348397 N/A physical interaction ComPPI
HDGFL2 PTCRA 25348397 N/A physical interaction ComPPI
USP19 PTCRA 19465887 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CTH PTCRA 25348397 N/A physical interaction ComPPI
PTCRA LCK 20626350 27898060 stimulant N/A OmniPath
PTCRA ZAP70 1717999 27898060 stimulant N/A OmniPath

Visualization










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